Version 2.21.4
Genome Detective Platform

NGS Details (ERR138007_norovirus_amplicon_example): Human immunodeficiency virus 1

Assembly

8870 (1 contig(s))
19.1
1490
3175.25 rpm (after QC)
0
de novo + reference guided assembly
Bcf Tools

Coverage Map

Variant Tables

Assignment

Human immunodeficiency virus 1 (Taxonomy ID: 11676)
86.8403
82.5363
9
10

Alignment

12819.0 (NT) + 22371.0 (AA) = 35190.0
80.125
Global, seeded, nucleotide + amino acids (AGA)

Alignment Detailed Statistics

BeginEndCoverageScoreConcordanceMatchesIdentitiesI/D/M/F*Stop Codons
NT41891096.6%1281973.4%8808 (99.1%)7668 (86.2%)22/62
Mutations:47A>G, 96C>T, 152C>A, 161A>G, 213G>T, 214delG, 224G>A, 227C>A, 228T>A, 258C>T, 261G>A, 278G>A, 280delG, 305_306delAT, 317G>A, 369G>A, 378C>G, 379G>C, 380A>T, 404A>G, 424A>G, 426T>C, 435A>C, 467C>T, 471G>C, 474A>G, 479T>A, 485G>T, 486T>C, 507A>C, 510C>A, 516C>A, 518G>A, 525C>T, 557A>G, 560T>C, 562G>A, 579G>A, 585A>G, 586C>T, 595G>A, 599G>A, 607G>A, 609A>G, 615A>G, 632A>G, 641C>G, 645A>C, 656G>A, 666A>G, 669A>C, 670A>G, 672A>C, 677A>G, 678G>A, 689A>G, 690G>A, 692A>T, 698C>A, 700C>A, 704A>G, 705_716delCACAGCAATCAG, 722C>T, 740G>A, 746C>T, 747A>C, 749C>T, 755G>A, 767T>C, 771G>T, 773C>T, 774A>T, 806A>G, 809A>G, 810G>A, 827C>T, 830C>T, 839G>A, 869A>G, 875C>T, 897C>T, 902C>T, 944G>C, 974T>C, 978G>T, 980G>A, 987G>A, 988T>C, 989G>A, 992T>G, 998G>A, 1001T>C, 1004T>C, 1005G>C, 1007A>C, 1013C>T, 1019G>A, 1022A>G, 1028A>T, 1040C>T, 1046A>T, 1077G>C, 1078G>A, 1089A>G, 1090A>G, 1091T>C, 1094T>C, 1101A>G, 1109A>G, 1118T>A, 1133A>C, 1139G>A, 1173A>G, 1174C>T, 1182C>T, 1199A>G, 1205G>A, 1230C>A, 1237A>T, 1244T>C, 1253C>T, 1263T>A, 1271G>A, 1277A>G, 1278A>G, 1279A>G, 1292A>C, 1331T>C, 1354C>G, 1394A>G, 1403C>T, 1404G>A, 1430A>G, 1444T>C, 1452T>A, 1458A>G, 1460C>A, 1474G>A, 1476G>A, 1478C>T, 1481T>C, 1486G>A, 1488A>G, 1489A>G, 1498A>G, 1499G>A, 1508G>A, 1511T>C, 1514C>T, 1532G>A, 1537C>T, 1543G>A, 1562G>A, 1588A>G, 1589G>A, 1610T>C, 1613T>C, 1619G>A, 1643G>A, 1646C>T, 1656T>A, 1664A>G, 1670A>C, 1673G>A, 1676T>C, 1679T>C, 1680C>A, 1682T>C, 1687G>A, 1691A>G, 1701A>T, 1709A>G, 1714A>C, 1720G>A, 1725A>G, 1729C>T, 1730T>C, 1731G>A, 1735T>A, 1736A>G, 1745A>C, 1746_1748delACT, 1751C>A, 1752C>G, 1756A>C, 1768C>A, 1771T>A, 1776A>G, 1780A>G, 1787T>C, 1790_1791insCCC, 1794A>G, 1804G>A, 1805G>A, 1828C>A, 1839A>G, 1840G>A, 1841A>G, 1849G>A, 1852A>G, 1903A>C, 1906G>A, 1908G>A, 1920G>A, 1968G>A, 1979C>A, 1980A>G, 1981G>C, 1996C>T, 2005T>C, 2007A>G, 2008A>G, 2023A>G, 2038A>G, 2063C>A, 2071T>C, 2083C>T, 2098C>A, 2104C>T, 2131A>G, 2155A>G, 2194A>T, 2198G>A, 2199T>C, 2206T>A, 2211C>T, 2212A>G, 2215G>A, 2224G>A, 2230G>A, 2311A>G, 2341G>A, 2353C>T, 2356C>T, 2362A>G, 2380A>G, 2386C>A, 2407A>G, 2431T>G, 2452C>T, 2459G>A, 2461A>G, 2464C>T, 2476T>C, 2485T>C, 2499T>C, 2500A>C, 2518G>A, 2519A>G, 2524A>G, 2527T>C, 2548G>A, 2579A>T, 2580G>A, 2602G>T, 2605T>C, 2612A>G, 2613A>C, 2615C>A, 2638T>C, 2665A>G, 2683G>A, 2704G>A, 2708C>T, 2710G>A, 2714C>G, 2722G>A, 2723T>C, 2727G>A, 2728G>A, 2735C>T, 2737T>A, 2740C>T, 2761G>A, 2770T>C, 2788T>G, 2818A>G, 2828G>C, 2829T>A, 2830G>A, 2831C>T, 2839A>C, 2842A>G, 2863C>T, 2878G>A, 2881G>A, 2885T>C, 2887G>A, 2908C>T, 2925G>A, 2926G>A, 2947A>G, 2951A>G, 2956A>G, 2968A>C, 2969G>A, 2972A>G, 2974A>G, 2980A>G, 2983A>T, 2984G>A, 2985A>C, 2996C>T, 3002C>T, 3010A>G, 3013C>T, 3016A>G, 3043A>G, 3045T>C, 3046G>A, 3058A>G, 3088G>A, 3091G>A, 3100C>G, 3142G>A, 3154A>G, 3162G>A, 3170G>T, 3171G>C, 3196A>G, 3205G>A, 3217A>G, 3221A>T, 3223C>T, 3224A>C, 3225C>T, 3247A>C, 3259A>G, 3264A>G, 3268G>A, 3275C>T, 3276A>T, 3280G>A, 3283A>G, 3292A>T, 3310T>C, 3346T>C, 3355T>C, 3358C>T, 3359T>C, 3364G>A, 3368T>C, 3376C>T, 3385G>A, 3387A>C, 3391A>G, 3431G>T, 3436C>T, 3439G>A, 3445T>C, 3449T>A, 3450T>A, 3473A>G, 3475T>C, 3492T>C, 3493T>G, 3497A>T, 3508C>G, 3511A>T, 3524A>G, 3542T>C, 3544T>G, 3545C>T, 3553G>A, 3562G>A, 3567T>C, 3595A>G, 3629C>A, 3631A>G, 3667G>A, 3691T>C, 3695G>T, 3718A>G, 3775A>G, 3787A>G, 3799C>A, 3802A>G, 3805T>G, 3814G>A, 3825G>A, 3826T>C, 3856C>T, 3857C>A, 3859G>A, 3863C>G, 3889C>T, 3916A>G, 3940C>T, 3946T>C, 3952A>G, 3962C>T, 3989G>A, 4006T>C, 4015C>T, 4021A>G, 4024T>C, 4025A>C, 4042T>C, 4057G>A, 4060G>A, 4063A>G, 4069A>C, 4072T>C, 4075T>C, 4078T>A, 4079T>C, 4084A>G, 4120T>A, 4131G>C, 4142G>A, 4147T>C, 4155G>A, 4159C>A, 4162C>T, 4174G>A, 4177A>T, 4181A>C, 4201C>T, 4207T>C, 4258T>C, 4268G>A, 4276T>C, 4279G>A, 4303A>C, 4321C>T, 4354G>A, 4376G>A, 4407A>G, 4428C>T, 4444T>C, 4469A>G, 4471T>C, 4475C>G, 4498C>A, 4525A>C, 4534T>C, 4543C>A, 4549A>G, 4555G>T, 4622A>G, 4642G>A, 4643A>C, 4665C>T, 4674T>C, 4677G>A, 4683G>A, 4684G>A, 4691T>C, 4693G>A, 4694G>A, 4717A>T, 4725C>A, 4726C>G, 4727T>G, 4735G>A, 4765G>A, 4767G>A, 4768A>C, 4769T>A, 4773A>G, 4774G>A, 4778G>A, 4793T>C, 4799T>G, 4804A>T, 4806A>C, 4827T>C, 4857A>C, 4859A>G, 4860A>G, 4861A>G, 4865A>G, 4871C>A, 4878G>A, 4888A>G, 4889A>C, 4892A>G, 4904A>G, 4907T>C, 4911C>A, 4913G>A, 4919C>T, 4925C>T, 4937C>A, 4943T>C, 4949A>G, 4952G>A, 4956T>A, 4967C>T, 4969T>A, 4971G>A, 4986G>A, 4988A>C, 5012A>G, 5027C>T, 5037G>A, 5049A>G, 5051A>T, 5062T>C, 5069A>G, 5084T>C, 5085A>C, 5086C>A, 5093G>A, 5094A>G, 5095C>T, 5099G>A, 5102T>C, 5128A>G, 5147C>T, 5167G>T, 5213A>C, 5214T>C, 5215T>G, 5225G>A, 5233G>A, 5246G>A, 5248A>C, 5251T>C, 5268C>A, 5275G>T, 5278A>G, 5281C>A, 5290A>G, 5293T>A, 5294C>T, 5305G>A, 5320delT, 5333T>C, 5336A>T, 5352G>A, 5366G>A, 5371C>T, 5372A>G, 5384C>T, 5396G>A, 5397A>T, 5398C>T, 5403G>T, 5412G>C, 5424T>C, 5432A>C, 5437G>C, 5447A>G, 5448T>A, 5451C>T, 5461A>C, 5478C>T, 5479C>T, 5481A>C, 5482G>T, 5483T>G, 5484T>G, 5487T>C, 5490C>T, 5492T>C, 5496A>G, 5499A>G, 5501C>G, 5543G>C, 5548G>A, 5552A>C, 5556G>A, 5558A>G, 5567C>T, 5568T>A, 5576C>A, 5579C>T, 5581C>G, 5584T>C, 5599G>T, 5600_5601insGTTAAGC, 5602C>T, 5611C>T, 5612A>C, 5614C>A, 5615C>A, 5617A>T, 5619A>G, 5620C>T, 5621C>T, 5623A>G, 5624T>C, 5626G>A, 5630C>G, 5631A>C, 5636T>C, 5644G>A, 5653A>C, 5662G>A, 5677T>A, 5679C>T, 5684T>C, 5686A>T, 5687T>A, 5688C>T, 5704A>C, 5706A>G, 5707T>G, 5712A>G, 5725G>A, 5727C>T, 5734A>T, 5735T>A, 5737G>A, 5739T>A, 5743C>A, 5747T>G, 5748A>C, 5781A>G, 5784A>G, 5787A>T, 5788A>G, 5789T>C, 5791T>G, 5792C>A, 5793A>G, 5795C>A, 5797C>T, 5799T>G, 5801T>C, 5802G>A, 5804A>C, 5805G>A, 5806A>C, 5808G>T, 5813_5815delTGG, 5817G>A, 5818A>G, 5825A>C, 5826C>T, 5827C>T, 5828A>T, 5830G>A, 5831C>T, 5836T>G, 5841T>C, 5842G>A, 5845G>A, 5848G>A, 5856G>A, 5861A>G, 5869A>C, 5872G>A, 5878C>T, 5908G>A, 5920C>T, 5929T>C, 5948G>T, 5956T>A, 5958C>A, 5964T>C, 5974T>C, 5980C>T, 5989C>T, 6004C>T, 6010C>T, 6025A>T, 6026T>C, 6030T>A, 6037G>A, 6045A>G, 6046T>G, 6052C>T, 6059A>G, 6065G>A, 6079G>A, 6086G>A, 6087A>C, 6088G>A, 6130A>G, 6133A>G, 6153G>C, 6158A>G, 6160G>T, 6163C>T, 6165C>G, 6167G>A, 6169T>C, 6170T>A, 6172G>T, 6172_6173insGCC, 6174A>T, 6175G>C, 6180A>G, 6181T>C, 6184T>C, 6188A>G, 6189C>A, 6192A>C, 6195G>T, 6197A>G, 6198G>C, 6199T>C, 6201G>T, 6203G>A, 6204G>A, 6205G>T, 6206A>G, 6207G>A, 6208A>C, 6210T>C, 6211G>T, 6212A>C, 6214A>G, 6216T>A, 6220G>A, 6221A>G, 6223A>T, 6224G>C, 6225G>C, 6229_6230insGCA, 6233A>C, 6241C>T, 6252T>C, 6253C>A, 6255G>C, 6257A>G, 6260A>G, 6261G>A, 6262C>A, 6270G>A, 6275G>C, 6276T>A, 6279A>T, 6285A>T, 6287T>C, 6289T>G, 6293T>C, 6314A>G, 6318C>A, 6322A>C, 6323G>A, 6325T>C, 6328T>G, 6331_6332insGAC, 6333C>A, 6336C>G, 6337C>A, 6339G>C, 6340C>A, 6343T>C, 6345A>G, 6346G>A, 6347T>C, 6349G>A, 6351C>T, 6354G>A, 6359A>G, 6361C>T, 6368G>A, 6369T>C, 6382C>T, 6397C>T, 6399T>G, 6400T>G, 6403G>T, 6427C>T, 6430G>A, 6438T>A, 6451A>G, 6458A>G, 6460T>G, 6463G>A, 6465C>A, 6466G>T, 6471A>C, 6472T>A, 6475A>G, 6481A>G, 6482C>T, 6487T>C, 6489C>A, 6490A>G, 6499C>T, 6525G>A, 6526G>A, 6532A>G, 6538A>C, 6545C>T, 6548C>T, 6562T>C, 6573A>G, 6578G>A, 6586T>C, 6593G>C, 6594T>A, 6595C>A, 6599T>A, 6602A>T, 6604G>A, 6607C>T, 6613T>A, 6628A>G, 6631G>C, 6634G>T, 6637C>T, 6638A>G, 6639C>A, 6647G>C, 6649A>G, 6691C>A, 6692C>T, 6693G>C, 6695A>T, 6697C>A, 6698_6703delCAGAGA, 6712G>A, 6713A>C, 6717C>T, 6722G>T, 6723T>A, 6729T>C, 6734A>G, 6739_6740insATA, 6743A>G, 6745T>C, 6748G>C, 6752C>A, 6754A>G, 6767A>G, 6773A>G, 6776G>A, 6779A>C, 6786A>G, 6787T>G, 6793T>G, 6797A>G, 6798A>C, 6800C>A, 6803A>G, 6806G>A, 6807C>A, 6808T>G, 6809A>G, 6810G>C, 6811C>A, 6814A>G, 6818A>G, 6820A>G, 6821G>T, 6822A>C, 6823A>T, 6824C>T, 6826A>T, 6829T>C, 6830_6832delGGA, 6833A>C, 6834A>C, 6839A>G, 6840A>C, 6849T>A, 6850C>A, 6856G>C, 6857C>T, 6858A>C, 6876C>T, 6884G>A, 6885T>C, 6888C>G, 6892C>T, 6894G>A, 6905G>A, 6906G>T, 6907A>G, 6910G>A, 6929T>A, 6932A>G, 6933C>A, 6934A>T, 6935C>G, 6947A>G, 6948G>A, 6949T>C, 6952T>A, 6953T>A, 6954G>A, 6955G>A, 6958T>C, 6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT, 6989A>G, 6994T>A, 6996A>G, 6998G>T, 6999G>T, 7000A>C, 7002G>A, 7005A>G, 7009A>T, 7015C>T, 7024C>T, 7025A>C, 7040A>G, 7042A>G, 7055A>G, 7060A>G, 7064A>C, 7065A>G, 7079C>A, 7080C>A, 7087C>T, 7088A>G, 7089G>C, 7090T>A, 7094C>A, 7095A>C, 7099T>C, 7101G>C, 7102A>C, 7106T>A, 7107C>A, 7108A>C, 7123G>T, 7132A>G, 7148A>C, 7149A>T, 7150T>G, 7152G>A, 7153C>T, 7156C>T, 7158A>C, 7160G>A, 7162_7164delGTC, 7165C>T, 7183A>G, 7190G>A, 7197G>A, 7198G>A, 7238A>G, 7250T>C, 7276G>A, 7280A>C, 7281G>A, 7289C>A, 7299A>G, 7313A>C, 7322T>C, 7348A>T, 7366A>G, 7369C>G, 7375G>A, 7411T>A, 7420G>A, 7428A>G, 7433T>C, 7450G>A, 7471A>G, 7489C>T, 7492G>A, 7508A>G, 7549G>A, 7553A>C, 7561T>C, 7579T>C, 7589G>A, 7590C>A, 7597T>C, 7603T>C, 7604G>T, 7627G>T, 7630A>G, 7631C>G, 7640A>G, 7641A>G, 7642T>G, 7643C>A, 7647C>T, 7666C>A, 7668G>A, 7672A>G, 7673A>G, 7677A>G, 7685A>T, 7689G>A, 7690C>A, 7691T>G, 7692T>A, 7697C>T, 7700T>A, 7701C>G, 7702C>G, 7714A>C, 7720A>G, 7729A>G, 7753G>A, 7755A>C, 7759A>G, 7762T>C, 7775T>C, 7790A>G, 7796A>T, 7799A>C, 7801T>A, 7820T>A, 7847G>A, 7852T>C, 7868G>A, 7873A>G, 7885G>A, 7898C>A, 7906T>C, 7912A>T, 7915A>G, 7918G>A, 7930C>T, 7931C>A, 7938C>G, 7947G>A, 7969A>C, 7977A>G, 7988A>C, 7989G>A, 7992A>G, 7995G>A, 8006A>G, 8008T>G, 8009C>A, 8016T>C, 8023A>T, 8025C>T, 8029G>A, 8032A>T, 8036A>G, 8037T>C, 8047T>C, 8055G>A, 8076A>G, 8079G>A, 8092A>C, 8093C>A, 8095C>A, 8098G>A, 8103T>C, 8105A>G, 8119A>C, 8120C>A, 8121T>G, 8122T>G, 8123C>G, 8124T>G, 8126G>C, 8127G>T, 8128A>G, 8129C>A, 8131C>G, 8146C>T, 8156T>C, 8157G>T, 8159T>G, 8168C>A, 8169T>C, 8180A>G, 8200T>C, 8204G>A, 8215C>T, 8227C>A, 8243G>T, 8254G>A, 8265T>C, 8266A>T, 8267G>T, 8269A>G, 8273G>A, 8279T>G, 8292G>T, 8294C>A, 8330A>G, 8331T>C, 8336C>T, 8342G>A, 8370G>A, 8372G>A, 8373A>G, 8385A>G, 8388G>A, 8400A>C, 8409G>A, 8411T>C, 8412G>C, 8413A>C, 8414G>T, 8426T>G, 8427A>G, 8440C>T, 8441A>G, 8446G>A, 8451C>T, 8453G>A, 8458A>G, 8461A>G, 8462T>G, 8465A>G, 8471C>T, 8477T>C, 8486A>T, 8487G>A, 8488C>G, 8494C>A, 8495C>T, 8499G>C, 8503C>A, 8504T>C, 8506G>T, 8507T>G, 8516A>G, 8531G>A, 8534G>C, 8537G>A, 8540G>A, 8543T>C, 8554C>G, 8582T>C, 8585C>T, 8590C>G, 8603T>C, 8606C>T, 8640C>T, 8646C>T, 8652C>A, 8654A>G, 8656G>A, 8666T>G, 8682A>G, 8713A>G, 8739G>A, 8757T>A, 8759T>G, 8762A>G, 8770A>T, 8789G>C, 8795T>G, 8796A>G, 8799A>G, 8805G>A, 8814A>G, 8827C>A, 8829A>T, 8835T>C, 8844G>A, 8851T>A, 8852G>A, 8858G>A, 8864T>G, 8867C>T, 8868C>G, 8869C>A, 8870G>A, 8873G>C, 8875G>A, 8883T>C, 8885A>G, 8886G>A, 8892A>G, 8893G>A, 8901A>G, 8907C>T, 8909A>G
CDS
11436100%924792.1%1431 (99.6%)1287 (89.6%)1/5/0/01
Protein mutations:E12K (369G>A), R15A (378C>G 379G>C 380A>T), K30R (424A>G), I34L (435A>C), V46L (471G>C), N47D (474A>G), Q59K (510C>A), L61I (516C>A 518G>A), R76K (562G>A), V82I (579G>A), T84V (585A>G 586C>T), C87Y (595G>A), R91K (607G>A), I92V (609A>G), I94V (615A>G), D102E (641C>G), I104L (645A>C), S111G (666A>G), K112R (669A>C 670A>G), K113Q (672A>C), A115T (678G>A), A119T (690G>A 692A>T), D121E (698C>A), T122K (700C>A), H124_Q127del (705_716delCACAGCAATCAG), I138L (747A>C 749C>T), A146S (771G>T 773C>T), I147L (774A>T), V159I (810G>A), E203D (944G>C), V215L (978G>T 980G>A), V218T (987G>A 988T>C 989G>A), H219Q (992T>G), A224P (1005G>C 1007A>C), M228I (1019G>A), G248Q (1077G>C 1078G>A), N252G (1089A>G 1090A>G 1091T>C), I256V (1101A>G), T280V (1173A>G 1174C>T), Y301F (1237A>T), S310T (1263T>A), N315G (1278A>G 1279A>G), E319D (1292A>C), A340G (1354C>G), G357S (1404G>A), V370A (1444T>C), S373T (1452T>A), T375A (1458A>G 1460C>A), R380K (1474G>A), G381S (1476G>A 1478C>T), R384K (1486G>A), N385G (1488A>G 1489A>G), K388R (1498A>G 1499G>A), T401I (1537C>T), R403K (1543G>A), K418R (1588A>G 1589G>A), D437N (1643G>A), L441Q (1656T>A), K444E (1664A>G), E447K (1673G>A), F448L (1676T>C), S449H (1679T>C 1680C>A), S450P (1682T>C), T453A (1691A>G), N456I (1701A>T), T459A (1709A>G), R460S (1714A>C), Q464R (1725A>G), W466Q (1730T>C 1731G>A), R468G (1736A>G), N471del (1745A>C 1746_1748delACT), S472P (1746_1748delACT), P473S (1751C>A 1752C>G), D479E (1771T>A), Q481R (1776A>G), S485P (1787T>C), S485_F486insS (1790_1791insCCC), F486L (1790_1791insCCC), N487S (1794A>G), V491I (1805G>A), K502R (1839A>G 1840G>A), I503V (1841A>G), E523D (1903A>C), M524I (1906G>A), S525N (1908G>A), R529K (1920G>A), R545K (1968G>A), Q549S (1979C>A 1980A>G 1981G>C), K558R (2007A>G 2008A>G), L577M (2063C>A), V622T (2198G>A 2199T>C), T626M (2211C>T 2212A>G), E709K (2459G>A 2461A>G), I722T (2499T>C 2500A>C), I729V (2519A>G), S749Y (2579A>T 2580G>A), E756D (2602G>T), K760A (2612A>G 2613A>C), Q761K (2615C>A), Q794E (2714C>G), R798K (2727G>A 2728G>A), V832Q (2828G>C 2829T>A 2830G>A), E835D (2839A>C), R864K (2925G>A 2926G>A), T873A (2951A>G), E878D (2968A>C), V879I (2969G>A), I880V (2972A>G 2974A>G), E884T (2984G>A 2985A>C), V904A (3045T>C 3046G>A), R943K (3162G>A), G946S (3170G>T 3171G>C), T963S (3221A>T 3223C>T), T964L (3224A>C 3225C>T), K977R (3264A>G), Q981L (3275C>T 3276A>T), E986D (3292A>T), K1018T (3387A>C), A1033S (3431G>T), L1039K (3449T>A 3450T>A), N1047D (3473A>G 3475T>C), V1053A (3492T>C 3493T>G), T1055S (3497A>T), D1058E (3508C>G), T1064A (3524A>G), Y1070Q (3542T>C 3544T>G), L1078S (3567T>C), Q1099K (3629C>A 3631A>G), A1121S (3695G>T), D1157E (3805T>G), S1164N (3825G>A 3826T>C), L1175I (3857C>A 3859G>A), P1177A (3863C>G), V1219I (3989G>A), I1231L (4025A>C), S1266T (4131G>C), G1270S (4142G>A), R1274K (4155G>A), K1283Q (4181A>C), V1312I (4268G>A), V1348I (4376G>A), K1358R (4407A>G), T1365I (4428C>T), N1379D (4469A>G 4471T>C), L1381V (4475C>G), D1403E (4543C>A), S1430G (4622A>G)
Codon mutations:GAA12AAA (369G>A), CGA15GCT (378C>G 379G>C 380A>T), CCA23CCG (404A>G), AAA30AGA (424A>G), TTA31CTA (426T>C), ATA34CTA (435A>C), TTC44TTT (467C>T), GTT46CTT (471G>C), AAT47GAT (474A>G), CCT48CCA (479T>A), CTG50CTT (485G>T), TTA51CTA (486T>C), AGA58CGA (507A>C), CAA59AAA (510C>A), CTG61ATA (516C>A 518G>A), CTA64TTA (525C>T), GAA74GAG (557A>G), CTT75CTC (560T>C), AGA76AAA (562G>A), GTA82ATA (579G>A), ACC84GTC (585A>G 586C>T), TGT87TAT (595G>A), GTG88GTA (599G>A), AGG91AAG (607G>A), ATA92GTA (609A>G), ATA94GTA (615A>G), GAA99GAG (632A>G), GAC102GAG (641C>G), ATA104CTA (645A>C), GAG107GAA (656G>A), AGT111GGT (666A>G), AAG112CGG (669A>C 670A>G), AAA113CAA (672A>C), AAA114AAG (677A>G), GCA115ACA (678G>A), GCA118GCG (689A>G), GCA119ACT (690G>A 692A>T), GAC121GAA (698C>A), ACA122AAA (700C>A), GGA123GGG (704A>G), CAC124_CAG127del (705_716delCACAGCAATCAG), AGC129AGT (722C>T), GTG135GTA (740G>A), AAC137AAT (746C>T), ATC138CTT (747A>C 749C>T), GGG140GGA (755G>A), CAT144CAC (767T>C), GCC146TCT (771G>T 773C>T), ATA147TTA (774A>T), AAA157AAG (806A>G), GTA158GTG (809A>G), GTA159ATA (810G>A), TTC164TTT (827C>T), AGC165AGT (830C>T), GTG168GTA (839G>A), GGA178GGG (869A>G), ACC180ACT (875C>T), CTA188TTA (897C>T), AAC189AAT (902C>T), GAG203GAC (944G>C), GAT213GAC (974T>C), GTG215TTA (978G>T 980G>A), GTG218ACA (987G>A 988T>C 989G>A), CAT219CAG (992T>G), GGG221GGA (998G>A), CCT222CCC (1001T>C), ATT223ATC (1004T>C), GCA224CCC (1005G>C 1007A>C), GGC226GGT (1013C>T), ATG228ATA (1019G>A), AGA229AGG (1022A>G), CCA231CCT (1028A>T), GAC235GAT (1040C>T), GCA237GCT (1046A>T), GGA248CAA (1077G>C 1078G>A), AAT252GGC (1089A>G 1090A>G 1091T>C), AAT253AAC (1094T>C), ATC256GTC (1101A>G), GTA258GTG (1109A>G), ATT261ATA (1118T>A), ATA266ATC (1133A>C), CTG268CTA (1139G>A), ACC280GTC (1173A>G 1174C>T), CTG283TTG (1182C>T), GGA288GGG (1199A>G), AAG290AAA (1205G>A), CGG299AGG (1230C>A), TAT301TTT (1237A>T), ACT303ACC (1244T>C), GCC306GCT (1253C>T), TCA310ACA (1263T>A), GAG312GAA (1271G>A), AAA314AAG (1277A>G), AAT315GGT (1278A>G 1279A>G), GAA319GAC (1292A>C), ACT332ACC (1331T>C), GCG340GGG (1354C>G), GTA353GTG (1394A>G), CCC356CCT (1403C>T), GGC357AGC (1404G>A), GAA365GAG (1430A>G), GTA370GCA (1444T>C), TCA373ACA (1452T>A), ACC375GCA (1458A>G 1460C>A), AGA380AAA (1474G>A), GGC381AGT (1476G>A 1478C>T), AAT382AAC (1481T>C), AGG384AAG (1486G>A), AAC385GGC (1488A>G 1489A>G), AAG388AGA (1498A>G 1499G>A), AAG391AAA (1508G>A), TGT392TGC (1511T>C), TTC393TTT (1514C>T), GGG399GGA (1532G>A), ACA401ATA (1537C>T), AGA403AAA (1543G>A), AGG409AGA (1562G>A), AAG418AGA (1588A>G 1589G>A), GAT425GAC (1610T>C), TGT426TGC (1613T>C), GAG428GAA (1619G>A), GAT437AAT (1643G>A), CTG438TTG (1646C>T), CTA441CAA (1656T>A), AAG444GAG (1664A>G), AGG446CGG (1670A>C), GAA447AAA (1673G>A), TTT448CTT (1676T>C), TCT449CAT (1679T>C 1680C>A), TCA450CCA (1682T>C), GAG451GAA (1687G>A), ACC453GCC (1691A>G), AAC456ATC (1701A>T), ACC459GCC (1709A>G), AGA460AGC (1714A>C), GAG462GAA (1720G>A), CAG464CGG (1725A>G), GTC465GTT (1729C>T), TGG466CAG (1730T>C 1731G>A), GGT467GGA (1735T>A), AGA468GGA (1736A>G), AAC471del (1745A>C 1746_1748delACT), TCC472CCC (1746_1748delACT), CCC473AGC (1751C>A 1752C>G), TCA474TCC (1756A>C), GCC478GCA (1768C>A), GAT479GAA (1771T>A), CAA481CGA (1776A>G), GGA482GGG (1780A>G), TCC485CCC (1787T>C), TCC485_TTT486insTCC (1790_1791insCCC), TTT486CTT (1790_1791insCCC), AAC487AGC (1794A>G), CAG490CAA (1804G>A), GTC491ATC (1805G>A), CTC498CTA (1828C>A), AAG502AGA (1839A>G 1840G>A), ATA503GTA (1841A>G), GGG505GGA (1849G>A), CAA506CAG (1852A>G), GAA523GAC (1903A>C), ATG524ATA (1906G>A), AGT525AAT (1908G>A), AGA529AAA (1920G>A), AGA545AAA (1968G>A), CAG549AGC (1979C>A 1980A>G 1981G>C), ATC554ATT (1996C>T), CAT557CAC (2005T>C), AAA558AGG (2007A>G 2008A>G), GTA563GTG (2023A>G), ACA568ACG (2038A>G), CTG577ATG (2063C>A), ACT579ACC (2071T>C), TGC583TGT (2083C>T), CCC588CCA (2098C>A), AGC590AGT (2104C>T), TTA599TTG (2131A>G), AAA607AAG (2155A>G), GCA620GCT (2194A>T), GTA622ACA (2198G>A 2199T>C), ATT624ATA (2206T>A), ACA626ATG (2211C>T 2212A>G), GAG627GAA (2215G>A), AAG630AAA (2224G>A), GGG632GGA (2230G>A), AGA659AGG (2311A>G), AAG669AAA (2341G>A), GAC673GAT (2353C>T), TTC674TTT (2356C>T), GAA676GAG (2362A>G), CCA682CCG (2380A>G), CCC684CCA (2386C>A), AAA691AAG (2407A>G), GGT699GGG (2431T>G), CCC706CCT (2452C>T), GAA709AAG (2459G>A 2461A>G), GAC710GAT (2464C>T), TAT714TAC (2476T>C), TTT717TTC (2485T>C), ATA722ACC (2499T>C 2500A>C), GGG728GGA (2518G>A), ATT729GTT (2519A>G), AGA730AGG (2524A>G), TAT731TAC (2527T>C), CAG738CAA (2548G>A), AGT749TAT (2579A>T 2580G>A), GAG756GAT (2602G>T), CCT757CCC (2605T>C), AAA760GCA (2612A>G 2613A>C), CAA761AAA (2615C>A), TAT768TAC (2638T>C), GGA777GGG (2665A>G), GGG783GGA (2683G>A), GAG790GAA (2704G>A), CTG792TTA (2708C>T 2710G>A), CAA794GAA (2714C>G), CTG796CTA (2722G>A), TTG797CTG (2723T>C), AGG798AAA (2727G>A 2728G>A), CTT801TTA (2735C>T 2737T>A), ACC802ACT (2740C>T), CAG809CAA (2761G>A), CCT812CCC (2770T>C), GGT818GGG (2788T>G), GTA828GTG (2818A>G), GTG832CAA (2828G>C 2829T>A 2830G>A), CTG833TTG (2831C>T), GAA835GAC (2839A>C), AAA836AAG (2842A>G), GAC843GAT (2863C>T), GTG848GTA (2878G>A), GGG849GGA (2881G>A), TTG851CTA (2885T>C 2887G>A), TAC858TAT (2908C>T), AGG864AAA (2925G>A 2926G>A), AGA871AGG (2947A>G), ACC873GCC (2951A>G), AAA874AAG (2956A>G), GAA878GAC (2968A>C), GTA879ATA (2969G>A), ATA880GTG (2972A>G 2974A>G), CTA882CTG (2980A>G), ACA883ACT (2983A>T), GAA884ACA (2984G>A 2985A>C), CTA888TTA (2996C>T), CTG890TTG (3002C>T), GAA892GAG (3010A>G), AAC893AAT (3013C>T), AGA894AGG (3016A>G), GGA903GGG (3043A>G), GTG904GCA (3045T>C 3046G>A), CCA908CCG (3058A>G), AAG918AAA (3088G>A), CAG919CAA (3091G>A), GGC922GGG (3100C>G), CTG936CTA (3142G>A), AAA940AAG (3154A>G), AGA943AAA (3162G>A), GGT946TCT (3170G>T 3171G>C), CAA954CAG (3196A>G), GAG957GAA (3205G>A), AAA961AAG (3217A>G), ACC963TCT (3221A>T 3223C>T), ACA964CTA (3224A>C 3225C>T), GGA971GGC (3247A>C), AAA975AAG (3259A>G), AAA977AGA (3264A>G), CTG978CTA (3268G>A), CAA981TTA (3275C>T 3276A>T), AAG982AAA (3280G>A), GAA983GAG (3283A>G), GAA986GAT (3292A>T), TAT992TAC (3310T>C), GTT1004GTC (3346T>C), CCT1007CCC (3355T>C), CCC1008CCT (3358C>T), TTA1009CTA (3359T>C), GTG1010GTA (3364G>A), TTA1012CTA (3368T>C), TAC1014TAT (3376C>T), GAG1017GAA (3385G>A), AAA1018ACA (3387A>C), GAA1019GAG (3391A>G), GCT1033TCT (3431G>T), AAC1034AAT (3436C>T), AGG1035AGA (3439G>A), ACT1037ACC (3445T>C), TTA1039AAA (3449T>A 3450T>A), AAT1047GAC (3473A>G 3475T>C), GTT1053GCG (3492T>C 3493T>G), ACC1055TCC (3497A>T), GAC1058GAG (3508C>G), ACA1059ACT (3511A>T), ACT1064GCT (3524A>G), TAT1070CAG (3542T>C 3544T>G), CTA1071TTA (3545C>T), TTG1073TTA (3553G>A), TCG1076TCA (3562G>A), TTA1078TCA (3567T>C), CAA1087CAG (3595A>G), CAA1099AAG (3629C>A 3631A>G), CAG1111CAA (3667G>A), TAT1119TAC (3691T>C), GCA1121TCA (3695G>T), GGA1128GGG (3718A>G), CTA1147CTG (3775A>G), GGA1151GGG (3787A>G), GCC1155GCA (3799C>A), CAA1156CAG (3802A>G), GAT1157GAG (3805T>G), GAG1160GAA (3814G>A), AGT1164AAC (3825G>A 3826T>C), AAC1174AAT (3856C>T), CTG1175ATA (3857C>A 3859G>A), CCT1177GCT (3863C>G), GCC1185GCT (3889C>T), GGA1194GGG (3916A>G), GAC1202GAT (3940C>T), AGT1204AGC (3946T>C), GGA1206GGG (3952A>G), CTA1210TTA (3962C>T), GTT1219ATT (3989G>A), GTT1224GTC (4006T>C), GCC1227GCT (4015C>T), GGA1229GGG (4021A>G), TAT1230TAC (4024T>C), ATA1231CTA (4025A>C), ATT1236ATC (4042T>C), GGG1241GGA (4057G>A), CAG1242CAA (4060G>A), GAA1243GAG (4063A>G), GCA1245GCC (4069A>C), TAT1246TAC (4072T>C), TTT1247TTC (4075T>C), CTT1248CTA (4078T>A), TTA1249CTA (4079T>C), AAA1250AAG (4084A>G), ACT1262ACA (4120T>A), AGC1266ACC (4131G>C), GGT1270AGT (4142G>A), GCT1271GCC (4147T>C), AGG1274AAG (4155G>A), GCC1275GCA (4159C>A), GCC1276GCT (4162C>T), GCG1280GCA (4174G>A), GGA1281GGT (4177A>T), AAG1283CAG (4181A>C), CCC1289CCT (4201C>T), AAT1291AAC (4207T>C), ATT1308ATC (4258T>C), GTA1312ATA (4268G>A), GAT1314GAC (4276T>C), CAG1315CAA (4279G>A), GTA1323GTC (4303A>C), ATC1329ATT (4321C>T), GGG1340GGA (4354G>A), GTA1348ATA (4376G>A), AAA1358AGA (4407A>G), ACA1365ATA (4428C>T), TTT1370TTC (4444T>C), AAT1379GAC (4469A>G 4471T>C), CTT1381GTT (4475C>G), CTC1388CTA (4498C>A), GTA1397GTC (4525A>C), GAT1400GAC (4534T>C), GAC1403GAA (4543C>A), AAA1405AAG (4549A>G), GTG1407GTT (4555G>T), AGT1430GGT (4622A>G), TAG1436TAA (4642G>A)
1501100%302787.4%496 (98.8%)422 (84.1%)1/5/0/02
Protein mutations:E12K (369G>A), R15A (378C>G 379G>C 380A>T), K30R (424A>G), I34L (435A>C), V46L (471G>C), N47D (474A>G), Q59K (510C>A), L61I (516C>A 518G>A), R76K (562G>A), V82I (579G>A), T84V (585A>G 586C>T), C87Y (595G>A), R91K (607G>A), I92V (609A>G), I94V (615A>G), D102E (641C>G), I104L (645A>C), S111G (666A>G), K112R (669A>C 670A>G), K113Q (672A>C), A115T (678G>A), A119T (690G>A 692A>T), D121E (698C>A), T122K (700C>A), H124_Q127del (705_716delCACAGCAATCAG), I138L (747A>C 749C>T), A146S (771G>T 773C>T), I147L (774A>T), V159I (810G>A), E203D (944G>C), V215L (978G>T 980G>A), V218T (987G>A 988T>C 989G>A), H219Q (992T>G), A224P (1005G>C 1007A>C), M228I (1019G>A), G248Q (1077G>C 1078G>A), N252G (1089A>G 1090A>G 1091T>C), I256V (1101A>G), T280V (1173A>G 1174C>T), Y301F (1237A>T), S310T (1263T>A), N315G (1278A>G 1279A>G), E319D (1292A>C), A340G (1354C>G), G357S (1404G>A), V370A (1444T>C), S373T (1452T>A), T375A (1458A>G 1460C>A), R380K (1474G>A), G381S (1476G>A 1478C>T), R384K (1486G>A), N385G (1488A>G 1489A>G), K388R (1498A>G 1499G>A), T401I (1537C>T), R403K (1543G>A), K418R (1588A>G 1589G>A), Y441N (1656T>A), L449I (1680C>A 1682T>C), S451N (1687G>A), T456S (1701A>T), E460A (1714A>C), S462N (1720G>A), R464G (1725A>G), S465F (1729C>T 1730T>C), G466R (1731G>A), V467E (1735T>A 1736A>G), T471del (1746_1748delACT), P473A (1752C>G), Q474P (1756A>C), P478Q (1768C>A), I479K (1771T>A), K481E (1776A>G), E482G (1780A>G), P485_L486insP (1790_1791insCCC), T487A (1794A>G), R490K (1804G>A 1805G>A), S498* (1828C>A)
Codon mutations:GAA12AAA (369G>A), CGA15GCT (378C>G 379G>C 380A>T), CCA23CCG (404A>G), AAA30AGA (424A>G), TTA31CTA (426T>C), ATA34CTA (435A>C), TTC44TTT (467C>T), GTT46CTT (471G>C), AAT47GAT (474A>G), CCT48CCA (479T>A), CTG50CTT (485G>T), TTA51CTA (486T>C), AGA58CGA (507A>C), CAA59AAA (510C>A), CTG61ATA (516C>A 518G>A), CTA64TTA (525C>T), GAA74GAG (557A>G), CTT75CTC (560T>C), AGA76AAA (562G>A), GTA82ATA (579G>A), ACC84GTC (585A>G 586C>T), TGT87TAT (595G>A), GTG88GTA (599G>A), AGG91AAG (607G>A), ATA92GTA (609A>G), ATA94GTA (615A>G), GAA99GAG (632A>G), GAC102GAG (641C>G), ATA104CTA (645A>C), GAG107GAA (656G>A), AGT111GGT (666A>G), AAG112CGG (669A>C 670A>G), AAA113CAA (672A>C), AAA114AAG (677A>G), GCA115ACA (678G>A), GCA118GCG (689A>G), GCA119ACT (690G>A 692A>T), GAC121GAA (698C>A), ACA122AAA (700C>A), GGA123GGG (704A>G), CAC124_CAG127del (705_716delCACAGCAATCAG), AGC129AGT (722C>T), GTG135GTA (740G>A), AAC137AAT (746C>T), ATC138CTT (747A>C 749C>T), GGG140GGA (755G>A), CAT144CAC (767T>C), GCC146TCT (771G>T 773C>T), ATA147TTA (774A>T), AAA157AAG (806A>G), GTA158GTG (809A>G), GTA159ATA (810G>A), TTC164TTT (827C>T), AGC165AGT (830C>T), GTG168GTA (839G>A), GGA178GGG (869A>G), ACC180ACT (875C>T), CTA188TTA (897C>T), AAC189AAT (902C>T), GAG203GAC (944G>C), GAT213GAC (974T>C), GTG215TTA (978G>T 980G>A), GTG218ACA (987G>A 988T>C 989G>A), CAT219CAG (992T>G), GGG221GGA (998G>A), CCT222CCC (1001T>C), ATT223ATC (1004T>C), GCA224CCC (1005G>C 1007A>C), GGC226GGT (1013C>T), ATG228ATA (1019G>A), AGA229AGG (1022A>G), CCA231CCT (1028A>T), GAC235GAT (1040C>T), GCA237GCT (1046A>T), GGA248CAA (1077G>C 1078G>A), AAT252GGC (1089A>G 1090A>G 1091T>C), AAT253AAC (1094T>C), ATC256GTC (1101A>G), GTA258GTG (1109A>G), ATT261ATA (1118T>A), ATA266ATC (1133A>C), CTG268CTA (1139G>A), ACC280GTC (1173A>G 1174C>T), CTG283TTG (1182C>T), GGA288GGG (1199A>G), AAG290AAA (1205G>A), CGG299AGG (1230C>A), TAT301TTT (1237A>T), ACT303ACC (1244T>C), GCC306GCT (1253C>T), TCA310ACA (1263T>A), GAG312GAA (1271G>A), AAA314AAG (1277A>G), AAT315GGT (1278A>G 1279A>G), GAA319GAC (1292A>C), ACT332ACC (1331T>C), GCG340GGG (1354C>G), GTA353GTG (1394A>G), CCC356CCT (1403C>T), GGC357AGC (1404G>A), GAA365GAG (1430A>G), GTA370GCA (1444T>C), TCA373ACA (1452T>A), ACC375GCA (1458A>G 1460C>A), AGA380AAA (1474G>A), GGC381AGT (1476G>A 1478C>T), AAT382AAC (1481T>C), AGG384AAG (1486G>A), AAC385GGC (1488A>G 1489A>G), AAG388AGA (1498A>G 1499G>A), AAG391AAA (1508G>A), TGT392TGC (1511T>C), TTC393TTT (1514C>T), GGG399GGA (1532G>A), ACA401ATA (1537C>T), AGA403AAA (1543G>A), AGG409AGA (1562G>A), AAG418AGA (1588A>G 1589G>A), GAT425GAC (1610T>C), TGT426TGC (1613T>C), GAG428GAA (1619G>A), AAG436AAA (1643G>A), ATC437ATT (1646C>T), TAC441AAC (1656T>A), GGA443GGG (1664A>G), CCA445CCC (1670A>C), GGG446GGA (1673G>A), AAT447AAC (1676T>C), TTT448TTC (1679T>C), CTT449ATC (1680C>A 1682T>C), AGC451AAC (1687G>A), AGA452AGG (1691A>G), ACA456TCA (1701A>T), CCA458CCG (1709A>G), GAA460GCA (1714A>C), AGC462AAC (1720G>A), AGG464GGG (1725A>G), TCT465TTC (1729C>T 1730T>C), GGG466AGG (1731G>A), GTA467GAG (1735T>A 1736A>G), ACA470ACC (1745A>C), ACT471del (1746_1748delACT), CCC472CCA (1751C>A), CCT473GCT (1752C>G), CAG474CCG (1756A>C), CCG478CAG (1768C>A), ATA479AAA (1771T>A), AAG481GAG (1776A>G), GAA482GGA (1780A>G), TAT484TAC (1787T>C), CCT485_TTA486insCCC (1790_1791insCCC), ACT487GCT (1794A>G), AGG490AAA (1804G>A 1805G>A), TCG498TAG (1828C>A)
1193100%126686.4%193 (100%)162 (83.9%)0/0/0/01
Protein mutations:R19N (4642G>A 4643A>C), H27Y (4665C>T), Y30H (4674T>C), V31I (4677G>A), G33K (4683G>A 4684G>A), R36K (4693G>A 4694G>A), Y44F (4717A>T), P47R (4725C>A 4726C>G 4727T>G), R50K (4735G>A), G60E (4765G>A), D61T (4767G>A 4768A>C 4769T>A), R63E (4773A>G 4774G>A), H73L (4804A>T), T74P (4806A>C), K91Q (4857A>C 4859A>G), K92G (4860A>G 4861A>G), S95R (4871C>A), V98I (4878G>A), E101G (4888A>G 4889A>C), L109I (4911C>A 4913G>A), D117E (4937C>A), L124I (4956T>A), I128K (4969T>A), V129I (4971G>A), E134N (4986G>A 4988A>C), A151T (5037G>A), T155A (5049A>G 5051A>T), I159T (5062T>C), T167Q (5085A>C 5086C>A), T170V (5094A>G 5095C>T), K181R (5128A>G)
Codon mutations:CAA12CAG (4622A>G), AGA19AAC (4642G>A 4643A>C), CAC27TAC (4665C>T), TAT30CAT (4674T>C), GTT31ATT (4677G>A), GGG33AAG (4683G>A 4684G>A), GCT35GCC (4691T>C), AGG36AAA (4693G>A 4694G>A), TAT44TTT (4717A>T), CCT47AGG (4725C>A 4726C>G 4727T>G), AGA50AAA (4735G>A), GGG60GAG (4765G>A), GAT61ACA (4767G>A 4768A>C 4769T>A), AGA63GAA (4773A>G 4774G>A), TTG64TTA (4778G>A), TAT69TAC (4793T>C), GGT71GGG (4799T>G), CAT73CTT (4804A>T), ACA74CCA (4806A>C), TTG81CTG (4827T>C), AAA91CAG (4857A>C 4859A>G), AAG92GGG (4860A>G 4861A>G), AGA93AGG (4865A>G), AGC95AGA (4871C>A), GTA98ATA (4878G>A), GAA101GGC (4888A>G 4889A>C), CTA102CTG (4892A>G), CTA106CTG (4904A>G), ATT107ATC (4907T>C), CTG109ATA (4911C>A 4913G>A), TAC111TAT (4919C>T), GAC113GAT (4925C>T), GAC117GAA (4937C>A), GCT119GCC (4943T>C), AGA121AGG (4949A>G), AAG122AAA (4952G>A), TTA124ATA (4956T>A), CAC127CAT (4967C>T), ATA128AAA (4969T>A), GTT129ATT (4971G>A), GAA134AAC (4986G>A 4988A>C), GTA142GTG (5012A>G), TAC147TAT (5027C>T), GCA151ACA (5037G>A), ACA155GCT (5049A>G 5051A>T), ATA159ACA (5062T>C), CCA161CCG (5069A>G), GTT166GTC (5084T>C), ACG167CAG (5085A>C 5086C>A), CTG169CTA (5093G>A), ACA170GTA (5094A>G 5095C>T), GAG171GAA (5099G>A), GAT172GAC (5102T>C), AAG181AGG (5128A>G), CAC187CAT (5147C>T)
197100%68693.1%97 (100%)89 (91.8%)0/0/0/01
Protein mutations:H15Y (5147C>T), E21D (5167G>T), I37P (5213A>C 5214T>C 5215T>G), G41S (5225G>A), E48N (5246G>A 5248A>C), A55E (5268C>A), V83I (5352G>A), A89V (5371C>T 5372A>G)
Codon mutations:CAA8CAG (5128A>G), CAC15TAC (5147C>T), GAG21GAT (5167G>T), ATT37CCG (5213A>C 5214T>C 5215T>G), GGC41AGC (5225G>A), GGG43GGA (5233G>A), GAA48AAC (5246G>A 5248A>C), ACT49ACC (5251T>C), GCA55GAA (5268C>A), GTG57GTT (5275G>T), GAA58GAG (5278A>G), GCC59GCA (5281C>A), AGA62AGG (5290A>G), ATT63ATA (5293T>A), CTG64TTG (5294C>T), CTG67CTA (5305G>A), TGT76TGC (5333T>C), CGA77CGT (5336A>T), GTT83ATT (5352G>A), AGG87AGA (5366G>A), GCA89GTG (5371C>T 5372A>G), GCC93GCT (5384C>T), TAG97TAA (5396G>A)
187100%52775.4%87 (100%)62 (71.3%)0/0/0/00
Protein mutations:P3L (5384C>T), R7N (5396G>A 5397A>T), E9D (5403G>T), K12N (5412G>C), K19T (5432A>C), A21P (5437G>C), N24R (5447A>G 5448T>A), K29Q (5461A>C), Q35Y (5479C>T 5481A>C), V36W (5482G>T 5483T>G 5484T>G), I39T (5492T>C), A42G (5501C>G), R56P (5543G>C), A58T (5548G>A), H59P (5552A>C), N61S (5558A>G), T64I (5567C>T 5568T>A), A67D (5576C>A), S68F (5579C>T), L69V (5581C>G), S70P (5584T>C), T74I (7930C>T 7931C>A), P77A (7938C>G), D80N (7947G>A), *87S (7969A>C)
Codon mutations:CCA3CTA (5384C>T), AGA7AAT (5396G>A 5397A>T), CTA8TTA (5398C>T), GAG9GAT (5403G>T), AAG12AAC (5412G>C), AGT16AGC (5424T>C), AAA19ACA (5432A>C), GCT21CCT (5437G>C), AAT24AGA (5447A>G 5448T>A), TGC25TGT (5451C>T), AAG29CAG (5461A>C), TGC34TGT (5478C>T), CAA35TAC (5479C>T 5481A>C), GTT36TGG (5482G>T 5483T>G 5484T>G), TGT37TGC (5487T>C), TTC38TTT (5490C>T), ATA39ACA (5492T>C), ACA40ACG (5496A>G), AAA41AAG (5499A>G), GCC42GGC (5501C>G), CGA56CCA (5543G>C), GCT58ACT (5548G>A), CAT59CCT (5552A>C), CAG60CAA (5556G>A), AAC61AGC (5558A>G), ACT64ATA (5567C>T 5568T>A), GCT67GAT (5576C>A), TCT68TTT (5579C>T), CTA69GTA (5581C>G), TCA70CCA (5584T>C), ACC74ATA (7930C>T 7931C>A), CCC77GCC (7938C>G), GAC80AAC (7947G>A), TAG87TCG (7969A>C)
1117100%61074.9%117 (100%)87 (74.4%)0/0/0/01
Protein mutations:E10Q (5543G>C), I13L (5552A>C), R14K (5556G>A), T15A (5558A>G), L18Y (5567C>T 5568T>A), L21I (5576C>A), P28Y (7930C>T 7931C>A), N30K (7938C>G), E47A (7988A>C 7989G>A), H53R (8006A>G), S54E (8008T>G 8009C>A), I59F (8023A>T 8025C>T), G61S (8029G>A), T62S (8032A>T), Y63C (8036A>G 8037T>C), S67P (8047T>C), T82H (8092A>C 8093C>A), L83I (8095C>A), D84N (8098G>A), N86S (8105A>G), T91Q (8119A>C 8120C>A 8121T>G), S92G (8122T>G 8123C>G 8124T>G), G93A (8126G>C 8127G>T), T94E (8128A>G 8129C>A), Q95E (8131C>G), P100S (8146C>T), L103S (8156T>C 8157G>T), V104G (8159T>G), P107H (8168C>A 8169T>C), E111G (8180A>G)
Codon mutations:GAA10CAA (5543G>C), GAG11GAA (5548G>A), ATC13CTC (5552A>C), AGA14AAA (5556G>A), ACA15GCA (5558A>G), CTC18TAC (5567C>T 5568T>A), CTT21ATT (5576C>A), CTC22TTG (5579C>T 5581C>G), TAT23TAC (5584T>C), CCT28TAT (7930C>T 7931C>A), AAC30AAG (7938C>G), GGG33GGA (7947G>A), AGA41CGA (7969A>C), AGA43AGG (7977A>G), GAG47GCA (7988A>C 7989G>A), AGA48AGG (7992A>G), CAG49CAA (7995G>A), CAT53CGT (8006A>G), TCG54GAG (8008T>G 8009C>A), AGT56AGC (8016T>C), ATC59TTT (8023A>T 8025C>T), GGC61AGC (8029G>A), ACT62TCT (8032A>T), TAT63TGC (8036A>G 8037T>C), TCT67CCT (8047T>C), GAG69GAA (8055G>A), CCA76CCG (8076A>G), CCG77CCA (8079G>A), ACT82CAT (8092A>C 8093C>A), CTT83ATT (8095C>A), GAT84AAT (8098G>A), TGT85TGC (8103T>C), AAC86AGC (8105A>G), ACT91CAG (8119A>C 8120C>A 8121T>G), TCT92GGG (8122T>G 8123C>G 8124T>G), GGG93GCT (8126G>C 8127G>T), ACG94GAG (8128A>G 8129C>A), CAG95GAG (8131C>G), CCT100TCT (8146C>T), TTG103TCT (8156T>C 8157G>T), GTG104GGG (8159T>G), CCT107CAC (8168C>A 8169T>C), GAG111GGG (8180A>G)
183100%31458.1%82 (98.8%)46 (55.4%)0/1/0/01
Protein mutations:Q2S (5611C>T 5612A>C), P3N (5614C>A 5615C>A), I4L (5617A>T 5619A>G), P5L (5620C>T 5621C>T), I6A (5623A>G 5624T>C), V7I (5626G>A), A8G (5630C>G 5631A>C), V10A (5636T>C), V13I (5644G>A), I16L (5653A>C), A19T (5662G>A), S24T (5677T>A 5679C>T), V26A (5684T>C), I27Y (5686A>T 5687T>A 5688C>T), I33L (5704A>C 5706A>G), L34V (5707T>G), D40N (5725G>A 5727C>T), I43Y (5734A>T 5735T>A), D44K (5737G>A 5739T>A), L46I (5743C>A), I47S (5747T>G 5748A>C), E60D (5787A>T), I61A (5788A>G 5789T>C), S62E (5791T>G 5792C>A 5793A>G), A63E (5795C>A), V65A (5801T>C 5802G>A), E66A (5804A>C 5805G>A), M67L (5806A>C 5808G>T), V69del (5813_5815delTGG), M71V (5818A>G), H73P (5825A>C 5826C>T), H74F (5827C>T 5828A>T), A75I (5830G>A 5831C>T), W77G (5836T>G), V79I (5842G>A), D80N (5845G>A), D81N (5848G>A)
Codon mutations:CAA2TCA (5611C>T 5612A>C), CCT3AAT (5614C>A 5615C>A), ATA4TTG (5617A>T 5619A>G), CCA5TTA (5620C>T 5621C>T), ATA6GCA (5623A>G 5624T>C), GTA7ATA (5626G>A), GCA8GGC (5630C>G 5631A>C), GTA10GCA (5636T>C), GTA13ATA (5644G>A), ATA16CTA (5653A>C), GCA19ACA (5662G>A), TCC24ACT (5677T>A 5679C>T), GTA26GCA (5684T>C), ATC27TAT (5686A>T 5687T>A 5688C>T), ATA33CTG (5704A>C 5706A>G), TTA34GTA (5707T>G), AGA35AGG (5712A>G), GAC40AAT (5725G>A 5727C>T), ATT43TAT (5734A>T 5735T>A), GAT44AAA (5737G>A 5739T>A), CTA46ATA (5743C>A), ATA47AGC (5747T>G 5748A>C), GAA58GAG (5781A>G), GGA59GGG (5784A>G), GAA60GAT (5787A>T), ATA61GCA (5788A>G 5789T>C), TCA62GAG (5791T>G 5792C>A 5793A>G), GCA63GAA (5795C>A), CTT64TTG (5797C>T 5799T>G), GTG65GCA (5801T>C 5802G>A), GAG66GCA (5804A>C 5805G>A), ATG67CTT (5806A>C 5808G>T), GTG69del (5813_5815delTGG), GAG70GAA (5813_5815delTGG 5817G>A), ATG71GTG (5818A>G), CAC73CCT (5825A>C 5826C>T), CAT74TTT (5827C>T 5828A>T), GCT75ATT (5830G>A 5831C>T), TGG77GGG (5836T>G), GAT78GAC (5841T>C), GTT79ATT (5842G>A), GAT80AAT (5845G>A), GAT81AAT (5848G>A), TAG83TAA (5856G>A)
1857100%461776.9%843 (97.9%)632 (73.4%)4/14/0/01
Protein mutations:K4R (5781A>G), E5G (5784A>G), K6M (5787A>T 5788A>G), Y7Q (5789T>C 5791T>G), Q8R (5792C>A 5793A>G), H9N (5795C>A 5797C>T), L10W (5799T>G), W11Q (5801T>C 5802G>A), R12H (5804A>C 5805G>A 5806A>C), W13L (5808G>T), W15del (5813_5815delTGG), R16K (5817G>A 5818A>G), T19L (5825A>C 5826C>T 5827C>T), M20L (5828A>T 5830G>A), L21F (5831C>T), M24T (5841T>C 5842G>A), M26I (5848G>A), S29N (5856G>A), T31A (5861A>G), K33N (5869A>C), A60S (5948G>T), D62E (5956T>A), T63K (5958C>A), V65A (5964T>C), V87E (6030T>A), N92R (6045A>G 6046T>G), K97E (6059A>G), D99N (6065G>A), E106T (6086G>A 6087A>C 6088G>A), S128T (6153G>C), K130D (6158A>G 6160G>T), T132S (6165C>G), D133N (6167G>A 6169T>C), L134I (6170T>A 6172G>T), L134_K135insA (6172_6173insGCC), K135I (6174A>T 6175G>C), D137G (6180A>G 6181T>C), T140D (6188A>G 6189C>A), N141T (6192A>C), S142I (6195G>T), S143A (6197A>G 6198G>C 6199T>C), S144I (6201G>T), G145N (6203G>A 6204G>A 6205G>T), R146D (6206A>G 6207G>A 6208A>C), M147T (6210T>C 6211G>T), I148L (6212A>C 6214A>G), M149K (6216T>A), K151D (6221A>G 6223A>T), G152P (6224G>C 6225G>C), E153_I154insA (6229_6230insGCA), K155Q (6233A>C), I161T (6252T>C 6253C>A), S162T (6255G>C), T163A (6257A>G), S164E (6260A>G 6261G>A 6262C>A), G167D (6270G>A), V169Q (6275G>C 6276T>A), Q170L (6279A>T), E172V (6285A>T), Y173Q (6287T>C 6289T>G), F175L (6293T>C), I182V (6314A>G), P183Q (6318C>A), D185N (6323G>A 6325T>C), N186K (6328T>G), D187_T188insD (6331_6332insGAC), T188N (6333C>A), T189R (6336C>G 6337C>A), S190T (6339G>C 6340C>A), K192R (6345A>G 6346G>A), T194I (6351C>T), S195N (6354G>A), N197D (6359A>G 6361C>T), V200T (6368G>A 6369T>C), F210W (6399T>G 6400T>G), E211D (6403G>T), F223Y (6438T>A), N230E (6458A>G 6460T>G), T232N (6465C>A 6466G>T), N234T (6471A>C 6472T>A), P238S (6482C>T), T240K (6489C>A 6490A>G), R252K (6525G>A 6526G>A), E268G (6573A>G), V270I (6578G>A), V275Q (6593G>C 6594T>A 6595C>A), F277I (6599T>A), T278S (6602A>T 6604G>A), Q287H (6631G>C), T290E (6638A>G 6639C>A), E293Q (6647G>C 6649A>G), R308S (6692C>T 6693G>C), I309L (6695A>T 6697C>A), Q310_R311del (6698_6703delCAGAGA), A316V (6717C>T), V318Y (6722G>T 6723T>A), I320T (6729T>C), K322E (6734A>G), I323_G324insI (6739_6740insATA), N325D (6743A>G 6745T>C), M326I (6748G>C), Q328K (6752C>A 6754A>G), I333V (6767A>G), R335G (6773A>G), A336T (6776G>A), K337Q (6779A>C), N339R (6786A>G 6787T>G), K343A (6797A>G 6798A>C), Q344K (6800C>A), I345V (6803A>G), A346K (6806G>A 6807C>A 6808T>G), S347A (6809A>G 6810G>C 6811C>A), R350G (6818A>G 6820A>G), E351S (6821G>T 6822A>C 6823A>T), Q352Y (6824C>T 6826A>T), G354del (6830_6832delGGA), N355P (6833A>C 6834A>C), K357A (6839A>G 6840A>C), I360K (6849T>A 6850C>A), K362N (6856G>C), Q363S (6857C>T 6858A>C), P369L (6876C>T), V372T (6884G>A 6885T>C), T373R (6888C>G), S375N (6894G>A), G379M (6905G>A 6906G>T 6907A>G), S387T (6929T>A), T388D (6932A>G 6933C>A 6934A>T), Q389E (6935C>G), S393D (6947A>G 6948G>A 6949T>C), W395K (6953T>A 6954G>A 6955G>A), S398_N406del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), N407D (6989A>G), E409G (6996A>G), G410F (6998G>T 6999G>T 7000A>C), S411N (7002G>A), D412G (7005A>G), I424V (7040A>G 7042A>G), K429E (7055A>G), K432R (7064A>C 7065A>G), P437N (7079C>A 7080C>A), S440A (7088A>G 7089G>C 7090T>A), Q442T (7094C>A 7095A>C), R444T (7101G>C 7102A>C), S446N (7106T>A 7107C>A 7108A>C), N460L (7148A>C 7149A>T 7150T>G), S461N (7152G>A 7153C>T), N463T (7158A>C), E464del (7160G>A 7162_7164delGTC), S465N (7162_7164delGTC 7165C>T), D474N (7190G>A), R476K (7197G>A 7198G>A), K490E (7238A>G), R504Q (7280A>C 7281G>A), Q507K (7289C>A), K510R (7299A>G), I515L (7313A>C), M535I (7375G>A), N553S (7428A>G), I580V (7508A>G), I595L (7553A>C), A607N (7589G>A 7590C>A), A612S (7604G>T), Q621E (7631C>G), N624G (7640A>G 7641A>G 7642T>G), H625N (7643C>A), T626M (7647C>T), D632E (7666C>A), R633K (7668G>A), I635V (7673A>G), N636S (7677A>G), T639S (7685A>T), S640K (7689G>A 7690C>A), L641E (7691T>G 7692T>A), H643Y (7697C>T), S644R (7700T>A 7701C>G 7702C>G), E648D (7714A>C), E662A (7755A>C), N674D (7790A>G), T676S (7796A>T), N677Q (7799A>C 7801T>A), L684I (7820T>A), V693I (7847G>A), A700T (7868G>A), Q710K (7898C>A), L721I (7931C>A), T723S (7938C>G), G726E (7947G>A), E736G (7977A>G), R740Q (7988A>C 7989G>A), D741G (7992A>G), R742K (7995G>A), I746V (8006A>G 8008T>G), V749A (8016T>C), S752F (8025C>T), I756A (8036A>G 8037T>C), S762N (8055G>A), H769R (8076A>G), R770H (8079G>A), L774F (8092A>C), L775I (8093C>A 8095C>A), V778A (8103T>C), T779A (8105A>G), E783D (8119A>C), L784R (8120C>A 8121T>G 8122T>G), L785G (8123C>G 8124T>G), G786L (8126G>C 8127G>T 8128A>G), W796L (8156T>C 8157G>T), W797G (8159T>G), L800T (8168C>A 8169T>C), S804G (8180A>G), V812I (8204G>A), G825W (8243G>T), V832A (8265T>C 8266A>T), V833L (8267G>T 8269A>G), G835R (8273G>A), C837G (8279T>G), R841L (8292G>T), H842N (8294C>A), I854A (8330A>G 8331T>C)
Codon mutations:AAG4AGG (5781A>G), GAG5GGG (5784A>G), AAA6ATG (5787A>T 5788A>G), TAT7CAG (5789T>C 5791T>G), CAG8AGG (5792C>A 5793A>G), CAC9AAT (5795C>A 5797C>T), TTG10TGG (5799T>G), TGG11CAG (5801T>C 5802G>A), AGA12CAC (5804A>C 5805G>A 5806A>C), TGG13TTG (5808G>T), TGG15del (5813_5815delTGG), AGA16AAG (5817G>A 5818A>G), ACC19CTT (5825A>C 5826C>T 5827C>T), ATG20TTA (5828A>T 5830G>A), CTC21TTC (5831C>T), CTT22CTG (5836T>G), ATG24ACA (5841T>C 5842G>A), TTG25TTA (5845G>A), ATG26ATA (5848G>A), AGT29AAT (5856G>A), ACA31GCA (5861A>G), AAA33AAC (5869A>C), TTG34TTA (5872G>A), GTC36GTT (5878C>T), AAG46AAA (5908G>A), ACC50ACT (5920C>T), TTT53TTC (5929T>C), GCA60TCA (5948G>T), GAT62GAA (5956T>A), ACA63AAA (5958C>A), GTA65GCA (5964T>C), GTT68GTC (5974T>C), GCC70GCT (5980C>T), GCC73GCT (5989C>T), GAC78GAT (6004C>T), AAC80AAT (6010C>T), GTA85GTT (6025A>T), TTG86CTG (6026T>C), GTA87GAA (6030T>A), GTG89GTA (6037G>A), AAT92AGG (6045A>G 6046T>G), AAC94AAT (6052C>T), AAA97GAA (6059A>G), GAC99AAC (6065G>A), CAG103CAA (6079G>A), GAG106ACA (6086G>A 6087A>C 6088G>A), GTA120GTG (6130A>G), AAA121AAG (6133A>G), AGT128ACT (6153G>C), AAG130GAT (6158A>G 6160G>T), TGC131TGT (6163C>T), ACT132AGT (6165C>G), GAT133AAC (6167G>A 6169T>C), TTG134ATT (6170T>A 6172G>T), TTG134_AAG135insGCC (6172_6173insGCC), AAG135ATC (6174A>T 6175G>C), GAT137GGC (6180A>G 6181T>C), ACT138ACC (6184T>C), ACC140GAC (6188A>G 6189C>A), AAT141ACT (6192A>C), AGT142ATT (6195G>T), AGT143GCC (6197A>G 6198G>C 6199T>C), AGC144ATC (6201G>T), GGG145AAT (6203G>A 6204G>A 6205G>T), AGA146GAC (6206A>G 6207G>A 6208A>C), ATG147ACT (6210T>C 6211G>T), ATA148CTG (6212A>C 6214A>G), ATG149AAG (6216T>A), GAG150GAA (6220G>A), AAA151GAT (6221A>G 6223A>T), GGA152CCA (6224G>C 6225G>C), GAG153_ATA154insGCA (6229_6230insGCA), AAA155CAA (6233A>C), TGC157TGT (6241C>T), ATC161ACA (6252T>C 6253C>A), AGC162ACC (6255G>C), ACA163GCA (6257A>G), AGC164GAA (6260A>G 6261G>A 6262C>A), GGT167GAT (6270G>A), GTG169CAG (6275G>C 6276T>A), CAG170CTG (6279A>T), GAA172GTA (6285A>T), TAT173CAG (6287T>C 6289T>G), TTT175CTT (6293T>C), ATA182GTA (6314A>G), CCA183CAA (6318C>A), ATA184ATC (6322A>C), GAT185AAC (6323G>A 6325T>C), AAT186AAG (6328T>G), GAT187_ACT188insGAC (6331_6332insGAC), ACT188AAT (6333C>A), ACC189AGA (6336C>G 6337C>A), AGC190ACA (6339G>C 6340C>A), TAT191TAC (6343T>C), AAG192AGA (6345A>G 6346G>A), TTG193CTA (6347T>C 6349G>A), ACA194ATA (6351C>T), AGT195AAT (6354G>A), AAC197GAT (6359A>G 6361C>T), GTC200ACC (6368G>A 6369T>C), GCC204GCT (6382C>T), TCC209TCT (6397C>T), TTT210TGG (6399T>G 6400T>G), GAG211GAT (6403G>T), GCC219GCT (6427C>T), CCG220CCA (6430G>A), TTT223TAT (6438T>A), AAA227AAG (6451A>G), AAT230GAG (6458A>G 6460T>G), AAG231AAA (6463G>A), ACG232AAT (6465C>A 6466G>T), AAT234ACA (6471A>C 6472T>A), GGA235GGG (6475A>G), GGA237GGG (6481A>G), CCA238TCA (6482C>T), TGT239TGC (6487T>C), ACA240AAG (6489C>A 6490A>G), AGC243AGT (6499C>T), AGG252AAA (6525G>A 6526G>A), GTA254GTG (6532A>G), TCA256TCC (6538A>C), CTG259TTG (6545C>T), CTG260TTG (6548C>T), AGT264AGC (6562T>C), GAA268GGA (6573A>G), GTA270ATA (6578G>A), ATT272ATC (6586T>C), GTC275CAA (6593G>C 6594T>A 6595C>A), TTC277ATC (6599T>A), ACG278TCA (6602A>T 6604G>A), GAC279GAT (6607C>T), GCT281GCA (6613T>A), GTA286GTG (6628A>G), CAG287CAC (6631G>C), CTG288CTT (6634G>T), AAC289AAT (6637C>T), ACA290GAA (6638A>G 6639C>A), GAA293CAG (6647G>C 6649A>G), ATC307ATA (6691C>A), CGT308TCT (6692C>T 6693G>C), ATC309TTA (6695A>T 6697C>A), CAG310_AGA311del (6698_6703delCAGAGA), GGG314GGA (6712G>A), AGA315CGA (6713A>C), GCA316GTA (6717C>T), GTT318TAT (6722G>T 6723T>A), ATA320ACA (6729T>C), AAA322GAA (6734A>G), ATA323_GGA324insATA (6739_6740insATA), AAT325GAC (6743A>G 6745T>C), ATG326ATC (6748G>C), CAA328AAG (6752C>A 6754A>G), ATT333GTT (6767A>G), AGA335GGA (6773A>G), GCA336ACA (6776G>A), AAA337CAA (6779A>C), AAT339AGG (6786A>G 6787T>G), ACT341ACG (6793T>G), AAA343GCA (6797A>G 6798A>C), CAG344AAG (6800C>A), ATA345GTA (6803A>G), GCT346AAG (6806G>A 6807C>A 6808T>G), AGC347GCA (6809A>G 6810G>C 6811C>A), AAA348AAG (6814A>G), AGA350GGG (6818A>G 6820A>G), GAA351TCT (6821G>T 6822A>C 6823A>T), CAA352TAT (6824C>T 6826A>T), TTT353TTC (6829T>C), GGA354del (6830_6832delGGA), AAT355CCT (6833A>C 6834A>C), AAA357GCA (6839A>G 6840A>C), ATC360AAA (6849T>A 6850C>A), AAG362AAC (6856G>C), CAA363TCA (6857C>T 6858A>C), CCA369CTA (6876C>T), GTA372ACA (6884G>A 6885T>C), ACG373AGG (6888C>G), CAC374CAT (6892C>T), AGT375AAT (6894G>A), GGA379ATG (6905G>A 6906G>T 6907A>G), GGG380GGA (6910G>A), TCA387ACA (6929T>A), ACA388GAT (6932A>G 6933C>A 6934A>T), CAA389GAA (6935C>G), AGT393GAC (6947A>G 6948G>A 6949T>C), ACT394ACA (6952T>A), TGG395AAA (6953T>A 6954G>A 6955G>A), TTT396TTC (6958T>C), AGT398_AAT406del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), AAC407GAC (6989A>G), ACT408ACA (6994T>A), GAA409GGA (6996A>G), GGA410TTC (6998G>T 6999G>T 7000A>C), AGT411AAT (7002G>A), GAC412GGC (7005A>G), ACA413ACT (7009A>T), ACC415ACT (7015C>T), TGC418TGT (7024C>T), AGA419CGA (7025A>C), ATA424GTG (7040A>G 7042A>G), AAA429GAA (7055A>G), GTA430GTG (7060A>G), AAA432CGA (7064A>C 7065A>G), CCT437AAT (7079C>A 7080C>A), ATC439ATT (7087C>T), AGT440GCA (7088A>G 7089G>C 7090T>A), CAA442ACA (7094C>A 7095A>C), ATT443ATC (7099T>C), AGA444ACC (7101G>C 7102A>C), TCA446AAC (7106T>A 7107C>A 7108A>C), GGG451GGT (7123G>T), TTA454TTG (7132A>G), AAT460CTG (7148A>C 7149A>T 7150T>G), AGC461AAT (7152G>A 7153C>T), AAC462AAT (7156C>T), AAT463ACT (7158A>C), GAG464del (7160G>A 7162_7164delGTC), TCC465AAT (7162_7164delGTC 7165C>T), GGA471GGG (7183A>G), GAT474AAT (7190G>A), AGG476AAA (7197G>A 7198G>A), AAA490GAA (7238A>G), TTA494CTA (7250T>C), AAG502AAA (7276G>A), AGA504CAA (7280A>C 7281G>A), CAG507AAG (7289C>A), AAA510AGA (7299A>G), ATA515CTA (7313A>C), TTG518CTG (7322T>C), GCA526GCT (7348A>T), GCA532GCG (7366A>G), GCC533GCG (7369C>G), ATG535ATA (7375G>A), GGT547GGA (7411T>A), CAG550CAA (7420G>A), AAC553AGC (7428A>G), TTG555CTG (7433T>C), GAG560GAA (7450G>A), CAA567CAG (7471A>G), ATC573ATT (7489C>T), AAG574AAA (7492G>A), ATC580GTC (7508A>G), CTG593CTA (7549G>A), ATT595CTT (7553A>C), GGT597GGC (7561T>C), ATT603ATC (7579T>C), GCT607AAT (7589G>A 7590C>A), CCT609CCC (7597T>C), AAT611AAC (7603T>C), GCT612TCT (7604G>T), CTG619CTT (7627G>T), GAA620GAG (7630A>G), CAG621GAG (7631C>G), AAT624GGG (7640A>G 7641A>G 7642T>G), CAC625AAC (7643C>A), ACG626ATG (7647C>T), GAC632GAA (7666C>A), AGA633AAA (7668G>A), GAA634GAG (7672A>G), ATT635GTT (7673A>G), AAC636AGC (7677A>G), ACA639TCA (7685A>T), AGC640AAA (7689G>A 7690C>A), TTA641GAA (7691T>G 7692T>A), CAC643TAC (7697C>T), TCC644AGG (7700T>A 7701C>G 7702C>G), GAA648GAC (7714A>C), CAA650CAG (7720A>G), CAA653CAG (7729A>G), TTG661TTA (7753G>A), GAA662GCA (7755A>C), TTA663TTG (7759A>G), GAT664GAC (7762T>C), TTG669CTG (7775T>C), AAC674GAC (7790A>G), ACA676TCA (7796A>T), AAT677CAA (7799A>C 7801T>A), TTA684ATA (7820T>A), GTA693ATA (7847G>A), GGT694GGC (7852T>C), GCT700ACT (7868G>A), GTA701GTG (7873A>G), GTG705GTA (7885G>A), CAG710AAG (7898C>A), TAT712TAC (7906T>C), CCA714CCT (7912A>T), TTA715TTG (7915A>G), TCG716TCA (7918G>A), CAC720CAT (7930C>T), CTC721ATC (7931C>A), ACC723AGC (7938C>G), GGA726GAA (7947G>A), ATA733ATC (7969A>C), GAA736GGA (7977A>G), AGA740CAA (7988A>C 7989G>A), GAC741GGC (7992A>G), AGA742AAA (7995G>A), ATT746GTG (8006A>G 8008T>G), CGA747AGA (8009C>A), GTG749GCG (8016T>C), GGA751GGT (8023A>T), TCC752TTC (8025C>T), TTG753TTA (8029G>A), GCA754GCT (8032A>T), ATC756GCC (8036A>G 8037T>C), GAT759GAC (8047T>C), AGC762AAC (8055G>A), CAC769CGC (8076A>G), CGC770CAC (8079G>A), TTA774TTC (8092A>C), CTC775ATA (8093C>A 8095C>A), TTG776TTA (8098G>A), GTA778GCA (8103T>C), ACG779GCG (8105A>G), GAA783GAC (8119A>C), CTT784AGG (8120C>A 8121T>G 8122T>G), CTG785GGG (8123C>G 8124T>G), GGA786CTG (8126G>C 8127G>T 8128A>G), CGC787AGG (8129C>A 8131C>G), GCC792GCT (8146C>T), TGG796CTG (8156T>C 8157G>T), TGG797GGG (8159T>G), CTA800ACA (8168C>A 8169T>C), AGT804GGT (8180A>G), AGT810AGC (8200T>C), GTT812ATT (8204G>A), CTC815CTT (8215C>T), GCC819GCA (8227C>A), GGG825TGG (8243G>T), AGG828AGA (8254G>A), GTA832GCT (8265T>C 8266A>T), GTA833TTG (8267G>T 8269A>G), GGA835AGA (8273G>A), TGT837GGT (8279T>G), CGC841CTC (8292G>T), CAC842AAC (8294C>A), ATT854GCT (8330A>G 8331T>C), CTA856TTA (8336C>T)
1190100%97577.3%180 (94.7%)143 (75.3%)0/10/0/01
Protein mutations:K19R (7433T>C), F21L (7428A>G), E40D (7369C>G), K56R (7322T>C), I59S (7313A>C), F64L (7299A>G), C67F (7289C>A), L70C (7280A>C 7281G>A), N80S (7250T>C), F84S (7238A>G), L98F (7197G>A), S100F (7190G>A), D109del (7162_7164delGTC), S110L (7160G>A), L111V (7156C>T 7158A>C), L113F (7150T>G 7152G>A), L114R (7148A>C 7149A>T), S122R (7123G>T), D127E (7108A>C), E128L (7106T>A 7107C>A), H129Q (7102A>C), L130V (7099T>C 7101G>C), C132V (7094C>A 7095A>C), L134A (7087C>T 7088A>G 7089G>C), G137L (7079C>A 7080C>A), F142R (7064A>C 7065A>G), F145S (7055A>G), I150T (7040A>G), L155R (7024C>T 7025A>C), S162P (7005A>G), P164N (6998G>T 6999G>T), S165P (6994T>A 6996A>G), L167S (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT 6989A>G), F168_L176del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), Q179F (6952T>A 6953T>A 6954G>A), L181S (6947A>G 6948G>A), C185S (6934A>T 6935C>G), V186S (6932A>G 6933C>A), E187V (6929T>A)
Codon mutations:AGT6AGC (7471A>G), GCC13GCT (7450G>A), AAA19AGA (7433T>C), TTC21CTC (7428A>G), TGC23TGT (7420G>A), ATA26ATT (7411T>A), GTC38GTT (7375G>A), GAG40GAC (7369C>G), GCT41GCC (7366A>G), CCT47CCA (7348A>T), AAA56AGA (7322T>C), ATT59AGT (7313A>C), TTT64CTT (7299A>G), TGC67TTC (7289C>A), CTT70TGT (7280A>C 7281G>A), CTC71CTT (7276G>A), AAT80AGT (7250T>C), TTT84TCT (7238A>G), TCC97TCT (7198G>A), CTC98TTC (7197G>A), TCT100TTT (7190G>A), CCT102CCC (7183A>G), TCG108TCA (7165C>T), GAC109del (7162_7164delGTC), TCA110TTA (7160G>A), TTG111GTA (7156C>T 7158A>C), TTG112TTA (7153C>T), CTA113TTC (7150T>G 7152G>A), TTA114AGA (7148A>C 7149A>T), GTT119GTC (7132A>G), AGC122AGA (7123G>T), GAT127GAG (7108A>C), GAA128TTA (7106T>A 7107C>A), CAT129CAG (7102A>C), CTA130GTG (7099T>C 7101G>C), TGT132GTT (7094C>A 7095A>C), CCA133CCT (7090T>A), CTG134GCA (7087C>T 7088A>G 7089G>C), GGG137TTG (7079C>A 7080C>A), TTT142CGT (7064A>C 7065A>G), CCT143CCC (7060A>G), TTC145TCC (7055A>G), TTT149TTC (7042A>G), ATA150ACA (7040A>G), CTG155CGA (7024C>T 7025A>C), AGG158AGA (7015C>T), ATT160ATA (7009A>T), TCA162CCA (7005A>G), CTT163TTG (7000A>C 7002G>A), CCT164AAT (6998G>T 6999G>T), TCA165CCT (6994T>A 6996A>G), TTA167TCA (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT 6989A>G), TTT168_CTA176del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), TTA177TTG (6958T>C), AAC178AAT (6955G>A), CAA179TTT (6952T>A 6953T>A 6954G>A), GTA180GTG (6949T>C), CTA181TCA (6947A>G 6948G>A), TGT185TCA (6934A>T 6935C>G), GTT186TCT (6932A>G 6933C>A), GAA187GTA (6929T>A)
119091.8%110279.9%190 (100%)142 (74.7%)0/0/0/00
Protein mutations:V10I (8370G>A 8372G>A), I11V (8373A>G), T15A (8385A>G), V16I (8388G>A), M20L (8400A>C), A23T (8409G>A 8411T>C), E24P (8412G>C 8413A>C 8414G>T), D28E (8426T>G), R29G (8427A>G), A33V (8440C>T 8441A>G), R35Q (8446G>A), K39R (8458A>G), H40R (8461A>G 8462T>G), A49R (8487G>A 8488C>G), T51N (8494C>A 8495C>T), A53P (8499G>C), A54D (8503C>A 8504T>C), C55L (8506G>T 8507T>G), E64D (8534G>C), T71R (8554C>G), A83G (8590C>G), H102Y (8646C>T), Q104K (8652C>A 8654A>G), R105K (8656G>A), D108E (8666T>G), I114V (8682A>G), *124W (8713A>G), V133I (8739G>A), F139M (8757T>A 8759T>G), Y143F (8770A>T), E149D (8789G>C), D151E (8795T>G), K152E (8796A>G), I153V (8799A>G), E155K (8805G>A), K158E (8814A>G), T162N (8827C>A), S163C (8829A>T), V168M (8844G>A), L170Q (8851T>A 8852G>A), D174E (8864T>G), P176E (8868C>G 8869C>A 8870G>A), E177D (8873G>C), R178K (8875G>A), E182K (8886G>A), R184E (8892A>G 8893G>A), S187G (8901A>G)
Codon mutations:GTG10ATA (8370G>A 8372G>A), ATT11GTT (8373A>G), ACT15GCT (8385A>G), GTA16ATA (8388G>A), ATG20CTG (8400A>C), GCT23ACC (8409G>A 8411T>C), GAG24CCT (8412G>C 8413A>C 8414G>T), GAT28GAG (8426T>G), AGG29GGG (8427A>G), GCA33GTG (8440C>T 8441A>G), CGA35CAA (8446G>A), CTG37TTA (8451C>T 8453G>A), AAA39AGA (8458A>G), CAT40CGG (8461A>G 8462T>G), GGA41GGG (8465A>G), ATC43ATT (8471C>T), AGT45AGC (8477T>C), ACA48ACT (8486A>T), GCA49AGA (8487G>A 8488C>G), ACC51AAT (8494C>A 8495C>T), GCT53CCT (8499G>C), GCT54GAC (8503C>A 8504T>C), TGT55TTG (8506G>T 8507T>G), CTA58CTG (8516A>G), GAG63GAA (8531G>A), GAG64GAC (8534G>C), GAG65GAA (8537G>A), GTG66GTA (8540G>A), GGT67GGC (8543T>C), ACA71AGA (8554C>G), ACT80ACC (8582T>C), TAC81TAT (8585C>T), GCA83GGA (8590C>G), CTT87CTC (8603T>C), AGC88AGT (8606C>T), CTA100TTA (8640C>T), CAC102TAC (8646C>T), CAA104AAG (8652C>A 8654A>G), AGA105AAA (8656G>A), GAT108GAG (8666T>G), ATC114GTC (8682A>G), TAG124TGG (8713A>G), GTC133ATC (8739G>A), TTT139ATG (8757T>A 8759T>G), GGA140GGG (8762A>G), TAC143TTC (8770A>T), GAG149GAC (8789G>C), GAT151GAG (8795T>G), AAG152GAG (8796A>G), ATA153GTA (8799A>G), GAG155AAG (8805G>A), AAA158GAA (8814A>G), ACC162AAC (8827C>A), AGC163TGC (8829A>T), TTA165CTA (8835T>C), GTG168ATG (8844G>A), CTG170CAA (8851T>A 8852G>A), GGG172GGA (8858G>A), GAT174GAG (8864T>G), GAC175GAT (8867C>T), CCG176GAA (8868C>G 8869C>A 8870G>A), GAG177GAC (8873G>C), AGA178AAA (8875G>A), TTA181CTG (8883T>C 8885A>G), GAG182AAG (8886G>A), AGG184GAG (8892A>G 8893G>A), AGC187GGC (8901A>G), CTA189TTG (8907C>T 8909A>G)
Proteins
11436100%924792.1%1431 (99.6%)1287 (89.6%)1/5/0/01
Protein mutations:E12K (369G>A), R15A (378C>G 379G>C 380A>T), K30R (424A>G), I34L (435A>C), V46L (471G>C), N47D (474A>G), Q59K (510C>A), L61I (516C>A 518G>A), R76K (562G>A), V82I (579G>A), T84V (585A>G 586C>T), C87Y (595G>A), R91K (607G>A), I92V (609A>G), I94V (615A>G), D102E (641C>G), I104L (645A>C), S111G (666A>G), K112R (669A>C 670A>G), K113Q (672A>C), A115T (678G>A), A119T (690G>A 692A>T), D121E (698C>A), T122K (700C>A), H124_Q127del (705_716delCACAGCAATCAG), I138L (747A>C 749C>T), A146S (771G>T 773C>T), I147L (774A>T), V159I (810G>A), E203D (944G>C), V215L (978G>T 980G>A), V218T (987G>A 988T>C 989G>A), H219Q (992T>G), A224P (1005G>C 1007A>C), M228I (1019G>A), G248Q (1077G>C 1078G>A), N252G (1089A>G 1090A>G 1091T>C), I256V (1101A>G), T280V (1173A>G 1174C>T), Y301F (1237A>T), S310T (1263T>A), N315G (1278A>G 1279A>G), E319D (1292A>C), A340G (1354C>G), G357S (1404G>A), V370A (1444T>C), S373T (1452T>A), T375A (1458A>G 1460C>A), R380K (1474G>A), G381S (1476G>A 1478C>T), R384K (1486G>A), N385G (1488A>G 1489A>G), K388R (1498A>G 1499G>A), T401I (1537C>T), R403K (1543G>A), K418R (1588A>G 1589G>A), D437N (1643G>A), L441Q (1656T>A), K444E (1664A>G), E447K (1673G>A), F448L (1676T>C), S449H (1679T>C 1680C>A), S450P (1682T>C), T453A (1691A>G), N456I (1701A>T), T459A (1709A>G), R460S (1714A>C), Q464R (1725A>G), W466Q (1730T>C 1731G>A), R468G (1736A>G), N471del (1745A>C 1746_1748delACT), S472P (1746_1748delACT), P473S (1751C>A 1752C>G), D479E (1771T>A), Q481R (1776A>G), S485P (1787T>C), S485_F486insS (1790_1791insCCC), F486L (1790_1791insCCC), N487S (1794A>G), V491I (1805G>A), K502R (1839A>G 1840G>A), I503V (1841A>G), E523D (1903A>C), M524I (1906G>A), S525N (1908G>A), R529K (1920G>A), R545K (1968G>A), Q549S (1979C>A 1980A>G 1981G>C), K558R (2007A>G 2008A>G), L577M (2063C>A), V622T (2198G>A 2199T>C), T626M (2211C>T 2212A>G), E709K (2459G>A 2461A>G), I722T (2499T>C 2500A>C), I729V (2519A>G), S749Y (2579A>T 2580G>A), E756D (2602G>T), K760A (2612A>G 2613A>C), Q761K (2615C>A), Q794E (2714C>G), R798K (2727G>A 2728G>A), V832Q (2828G>C 2829T>A 2830G>A), E835D (2839A>C), R864K (2925G>A 2926G>A), T873A (2951A>G), E878D (2968A>C), V879I (2969G>A), I880V (2972A>G 2974A>G), E884T (2984G>A 2985A>C), V904A (3045T>C 3046G>A), R943K (3162G>A), G946S (3170G>T 3171G>C), T963S (3221A>T 3223C>T), T964L (3224A>C 3225C>T), K977R (3264A>G), Q981L (3275C>T 3276A>T), E986D (3292A>T), K1018T (3387A>C), A1033S (3431G>T), L1039K (3449T>A 3450T>A), N1047D (3473A>G 3475T>C), V1053A (3492T>C 3493T>G), T1055S (3497A>T), D1058E (3508C>G), T1064A (3524A>G), Y1070Q (3542T>C 3544T>G), L1078S (3567T>C), Q1099K (3629C>A 3631A>G), A1121S (3695G>T), D1157E (3805T>G), S1164N (3825G>A 3826T>C), L1175I (3857C>A 3859G>A), P1177A (3863C>G), V1219I (3989G>A), I1231L (4025A>C), S1266T (4131G>C), G1270S (4142G>A), R1274K (4155G>A), K1283Q (4181A>C), V1312I (4268G>A), V1348I (4376G>A), K1358R (4407A>G), T1365I (4428C>T), N1379D (4469A>G 4471T>C), L1381V (4475C>G), D1403E (4543C>A), S1430G (4622A>G)
Codon mutations:GAA12AAA (369G>A), CGA15GCT (378C>G 379G>C 380A>T), CCA23CCG (404A>G), AAA30AGA (424A>G), TTA31CTA (426T>C), ATA34CTA (435A>C), TTC44TTT (467C>T), GTT46CTT (471G>C), AAT47GAT (474A>G), CCT48CCA (479T>A), CTG50CTT (485G>T), TTA51CTA (486T>C), AGA58CGA (507A>C), CAA59AAA (510C>A), CTG61ATA (516C>A 518G>A), CTA64TTA (525C>T), GAA74GAG (557A>G), CTT75CTC (560T>C), AGA76AAA (562G>A), GTA82ATA (579G>A), ACC84GTC (585A>G 586C>T), TGT87TAT (595G>A), GTG88GTA (599G>A), AGG91AAG (607G>A), ATA92GTA (609A>G), ATA94GTA (615A>G), GAA99GAG (632A>G), GAC102GAG (641C>G), ATA104CTA (645A>C), GAG107GAA (656G>A), AGT111GGT (666A>G), AAG112CGG (669A>C 670A>G), AAA113CAA (672A>C), AAA114AAG (677A>G), GCA115ACA (678G>A), GCA118GCG (689A>G), GCA119ACT (690G>A 692A>T), GAC121GAA (698C>A), ACA122AAA (700C>A), GGA123GGG (704A>G), CAC124_CAG127del (705_716delCACAGCAATCAG), AGC129AGT (722C>T), GTG135GTA (740G>A), AAC137AAT (746C>T), ATC138CTT (747A>C 749C>T), GGG140GGA (755G>A), CAT144CAC (767T>C), GCC146TCT (771G>T 773C>T), ATA147TTA (774A>T), AAA157AAG (806A>G), GTA158GTG (809A>G), GTA159ATA (810G>A), TTC164TTT (827C>T), AGC165AGT (830C>T), GTG168GTA (839G>A), GGA178GGG (869A>G), ACC180ACT (875C>T), CTA188TTA (897C>T), AAC189AAT (902C>T), GAG203GAC (944G>C), GAT213GAC (974T>C), GTG215TTA (978G>T 980G>A), GTG218ACA (987G>A 988T>C 989G>A), CAT219CAG (992T>G), GGG221GGA (998G>A), CCT222CCC (1001T>C), ATT223ATC (1004T>C), GCA224CCC (1005G>C 1007A>C), GGC226GGT (1013C>T), ATG228ATA (1019G>A), AGA229AGG (1022A>G), CCA231CCT (1028A>T), GAC235GAT (1040C>T), GCA237GCT (1046A>T), GGA248CAA (1077G>C 1078G>A), AAT252GGC (1089A>G 1090A>G 1091T>C), AAT253AAC (1094T>C), ATC256GTC (1101A>G), GTA258GTG (1109A>G), ATT261ATA (1118T>A), ATA266ATC (1133A>C), CTG268CTA (1139G>A), ACC280GTC (1173A>G 1174C>T), CTG283TTG (1182C>T), GGA288GGG (1199A>G), AAG290AAA (1205G>A), CGG299AGG (1230C>A), TAT301TTT (1237A>T), ACT303ACC (1244T>C), GCC306GCT (1253C>T), TCA310ACA (1263T>A), GAG312GAA (1271G>A), AAA314AAG (1277A>G), AAT315GGT (1278A>G 1279A>G), GAA319GAC (1292A>C), ACT332ACC (1331T>C), GCG340GGG (1354C>G), GTA353GTG (1394A>G), CCC356CCT (1403C>T), GGC357AGC (1404G>A), GAA365GAG (1430A>G), GTA370GCA (1444T>C), TCA373ACA (1452T>A), ACC375GCA (1458A>G 1460C>A), AGA380AAA (1474G>A), GGC381AGT (1476G>A 1478C>T), AAT382AAC (1481T>C), AGG384AAG (1486G>A), AAC385GGC (1488A>G 1489A>G), AAG388AGA (1498A>G 1499G>A), AAG391AAA (1508G>A), TGT392TGC (1511T>C), TTC393TTT (1514C>T), GGG399GGA (1532G>A), ACA401ATA (1537C>T), AGA403AAA (1543G>A), AGG409AGA (1562G>A), AAG418AGA (1588A>G 1589G>A), GAT425GAC (1610T>C), TGT426TGC (1613T>C), GAG428GAA (1619G>A), GAT437AAT (1643G>A), CTG438TTG (1646C>T), CTA441CAA (1656T>A), AAG444GAG (1664A>G), AGG446CGG (1670A>C), GAA447AAA (1673G>A), TTT448CTT (1676T>C), TCT449CAT (1679T>C 1680C>A), TCA450CCA (1682T>C), GAG451GAA (1687G>A), ACC453GCC (1691A>G), AAC456ATC (1701A>T), ACC459GCC (1709A>G), AGA460AGC (1714A>C), GAG462GAA (1720G>A), CAG464CGG (1725A>G), GTC465GTT (1729C>T), TGG466CAG (1730T>C 1731G>A), GGT467GGA (1735T>A), AGA468GGA (1736A>G), AAC471del (1745A>C 1746_1748delACT), TCC472CCC (1746_1748delACT), CCC473AGC (1751C>A 1752C>G), TCA474TCC (1756A>C), GCC478GCA (1768C>A), GAT479GAA (1771T>A), CAA481CGA (1776A>G), GGA482GGG (1780A>G), TCC485CCC (1787T>C), TCC485_TTT486insTCC (1790_1791insCCC), TTT486CTT (1790_1791insCCC), AAC487AGC (1794A>G), CAG490CAA (1804G>A), GTC491ATC (1805G>A), CTC498CTA (1828C>A), AAG502AGA (1839A>G 1840G>A), ATA503GTA (1841A>G), GGG505GGA (1849G>A), CAA506CAG (1852A>G), GAA523GAC (1903A>C), ATG524ATA (1906G>A), AGT525AAT (1908G>A), AGA529AAA (1920G>A), AGA545AAA (1968G>A), CAG549AGC (1979C>A 1980A>G 1981G>C), ATC554ATT (1996C>T), CAT557CAC (2005T>C), AAA558AGG (2007A>G 2008A>G), GTA563GTG (2023A>G), ACA568ACG (2038A>G), CTG577ATG (2063C>A), ACT579ACC (2071T>C), TGC583TGT (2083C>T), CCC588CCA (2098C>A), AGC590AGT (2104C>T), TTA599TTG (2131A>G), AAA607AAG (2155A>G), GCA620GCT (2194A>T), GTA622ACA (2198G>A 2199T>C), ATT624ATA (2206T>A), ACA626ATG (2211C>T 2212A>G), GAG627GAA (2215G>A), AAG630AAA (2224G>A), GGG632GGA (2230G>A), AGA659AGG (2311A>G), AAG669AAA (2341G>A), GAC673GAT (2353C>T), TTC674TTT (2356C>T), GAA676GAG (2362A>G), CCA682CCG (2380A>G), CCC684CCA (2386C>A), AAA691AAG (2407A>G), GGT699GGG (2431T>G), CCC706CCT (2452C>T), GAA709AAG (2459G>A 2461A>G), GAC710GAT (2464C>T), TAT714TAC (2476T>C), TTT717TTC (2485T>C), ATA722ACC (2499T>C 2500A>C), GGG728GGA (2518G>A), ATT729GTT (2519A>G), AGA730AGG (2524A>G), TAT731TAC (2527T>C), CAG738CAA (2548G>A), AGT749TAT (2579A>T 2580G>A), GAG756GAT (2602G>T), CCT757CCC (2605T>C), AAA760GCA (2612A>G 2613A>C), CAA761AAA (2615C>A), TAT768TAC (2638T>C), GGA777GGG (2665A>G), GGG783GGA (2683G>A), GAG790GAA (2704G>A), CTG792TTA (2708C>T 2710G>A), CAA794GAA (2714C>G), CTG796CTA (2722G>A), TTG797CTG (2723T>C), AGG798AAA (2727G>A 2728G>A), CTT801TTA (2735C>T 2737T>A), ACC802ACT (2740C>T), CAG809CAA (2761G>A), CCT812CCC (2770T>C), GGT818GGG (2788T>G), GTA828GTG (2818A>G), GTG832CAA (2828G>C 2829T>A 2830G>A), CTG833TTG (2831C>T), GAA835GAC (2839A>C), AAA836AAG (2842A>G), GAC843GAT (2863C>T), GTG848GTA (2878G>A), GGG849GGA (2881G>A), TTG851CTA (2885T>C 2887G>A), TAC858TAT (2908C>T), AGG864AAA (2925G>A 2926G>A), AGA871AGG (2947A>G), ACC873GCC (2951A>G), AAA874AAG (2956A>G), GAA878GAC (2968A>C), GTA879ATA (2969G>A), ATA880GTG (2972A>G 2974A>G), CTA882CTG (2980A>G), ACA883ACT (2983A>T), GAA884ACA (2984G>A 2985A>C), CTA888TTA (2996C>T), CTG890TTG (3002C>T), GAA892GAG (3010A>G), AAC893AAT (3013C>T), AGA894AGG (3016A>G), GGA903GGG (3043A>G), GTG904GCA (3045T>C 3046G>A), CCA908CCG (3058A>G), AAG918AAA (3088G>A), CAG919CAA (3091G>A), GGC922GGG (3100C>G), CTG936CTA (3142G>A), AAA940AAG (3154A>G), AGA943AAA (3162G>A), GGT946TCT (3170G>T 3171G>C), CAA954CAG (3196A>G), GAG957GAA (3205G>A), AAA961AAG (3217A>G), ACC963TCT (3221A>T 3223C>T), ACA964CTA (3224A>C 3225C>T), GGA971GGC (3247A>C), AAA975AAG (3259A>G), AAA977AGA (3264A>G), CTG978CTA (3268G>A), CAA981TTA (3275C>T 3276A>T), AAG982AAA (3280G>A), GAA983GAG (3283A>G), GAA986GAT (3292A>T), TAT992TAC (3310T>C), GTT1004GTC (3346T>C), CCT1007CCC (3355T>C), CCC1008CCT (3358C>T), TTA1009CTA (3359T>C), GTG1010GTA (3364G>A), TTA1012CTA (3368T>C), TAC1014TAT (3376C>T), GAG1017GAA (3385G>A), AAA1018ACA (3387A>C), GAA1019GAG (3391A>G), GCT1033TCT (3431G>T), AAC1034AAT (3436C>T), AGG1035AGA (3439G>A), ACT1037ACC (3445T>C), TTA1039AAA (3449T>A 3450T>A), AAT1047GAC (3473A>G 3475T>C), GTT1053GCG (3492T>C 3493T>G), ACC1055TCC (3497A>T), GAC1058GAG (3508C>G), ACA1059ACT (3511A>T), ACT1064GCT (3524A>G), TAT1070CAG (3542T>C 3544T>G), CTA1071TTA (3545C>T), TTG1073TTA (3553G>A), TCG1076TCA (3562G>A), TTA1078TCA (3567T>C), CAA1087CAG (3595A>G), CAA1099AAG (3629C>A 3631A>G), CAG1111CAA (3667G>A), TAT1119TAC (3691T>C), GCA1121TCA (3695G>T), GGA1128GGG (3718A>G), CTA1147CTG (3775A>G), GGA1151GGG (3787A>G), GCC1155GCA (3799C>A), CAA1156CAG (3802A>G), GAT1157GAG (3805T>G), GAG1160GAA (3814G>A), AGT1164AAC (3825G>A 3826T>C), AAC1174AAT (3856C>T), CTG1175ATA (3857C>A 3859G>A), CCT1177GCT (3863C>G), GCC1185GCT (3889C>T), GGA1194GGG (3916A>G), GAC1202GAT (3940C>T), AGT1204AGC (3946T>C), GGA1206GGG (3952A>G), CTA1210TTA (3962C>T), GTT1219ATT (3989G>A), GTT1224GTC (4006T>C), GCC1227GCT (4015C>T), GGA1229GGG (4021A>G), TAT1230TAC (4024T>C), ATA1231CTA (4025A>C), ATT1236ATC (4042T>C), GGG1241GGA (4057G>A), CAG1242CAA (4060G>A), GAA1243GAG (4063A>G), GCA1245GCC (4069A>C), TAT1246TAC (4072T>C), TTT1247TTC (4075T>C), CTT1248CTA (4078T>A), TTA1249CTA (4079T>C), AAA1250AAG (4084A>G), ACT1262ACA (4120T>A), AGC1266ACC (4131G>C), GGT1270AGT (4142G>A), GCT1271GCC (4147T>C), AGG1274AAG (4155G>A), GCC1275GCA (4159C>A), GCC1276GCT (4162C>T), GCG1280GCA (4174G>A), GGA1281GGT (4177A>T), AAG1283CAG (4181A>C), CCC1289CCT (4201C>T), AAT1291AAC (4207T>C), ATT1308ATC (4258T>C), GTA1312ATA (4268G>A), GAT1314GAC (4276T>C), CAG1315CAA (4279G>A), GTA1323GTC (4303A>C), ATC1329ATT (4321C>T), GGG1340GGA (4354G>A), GTA1348ATA (4376G>A), AAA1358AGA (4407A>G), ACA1365ATA (4428C>T), TTT1370TTC (4444T>C), AAT1379GAC (4469A>G 4471T>C), CTT1381GTT (4475C>G), CTC1388CTA (4498C>A), GTA1397GTC (4525A>C), GAT1400GAC (4534T>C), GAC1403GAA (4543C>A), AAA1405AAG (4549A>G), GTG1407GTT (4555G>T), AGT1430GGT (4622A>G), TAG1436TAA (4642G>A)
156100%22058.5%55 (96.5%)34 (59.6%)1/1/0/00
Protein mutations:D5N (1643G>A), L9Q (1656T>A), K12E (1664A>G), E15K (1673G>A), F16L (1676T>C), S17H (1679T>C 1680C>A), S18P (1682T>C), T21A (1691A>G), N24I (1701A>T), T27A (1709A>G), R28S (1714A>C), Q32R (1725A>G), W34Q (1730T>C 1731G>A), R36G (1736A>G), N39del (1745A>C 1746_1748delACT), S40P (1746_1748delACT), P41S (1751C>A 1752C>G), D47E (1771T>A), Q49R (1776A>G), S53P (1787T>C), S53_F54insS (1790_1791insCCC), F54L (1790_1791insCCC), N55S (1794A>G)
Codon mutations:GAT5AAT (1643G>A), CTG6TTG (1646C>T), CTA9CAA (1656T>A), AAG12GAG (1664A>G), AGG14CGG (1670A>C), GAA15AAA (1673G>A), TTT16CTT (1676T>C), TCT17CAT (1679T>C 1680C>A), TCA18CCA (1682T>C), GAG19GAA (1687G>A), ACC21GCC (1691A>G), AAC24ATC (1701A>T), ACC27GCC (1709A>G), AGA28AGC (1714A>C), GAG30GAA (1720G>A), CAG32CGG (1725A>G), GTC33GTT (1729C>T), TGG34CAG (1730T>C 1731G>A), GGT35GGA (1735T>A), AGA36GGA (1736A>G), AAC39del (1745A>C 1746_1748delACT), TCC40CCC (1746_1748delACT), CCC41AGC (1751C>A 1752C>G), TCA42TCC (1756A>C), GCC46GCA (1768C>A), GAT47GAA (1771T>A), CAA49CGA (1776A>G), GGA50GGG (1780A>G), TCC53CCC (1787T>C), TCC53_TTT54insTCC (1790_1791insCCC), TTT54CTT (1790_1791insCCC), AAC55AGC (1794A>G)
1995100%651193.0%994 (99.8%)906 (91.0%)1/1/0/00
Protein mutations:L1Q (1656T>A), K4E (1664A>G), E7K (1673G>A), F8L (1676T>C), S9H (1679T>C 1680C>A), S10P (1682T>C), T13A (1691A>G), N16I (1701A>T), T19A (1709A>G), R20S (1714A>C), Q24R (1725A>G), W26Q (1730T>C 1731G>A), R28G (1736A>G), N31del (1745A>C 1746_1748delACT), S32P (1746_1748delACT), P33S (1751C>A 1752C>G), D39E (1771T>A), Q41R (1776A>G), S45P (1787T>C), S45_F46insS (1790_1791insCCC), F46L (1790_1791insCCC), N47S (1794A>G), V51I (1805G>A), K62R (1839A>G 1840G>A), I63V (1841A>G), E83D (1903A>C), M84I (1906G>A), S85N (1908G>A), R89K (1920G>A), R105K (1968G>A), Q109S (1979C>A 1980A>G 1981G>C), K118R (2007A>G 2008A>G), L137M (2063C>A), V182T (2198G>A 2199T>C), T186M (2211C>T 2212A>G), E269K (2459G>A 2461A>G), I282T (2499T>C 2500A>C), I289V (2519A>G), S309Y (2579A>T 2580G>A), E316D (2602G>T), K320A (2612A>G 2613A>C), Q321K (2615C>A), Q354E (2714C>G), R358K (2727G>A 2728G>A), V392Q (2828G>C 2829T>A 2830G>A), E395D (2839A>C), R424K (2925G>A 2926G>A), T433A (2951A>G), E438D (2968A>C), V439I (2969G>A), I440V (2972A>G 2974A>G), E444T (2984G>A 2985A>C), V464A (3045T>C 3046G>A), R503K (3162G>A), G506S (3170G>T 3171G>C), T523S (3221A>T 3223C>T), T524L (3224A>C 3225C>T), K537R (3264A>G), Q541L (3275C>T 3276A>T), E546D (3292A>T), K578T (3387A>C), A593S (3431G>T), L599K (3449T>A 3450T>A), N607D (3473A>G 3475T>C), V613A (3492T>C 3493T>G), T615S (3497A>T), D618E (3508C>G), T624A (3524A>G), Y630Q (3542T>C 3544T>G), L638S (3567T>C), Q659K (3629C>A 3631A>G), A681S (3695G>T), D717E (3805T>G), S724N (3825G>A 3826T>C), L735I (3857C>A 3859G>A), P737A (3863C>G), V779I (3989G>A), I791L (4025A>C), S826T (4131G>C), G830S (4142G>A), R834K (4155G>A), K843Q (4181A>C), V872I (4268G>A), V908I (4376G>A), K918R (4407A>G), T925I (4428C>T), N939D (4469A>G 4471T>C), L941V (4475C>G), D963E (4543C>A), S990G (4622A>G)
Codon mutations:CTA1CAA (1656T>A), AAG4GAG (1664A>G), AGG6CGG (1670A>C), GAA7AAA (1673G>A), TTT8CTT (1676T>C), TCT9CAT (1679T>C 1680C>A), TCA10CCA (1682T>C), GAG11GAA (1687G>A), ACC13GCC (1691A>G), AAC16ATC (1701A>T), ACC19GCC (1709A>G), AGA20AGC (1714A>C), GAG22GAA (1720G>A), CAG24CGG (1725A>G), GTC25GTT (1729C>T), TGG26CAG (1730T>C 1731G>A), GGT27GGA (1735T>A), AGA28GGA (1736A>G), AAC31del (1745A>C 1746_1748delACT), TCC32CCC (1746_1748delACT), CCC33AGC (1751C>A 1752C>G), TCA34TCC (1756A>C), GCC38GCA (1768C>A), GAT39GAA (1771T>A), CAA41CGA (1776A>G), GGA42GGG (1780A>G), TCC45CCC (1787T>C), TCC45_TTT46insTCC (1790_1791insCCC), TTT46CTT (1790_1791insCCC), AAC47AGC (1794A>G), CAG50CAA (1804G>A), GTC51ATC (1805G>A), CTC58CTA (1828C>A), AAG62AGA (1839A>G 1840G>A), ATA63GTA (1841A>G), GGG65GGA (1849G>A), CAA66CAG (1852A>G), GAA83GAC (1903A>C), ATG84ATA (1906G>A), AGT85AAT (1908G>A), AGA89AAA (1920G>A), AGA105AAA (1968G>A), CAG109AGC (1979C>A 1980A>G 1981G>C), ATC114ATT (1996C>T), CAT117CAC (2005T>C), AAA118AGG (2007A>G 2008A>G), GTA123GTG (2023A>G), ACA128ACG (2038A>G), CTG137ATG (2063C>A), ACT139ACC (2071T>C), TGC143TGT (2083C>T), CCC148CCA (2098C>A), AGC150AGT (2104C>T), TTA159TTG (2131A>G), AAA167AAG (2155A>G), GCA180GCT (2194A>T), GTA182ACA (2198G>A 2199T>C), ATT184ATA (2206T>A), ACA186ATG (2211C>T 2212A>G), GAG187GAA (2215G>A), AAG190AAA (2224G>A), GGG192GGA (2230G>A), AGA219AGG (2311A>G), AAG229AAA (2341G>A), GAC233GAT (2353C>T), TTC234TTT (2356C>T), GAA236GAG (2362A>G), CCA242CCG (2380A>G), CCC244CCA (2386C>A), AAA251AAG (2407A>G), GGT259GGG (2431T>G), CCC266CCT (2452C>T), GAA269AAG (2459G>A 2461A>G), GAC270GAT (2464C>T), TAT274TAC (2476T>C), TTT277TTC (2485T>C), ATA282ACC (2499T>C 2500A>C), GGG288GGA (2518G>A), ATT289GTT (2519A>G), AGA290AGG (2524A>G), TAT291TAC (2527T>C), CAG298CAA (2548G>A), AGT309TAT (2579A>T 2580G>A), GAG316GAT (2602G>T), CCT317CCC (2605T>C), AAA320GCA (2612A>G 2613A>C), CAA321AAA (2615C>A), TAT328TAC (2638T>C), GGA337GGG (2665A>G), GGG343GGA (2683G>A), GAG350GAA (2704G>A), CTG352TTA (2708C>T 2710G>A), CAA354GAA (2714C>G), CTG356CTA (2722G>A), TTG357CTG (2723T>C), AGG358AAA (2727G>A 2728G>A), CTT361TTA (2735C>T 2737T>A), ACC362ACT (2740C>T), CAG369CAA (2761G>A), CCT372CCC (2770T>C), GGT378GGG (2788T>G), GTA388GTG (2818A>G), GTG392CAA (2828G>C 2829T>A 2830G>A), CTG393TTG (2831C>T), GAA395GAC (2839A>C), AAA396AAG (2842A>G), GAC403GAT (2863C>T), GTG408GTA (2878G>A), GGG409GGA (2881G>A), TTG411CTA (2885T>C 2887G>A), TAC418TAT (2908C>T), AGG424AAA (2925G>A 2926G>A), AGA431AGG (2947A>G), ACC433GCC (2951A>G), AAA434AAG (2956A>G), GAA438GAC (2968A>C), GTA439ATA (2969G>A), ATA440GTG (2972A>G 2974A>G), CTA442CTG (2980A>G), ACA443ACT (2983A>T), GAA444ACA (2984G>A 2985A>C), CTA448TTA (2996C>T), CTG450TTG (3002C>T), GAA452GAG (3010A>G), AAC453AAT (3013C>T), AGA454AGG (3016A>G), GGA463GGG (3043A>G), GTG464GCA (3045T>C 3046G>A), CCA468CCG (3058A>G), AAG478AAA (3088G>A), CAG479CAA (3091G>A), GGC482GGG (3100C>G), CTG496CTA (3142G>A), AAA500AAG (3154A>G), AGA503AAA (3162G>A), GGT506TCT (3170G>T 3171G>C), CAA514CAG (3196A>G), GAG517GAA (3205G>A), AAA521AAG (3217A>G), ACC523TCT (3221A>T 3223C>T), ACA524CTA (3224A>C 3225C>T), GGA531GGC (3247A>C), AAA535AAG (3259A>G), AAA537AGA (3264A>G), CTG538CTA (3268G>A), CAA541TTA (3275C>T 3276A>T), AAG542AAA (3280G>A), GAA543GAG (3283A>G), GAA546GAT (3292A>T), TAT552TAC (3310T>C), GTT564GTC (3346T>C), CCT567CCC (3355T>C), CCC568CCT (3358C>T), TTA569CTA (3359T>C), GTG570GTA (3364G>A), TTA572CTA (3368T>C), TAC574TAT (3376C>T), GAG577GAA (3385G>A), AAA578ACA (3387A>C), GAA579GAG (3391A>G), GCT593TCT (3431G>T), AAC594AAT (3436C>T), AGG595AGA (3439G>A), ACT597ACC (3445T>C), TTA599AAA (3449T>A 3450T>A), AAT607GAC (3473A>G 3475T>C), GTT613GCG (3492T>C 3493T>G), ACC615TCC (3497A>T), GAC618GAG (3508C>G), ACA619ACT (3511A>T), ACT624GCT (3524A>G), TAT630CAG (3542T>C 3544T>G), CTA631TTA (3545C>T), TTG633TTA (3553G>A), TCG636TCA (3562G>A), TTA638TCA (3567T>C), CAA647CAG (3595A>G), CAA659AAG (3629C>A 3631A>G), CAG671CAA (3667G>A), TAT679TAC (3691T>C), GCA681TCA (3695G>T), GGA688GGG (3718A>G), CTA707CTG (3775A>G), GGA711GGG (3787A>G), GCC715GCA (3799C>A), CAA716CAG (3802A>G), GAT717GAG (3805T>G), GAG720GAA (3814G>A), AGT724AAC (3825G>A 3826T>C), AAC734AAT (3856C>T), CTG735ATA (3857C>A 3859G>A), CCT737GCT (3863C>G), GCC745GCT (3889C>T), GGA754GGG (3916A>G), GAC762GAT (3940C>T), AGT764AGC (3946T>C), GGA766GGG (3952A>G), CTA770TTA (3962C>T), GTT779ATT (3989G>A), GTT784GTC (4006T>C), GCC787GCT (4015C>T), GGA789GGG (4021A>G), TAT790TAC (4024T>C), ATA791CTA (4025A>C), ATT796ATC (4042T>C), GGG801GGA (4057G>A), CAG802CAA (4060G>A), GAA803GAG (4063A>G), GCA805GCC (4069A>C), TAT806TAC (4072T>C), TTT807TTC (4075T>C), CTT808CTA (4078T>A), TTA809CTA (4079T>C), AAA810AAG (4084A>G), ACT822ACA (4120T>A), AGC826ACC (4131G>C), GGT830AGT (4142G>A), GCT831GCC (4147T>C), AGG834AAG (4155G>A), GCC835GCA (4159C>A), GCC836GCT (4162C>T), GCG840GCA (4174G>A), GGA841GGT (4177A>T), AAG843CAG (4181A>C), CCC849CCT (4201C>T), AAT851AAC (4207T>C), ATT868ATC (4258T>C), GTA872ATA (4268G>A), GAT874GAC (4276T>C), CAG875CAA (4279G>A), GTA883GTC (4303A>C), ATC889ATT (4321C>T), GGG900GGA (4354G>A), GTA908ATA (4376G>A), AAA918AGA (4407A>G), ACA925ATA (4428C>T), TTT930TTC (4444T>C), AAT939GAC (4469A>G 4471T>C), CTT941GTT (4475C>G), CTC948CTA (4498C>A), GTA957GTC (4525A>C), GAT960GAC (4534T>C), GAC963GAA (4543C>A), AAA965AAG (4549A>G), GTG967GTT (4555G>T), AGT990GGT (4622A>G)
199100%65093.1%99 (100%)88 (88.9%)0/0/0/00
Protein mutations:V3I (1805G>A), K14R (1839A>G 1840G>A), I15V (1841A>G), E35D (1903A>C), M36I (1906G>A), S37N (1908G>A), R41K (1920G>A), R57K (1968G>A), Q61S (1979C>A 1980A>G 1981G>C), K70R (2007A>G 2008A>G), L89M (2063C>A)
Codon mutations:CAG2CAA (1804G>A), GTC3ATC (1805G>A), CTC10CTA (1828C>A), AAG14AGA (1839A>G 1840G>A), ATA15GTA (1841A>G), GGG17GGA (1849G>A), CAA18CAG (1852A>G), GAA35GAC (1903A>C), ATG36ATA (1906G>A), AGT37AAT (1908G>A), AGA41AAA (1920G>A), AGA57AAA (1968G>A), CAG61AGC (1979C>A 1980A>G 1981G>C), ATC66ATT (1996C>T), CAT69CAC (2005T>C), AAA70AGG (2007A>G 2008A>G), GTA75GTG (2023A>G), ACA80ACG (2038A>G), CTG89ATG (2063C>A), ACT91ACC (2071T>C), TGC95TGT (2083C>T)
1560100%371394.7%560 (100%)521 (93.0%)0/0/0/00
Protein mutations:V35T (2198G>A 2199T>C), T39M (2211C>T 2212A>G), E122K (2459G>A 2461A>G), I135T (2499T>C 2500A>C), I142V (2519A>G), S162Y (2579A>T 2580G>A), E169D (2602G>T), K173A (2612A>G 2613A>C), Q174K (2615C>A), Q207E (2714C>G), R211K (2727G>A 2728G>A), V245Q (2828G>C 2829T>A 2830G>A), E248D (2839A>C), R277K (2925G>A 2926G>A), T286A (2951A>G), E291D (2968A>C), V292I (2969G>A), I293V (2972A>G 2974A>G), E297T (2984G>A 2985A>C), V317A (3045T>C 3046G>A), R356K (3162G>A), G359S (3170G>T 3171G>C), T376S (3221A>T 3223C>T), T377L (3224A>C 3225C>T), K390R (3264A>G), Q394L (3275C>T 3276A>T), E399D (3292A>T), K431T (3387A>C), A446S (3431G>T), L452K (3449T>A 3450T>A), N460D (3473A>G 3475T>C), V466A (3492T>C 3493T>G), T468S (3497A>T), D471E (3508C>G), T477A (3524A>G), Y483Q (3542T>C 3544T>G), L491S (3567T>C), Q512K (3629C>A 3631A>G), A534S (3695G>T)
Codon mutations:CCC1CCA (2098C>A), AGC3AGT (2104C>T), TTA12TTG (2131A>G), AAA20AAG (2155A>G), GCA33GCT (2194A>T), GTA35ACA (2198G>A 2199T>C), ATT37ATA (2206T>A), ACA39ATG (2211C>T 2212A>G), GAG40GAA (2215G>A), AAG43AAA (2224G>A), GGG45GGA (2230G>A), AGA72AGG (2311A>G), AAG82AAA (2341G>A), GAC86GAT (2353C>T), TTC87TTT (2356C>T), GAA89GAG (2362A>G), CCA95CCG (2380A>G), CCC97CCA (2386C>A), AAA104AAG (2407A>G), GGT112GGG (2431T>G), CCC119CCT (2452C>T), GAA122AAG (2459G>A 2461A>G), GAC123GAT (2464C>T), TAT127TAC (2476T>C), TTT130TTC (2485T>C), ATA135ACC (2499T>C 2500A>C), GGG141GGA (2518G>A), ATT142GTT (2519A>G), AGA143AGG (2524A>G), TAT144TAC (2527T>C), CAG151CAA (2548G>A), AGT162TAT (2579A>T 2580G>A), GAG169GAT (2602G>T), CCT170CCC (2605T>C), AAA173GCA (2612A>G 2613A>C), CAA174AAA (2615C>A), TAT181TAC (2638T>C), GGA190GGG (2665A>G), GGG196GGA (2683G>A), GAG203GAA (2704G>A), CTG205TTA (2708C>T 2710G>A), CAA207GAA (2714C>G), CTG209CTA (2722G>A), TTG210CTG (2723T>C), AGG211AAA (2727G>A 2728G>A), CTT214TTA (2735C>T 2737T>A), ACC215ACT (2740C>T), CAG222CAA (2761G>A), CCT225CCC (2770T>C), GGT231GGG (2788T>G), GTA241GTG (2818A>G), GTG245CAA (2828G>C 2829T>A 2830G>A), CTG246TTG (2831C>T), GAA248GAC (2839A>C), AAA249AAG (2842A>G), GAC256GAT (2863C>T), GTG261GTA (2878G>A), GGG262GGA (2881G>A), TTG264CTA (2885T>C 2887G>A), TAC271TAT (2908C>T), AGG277AAA (2925G>A 2926G>A), AGA284AGG (2947A>G), ACC286GCC (2951A>G), AAA287AAG (2956A>G), GAA291GAC (2968A>C), GTA292ATA (2969G>A), ATA293GTG (2972A>G 2974A>G), CTA295CTG (2980A>G), ACA296ACT (2983A>T), GAA297ACA (2984G>A 2985A>C), CTA301TTA (2996C>T), CTG303TTG (3002C>T), GAA305GAG (3010A>G), AAC306AAT (3013C>T), AGA307AGG (3016A>G), GGA316GGG (3043A>G), GTG317GCA (3045T>C 3046G>A), CCA321CCG (3058A>G), AAG331AAA (3088G>A), CAG332CAA (3091G>A), GGC335GGG (3100C>G), CTG349CTA (3142G>A), AAA353AAG (3154A>G), AGA356AAA (3162G>A), GGT359TCT (3170G>T 3171G>C), CAA367CAG (3196A>G), GAG370GAA (3205G>A), AAA374AAG (3217A>G), ACC376TCT (3221A>T 3223C>T), ACA377CTA (3224A>C 3225C>T), GGA384GGC (3247A>C), AAA388AAG (3259A>G), AAA390AGA (3264A>G), CTG391CTA (3268G>A), CAA394TTA (3275C>T 3276A>T), AAG395AAA (3280G>A), GAA396GAG (3283A>G), GAA399GAT (3292A>T), TAT405TAC (3310T>C), GTT417GTC (3346T>C), CCT420CCC (3355T>C), CCC421CCT (3358C>T), TTA422CTA (3359T>C), GTG423GTA (3364G>A), TTA425CTA (3368T>C), TAC427TAT (3376C>T), GAG430GAA (3385G>A), AAA431ACA (3387A>C), GAA432GAG (3391A>G), GCT446TCT (3431G>T), AAC447AAT (3436C>T), AGG448AGA (3439G>A), ACT450ACC (3445T>C), TTA452AAA (3449T>A 3450T>A), AAT460GAC (3473A>G 3475T>C), GTT466GCG (3492T>C 3493T>G), ACC468TCC (3497A>T), GAC471GAG (3508C>G), ACA472ACT (3511A>T), ACT477GCT (3524A>G), TAT483CAG (3542T>C 3544T>G), CTA484TTA (3545C>T), TTG486TTA (3553G>A), TCG489TCA (3562G>A), TTA491TCA (3567T>C), CAA500CAG (3595A>G), CAA512AAG (3629C>A 3631A>G), CAG524CAA (3667G>A), TAT532TAC (3691T>C), GCA534TCA (3695G>T), GGA541GGG (3718A>G), CTA560CTG (3775A>G)
1440100%302295.4%440 (100%)412 (93.6%)0/0/0/00
Protein mutations:V35T (2198G>A 2199T>C), T39M (2211C>T 2212A>G), E122K (2459G>A 2461A>G), I135T (2499T>C 2500A>C), I142V (2519A>G), S162Y (2579A>T 2580G>A), E169D (2602G>T), K173A (2612A>G 2613A>C), Q174K (2615C>A), Q207E (2714C>G), R211K (2727G>A 2728G>A), V245Q (2828G>C 2829T>A 2830G>A), E248D (2839A>C), R277K (2925G>A 2926G>A), T286A (2951A>G), E291D (2968A>C), V292I (2969G>A), I293V (2972A>G 2974A>G), E297T (2984G>A 2985A>C), V317A (3045T>C 3046G>A), R356K (3162G>A), G359S (3170G>T 3171G>C), T376S (3221A>T 3223C>T), T377L (3224A>C 3225C>T), K390R (3264A>G), Q394L (3275C>T 3276A>T), E399D (3292A>T), K431T (3387A>C)
Codon mutations:CCC1CCA (2098C>A), AGC3AGT (2104C>T), TTA12TTG (2131A>G), AAA20AAG (2155A>G), GCA33GCT (2194A>T), GTA35ACA (2198G>A 2199T>C), ATT37ATA (2206T>A), ACA39ATG (2211C>T 2212A>G), GAG40GAA (2215G>A), AAG43AAA (2224G>A), GGG45GGA (2230G>A), AGA72AGG (2311A>G), AAG82AAA (2341G>A), GAC86GAT (2353C>T), TTC87TTT (2356C>T), GAA89GAG (2362A>G), CCA95CCG (2380A>G), CCC97CCA (2386C>A), AAA104AAG (2407A>G), GGT112GGG (2431T>G), CCC119CCT (2452C>T), GAA122AAG (2459G>A 2461A>G), GAC123GAT (2464C>T), TAT127TAC (2476T>C), TTT130TTC (2485T>C), ATA135ACC (2499T>C 2500A>C), GGG141GGA (2518G>A), ATT142GTT (2519A>G), AGA143AGG (2524A>G), TAT144TAC (2527T>C), CAG151CAA (2548G>A), AGT162TAT (2579A>T 2580G>A), GAG169GAT (2602G>T), CCT170CCC (2605T>C), AAA173GCA (2612A>G 2613A>C), CAA174AAA (2615C>A), TAT181TAC (2638T>C), GGA190GGG (2665A>G), GGG196GGA (2683G>A), GAG203GAA (2704G>A), CTG205TTA (2708C>T 2710G>A), CAA207GAA (2714C>G), CTG209CTA (2722G>A), TTG210CTG (2723T>C), AGG211AAA (2727G>A 2728G>A), CTT214TTA (2735C>T 2737T>A), ACC215ACT (2740C>T), CAG222CAA (2761G>A), CCT225CCC (2770T>C), GGT231GGG (2788T>G), GTA241GTG (2818A>G), GTG245CAA (2828G>C 2829T>A 2830G>A), CTG246TTG (2831C>T), GAA248GAC (2839A>C), AAA249AAG (2842A>G), GAC256GAT (2863C>T), GTG261GTA (2878G>A), GGG262GGA (2881G>A), TTG264CTA (2885T>C 2887G>A), TAC271TAT (2908C>T), AGG277AAA (2925G>A 2926G>A), AGA284AGG (2947A>G), ACC286GCC (2951A>G), AAA287AAG (2956A>G), GAA291GAC (2968A>C), GTA292ATA (2969G>A), ATA293GTG (2972A>G 2974A>G), CTA295CTG (2980A>G), ACA296ACT (2983A>T), GAA297ACA (2984G>A 2985A>C), CTA301TTA (2996C>T), CTG303TTG (3002C>T), GAA305GAG (3010A>G), AAC306AAT (3013C>T), AGA307AGG (3016A>G), GGA316GGG (3043A>G), GTG317GCA (3045T>C 3046G>A), CCA321CCG (3058A>G), AAG331AAA (3088G>A), CAG332CAA (3091G>A), GGC335GGG (3100C>G), CTG349CTA (3142G>A), AAA353AAG (3154A>G), AGA356AAA (3162G>A), GGT359TCT (3170G>T 3171G>C), CAA367CAG (3196A>G), GAG370GAA (3205G>A), AAA374AAG (3217A>G), ACC376TCT (3221A>T 3223C>T), ACA377CTA (3224A>C 3225C>T), GGA384GGC (3247A>C), AAA388AAG (3259A>G), AAA390AGA (3264A>G), CTG391CTA (3268G>A), CAA394TTA (3275C>T 3276A>T), AAG395AAA (3280G>A), GAA396GAG (3283A>G), GAA399GAT (3292A>T), TAT405TAC (3310T>C), GTT417GTC (3346T>C), CCT420CCC (3355T>C), CCC421CCT (3358C>T), TTA422CTA (3359T>C), GTG423GTA (3364G>A), TTA425CTA (3368T>C), TAC427TAT (3376C>T), GAG430GAA (3385G>A), AAA431ACA (3387A>C), GAA432GAG (3391A>G)
1288100%197595.9%288 (100%)270 (93.8%)0/0/0/00
Protein mutations:D10E (3805T>G), S17N (3825G>A 3826T>C), L28I (3857C>A 3859G>A), P30A (3863C>G), V72I (3989G>A), I84L (4025A>C), S119T (4131G>C), G123S (4142G>A), R127K (4155G>A), K136Q (4181A>C), V165I (4268G>A), V201I (4376G>A), K211R (4407A>G), T218I (4428C>T), N232D (4469A>G 4471T>C), L234V (4475C>G), D256E (4543C>A), S283G (4622A>G)
Codon mutations:GGA4GGG (3787A>G), GCC8GCA (3799C>A), CAA9CAG (3802A>G), GAT10GAG (3805T>G), GAG13GAA (3814G>A), AGT17AAC (3825G>A 3826T>C), AAC27AAT (3856C>T), CTG28ATA (3857C>A 3859G>A), CCT30GCT (3863C>G), GCC38GCT (3889C>T), GGA47GGG (3916A>G), GAC55GAT (3940C>T), AGT57AGC (3946T>C), GGA59GGG (3952A>G), CTA63TTA (3962C>T), GTT72ATT (3989G>A), GTT77GTC (4006T>C), GCC80GCT (4015C>T), GGA82GGG (4021A>G), TAT83TAC (4024T>C), ATA84CTA (4025A>C), ATT89ATC (4042T>C), GGG94GGA (4057G>A), CAG95CAA (4060G>A), GAA96GAG (4063A>G), GCA98GCC (4069A>C), TAT99TAC (4072T>C), TTT100TTC (4075T>C), CTT101CTA (4078T>A), TTA102CTA (4079T>C), AAA103AAG (4084A>G), ACT115ACA (4120T>A), AGC119ACC (4131G>C), GGT123AGT (4142G>A), GCT124GCC (4147T>C), AGG127AAG (4155G>A), GCC128GCA (4159C>A), GCC129GCT (4162C>T), GCG133GCA (4174G>A), GGA134GGT (4177A>T), AAG136CAG (4181A>C), CCC142CCT (4201C>T), AAT144AAC (4207T>C), ATT161ATC (4258T>C), GTA165ATA (4268G>A), GAT167GAC (4276T>C), CAG168CAA (4279G>A), GTA176GTC (4303A>C), ATC182ATT (4321C>T), GGG193GGA (4354G>A), GTA201ATA (4376G>A), AAA211AGA (4407A>G), ACA218ATA (4428C>T), TTT223TTC (4444T>C), AAT232GAC (4469A>G 4471T>C), CTT234GTT (4475C>G), CTC241CTA (4498C>A), GTA250GTC (4525A>C), GAT253GAC (4534T>C), GAC256GAA (4543C>A), AAA258AAG (4549A>G), GTG260GTT (4555G>T), AGT283GGT (4622A>G)
1501100%302787.4%496 (98.8%)422 (84.1%)1/5/0/02
Protein mutations:E12K (369G>A), R15A (378C>G 379G>C 380A>T), K30R (424A>G), I34L (435A>C), V46L (471G>C), N47D (474A>G), Q59K (510C>A), L61I (516C>A 518G>A), R76K (562G>A), V82I (579G>A), T84V (585A>G 586C>T), C87Y (595G>A), R91K (607G>A), I92V (609A>G), I94V (615A>G), D102E (641C>G), I104L (645A>C), S111G (666A>G), K112R (669A>C 670A>G), K113Q (672A>C), A115T (678G>A), A119T (690G>A 692A>T), D121E (698C>A), T122K (700C>A), H124_Q127del (705_716delCACAGCAATCAG), I138L (747A>C 749C>T), A146S (771G>T 773C>T), I147L (774A>T), V159I (810G>A), E203D (944G>C), V215L (978G>T 980G>A), V218T (987G>A 988T>C 989G>A), H219Q (992T>G), A224P (1005G>C 1007A>C), M228I (1019G>A), G248Q (1077G>C 1078G>A), N252G (1089A>G 1090A>G 1091T>C), I256V (1101A>G), T280V (1173A>G 1174C>T), Y301F (1237A>T), S310T (1263T>A), N315G (1278A>G 1279A>G), E319D (1292A>C), A340G (1354C>G), G357S (1404G>A), V370A (1444T>C), S373T (1452T>A), T375A (1458A>G 1460C>A), R380K (1474G>A), G381S (1476G>A 1478C>T), R384K (1486G>A), N385G (1488A>G 1489A>G), K388R (1498A>G 1499G>A), T401I (1537C>T), R403K (1543G>A), K418R (1588A>G 1589G>A), Y441N (1656T>A), L449I (1680C>A 1682T>C), S451N (1687G>A), T456S (1701A>T), E460A (1714A>C), S462N (1720G>A), R464G (1725A>G), S465F (1729C>T 1730T>C), G466R (1731G>A), V467E (1735T>A 1736A>G), T471del (1746_1748delACT), P473A (1752C>G), Q474P (1756A>C), P478Q (1768C>A), I479K (1771T>A), K481E (1776A>G), E482G (1780A>G), P485_L486insP (1790_1791insCCC), T487A (1794A>G), R490K (1804G>A 1805G>A), S498* (1828C>A)
Codon mutations:GAA12AAA (369G>A), CGA15GCT (378C>G 379G>C 380A>T), CCA23CCG (404A>G), AAA30AGA (424A>G), TTA31CTA (426T>C), ATA34CTA (435A>C), TTC44TTT (467C>T), GTT46CTT (471G>C), AAT47GAT (474A>G), CCT48CCA (479T>A), CTG50CTT (485G>T), TTA51CTA (486T>C), AGA58CGA (507A>C), CAA59AAA (510C>A), CTG61ATA (516C>A 518G>A), CTA64TTA (525C>T), GAA74GAG (557A>G), CTT75CTC (560T>C), AGA76AAA (562G>A), GTA82ATA (579G>A), ACC84GTC (585A>G 586C>T), TGT87TAT (595G>A), GTG88GTA (599G>A), AGG91AAG (607G>A), ATA92GTA (609A>G), ATA94GTA (615A>G), GAA99GAG (632A>G), GAC102GAG (641C>G), ATA104CTA (645A>C), GAG107GAA (656G>A), AGT111GGT (666A>G), AAG112CGG (669A>C 670A>G), AAA113CAA (672A>C), AAA114AAG (677A>G), GCA115ACA (678G>A), GCA118GCG (689A>G), GCA119ACT (690G>A 692A>T), GAC121GAA (698C>A), ACA122AAA (700C>A), GGA123GGG (704A>G), CAC124_CAG127del (705_716delCACAGCAATCAG), AGC129AGT (722C>T), GTG135GTA (740G>A), AAC137AAT (746C>T), ATC138CTT (747A>C 749C>T), GGG140GGA (755G>A), CAT144CAC (767T>C), GCC146TCT (771G>T 773C>T), ATA147TTA (774A>T), AAA157AAG (806A>G), GTA158GTG (809A>G), GTA159ATA (810G>A), TTC164TTT (827C>T), AGC165AGT (830C>T), GTG168GTA (839G>A), GGA178GGG (869A>G), ACC180ACT (875C>T), CTA188TTA (897C>T), AAC189AAT (902C>T), GAG203GAC (944G>C), GAT213GAC (974T>C), GTG215TTA (978G>T 980G>A), GTG218ACA (987G>A 988T>C 989G>A), CAT219CAG (992T>G), GGG221GGA (998G>A), CCT222CCC (1001T>C), ATT223ATC (1004T>C), GCA224CCC (1005G>C 1007A>C), GGC226GGT (1013C>T), ATG228ATA (1019G>A), AGA229AGG (1022A>G), CCA231CCT (1028A>T), GAC235GAT (1040C>T), GCA237GCT (1046A>T), GGA248CAA (1077G>C 1078G>A), AAT252GGC (1089A>G 1090A>G 1091T>C), AAT253AAC (1094T>C), ATC256GTC (1101A>G), GTA258GTG (1109A>G), ATT261ATA (1118T>A), ATA266ATC (1133A>C), CTG268CTA (1139G>A), ACC280GTC (1173A>G 1174C>T), CTG283TTG (1182C>T), GGA288GGG (1199A>G), AAG290AAA (1205G>A), CGG299AGG (1230C>A), TAT301TTT (1237A>T), ACT303ACC (1244T>C), GCC306GCT (1253C>T), TCA310ACA (1263T>A), GAG312GAA (1271G>A), AAA314AAG (1277A>G), AAT315GGT (1278A>G 1279A>G), GAA319GAC (1292A>C), ACT332ACC (1331T>C), GCG340GGG (1354C>G), GTA353GTG (1394A>G), CCC356CCT (1403C>T), GGC357AGC (1404G>A), GAA365GAG (1430A>G), GTA370GCA (1444T>C), TCA373ACA (1452T>A), ACC375GCA (1458A>G 1460C>A), AGA380AAA (1474G>A), GGC381AGT (1476G>A 1478C>T), AAT382AAC (1481T>C), AGG384AAG (1486G>A), AAC385GGC (1488A>G 1489A>G), AAG388AGA (1498A>G 1499G>A), AAG391AAA (1508G>A), TGT392TGC (1511T>C), TTC393TTT (1514C>T), GGG399GGA (1532G>A), ACA401ATA (1537C>T), AGA403AAA (1543G>A), AGG409AGA (1562G>A), AAG418AGA (1588A>G 1589G>A), GAT425GAC (1610T>C), TGT426TGC (1613T>C), GAG428GAA (1619G>A), AAG436AAA (1643G>A), ATC437ATT (1646C>T), TAC441AAC (1656T>A), GGA443GGG (1664A>G), CCA445CCC (1670A>C), GGG446GGA (1673G>A), AAT447AAC (1676T>C), TTT448TTC (1679T>C), CTT449ATC (1680C>A 1682T>C), AGC451AAC (1687G>A), AGA452AGG (1691A>G), ACA456TCA (1701A>T), CCA458CCG (1709A>G), GAA460GCA (1714A>C), AGC462AAC (1720G>A), AGG464GGG (1725A>G), TCT465TTC (1729C>T 1730T>C), GGG466AGG (1731G>A), GTA467GAG (1735T>A 1736A>G), ACA470ACC (1745A>C), ACT471del (1746_1748delACT), CCC472CCA (1751C>A), CCT473GCT (1752C>G), CAG474CCG (1756A>C), CCG478CAG (1768C>A), ATA479AAA (1771T>A), AAG481GAG (1776A>G), GAA482GGA (1780A>G), TAT484TAC (1787T>C), CCT485_TTA486insCCC (1790_1791insCCC), ACT487GCT (1794A>G), AGG490AAA (1804G>A 1805G>A), TCG498TAG (1828C>A)
1132100%69584.2%128 (97.0%)104 (78.8%)0/4/0/00
Protein mutations:E12K (369G>A), R15A (378C>G 379G>C 380A>T), K30R (424A>G), I34L (435A>C), V46L (471G>C), N47D (474A>G), Q59K (510C>A), L61I (516C>A 518G>A), R76K (562G>A), V82I (579G>A), T84V (585A>G 586C>T), C87Y (595G>A), R91K (607G>A), I92V (609A>G), I94V (615A>G), D102E (641C>G), I104L (645A>C), S111G (666A>G), K112R (669A>C 670A>G), K113Q (672A>C), A115T (678G>A), A119T (690G>A 692A>T), D121E (698C>A), T122K (700C>A), H124_Q127del (705_716delCACAGCAATCAG)
Codon mutations:GAA12AAA (369G>A), CGA15GCT (378C>G 379G>C 380A>T), CCA23CCG (404A>G), AAA30AGA (424A>G), TTA31CTA (426T>C), ATA34CTA (435A>C), TTC44TTT (467C>T), GTT46CTT (471G>C), AAT47GAT (474A>G), CCT48CCA (479T>A), CTG50CTT (485G>T), TTA51CTA (486T>C), AGA58CGA (507A>C), CAA59AAA (510C>A), CTG61ATA (516C>A 518G>A), CTA64TTA (525C>T), GAA74GAG (557A>G), CTT75CTC (560T>C), AGA76AAA (562G>A), GTA82ATA (579G>A), ACC84GTC (585A>G 586C>T), TGT87TAT (595G>A), GTG88GTA (599G>A), AGG91AAG (607G>A), ATA92GTA (609A>G), ATA94GTA (615A>G), GAA99GAG (632A>G), GAC102GAG (641C>G), ATA104CTA (645A>C), GAG107GAA (656G>A), AGT111GGT (666A>G), AAG112CGG (669A>C 670A>G), AAA113CAA (672A>C), AAA114AAG (677A>G), GCA115ACA (678G>A), GCA118GCG (689A>G), GCA119ACT (690G>A 692A>T), GAC121GAA (698C>A), ACA122AAA (700C>A), GGA123GGG (704A>G), CAC124_CAG127del (705_716delCACAGCAATCAG), AGC129AGT (722C>T)
1231100%151593.5%231 (100%)211 (91.3%)0/0/0/00
Protein mutations:I6L (747A>C 749C>T), A14S (771G>T 773C>T), I15L (774A>T), V27I (810G>A), E71D (944G>C), V83L (978G>T 980G>A), V86T (987G>A 988T>C 989G>A), H87Q (992T>G), A92P (1005G>C 1007A>C), M96I (1019G>A), G116Q (1077G>C 1078G>A), N120G (1089A>G 1090A>G 1091T>C), I124V (1101A>G), T148V (1173A>G 1174C>T), Y169F (1237A>T), S178T (1263T>A), N183G (1278A>G 1279A>G), E187D (1292A>C), A208G (1354C>G), G225S (1404G>A)
Codon mutations:GTG3GTA (740G>A), AAC5AAT (746C>T), ATC6CTT (747A>C 749C>T), GGG8GGA (755G>A), CAT12CAC (767T>C), GCC14TCT (771G>T 773C>T), ATA15TTA (774A>T), AAA25AAG (806A>G), GTA26GTG (809A>G), GTA27ATA (810G>A), TTC32TTT (827C>T), AGC33AGT (830C>T), GTG36GTA (839G>A), GGA46GGG (869A>G), ACC48ACT (875C>T), CTA56TTA (897C>T), AAC57AAT (902C>T), GAG71GAC (944G>C), GAT81GAC (974T>C), GTG83TTA (978G>T 980G>A), GTG86ACA (987G>A 988T>C 989G>A), CAT87CAG (992T>G), GGG89GGA (998G>A), CCT90CCC (1001T>C), ATT91ATC (1004T>C), GCA92CCC (1005G>C 1007A>C), GGC94GGT (1013C>T), ATG96ATA (1019G>A), AGA97AGG (1022A>G), CCA99CCT (1028A>T), GAC103GAT (1040C>T), GCA105GCT (1046A>T), GGA116CAA (1077G>C 1078G>A), AAT120GGC (1089A>G 1090A>G 1091T>C), AAT121AAC (1094T>C), ATC124GTC (1101A>G), GTA126GTG (1109A>G), ATT129ATA (1118T>A), ATA134ATC (1133A>C), CTG136CTA (1139G>A), ACC148GTC (1173A>G 1174C>T), CTG151TTG (1182C>T), GGA156GGG (1199A>G), AAG158AAA (1205G>A), CGG167AGG (1230C>A), TAT169TTT (1237A>T), ACT171ACC (1244T>C), GCC174GCT (1253C>T), TCA178ACA (1263T>A), GAG180GAA (1271G>A), AAA182AAG (1277A>G), AAT183GGT (1278A>G 1279A>G), GAA187GAC (1292A>C), ACT200ACC (1331T>C), GCG208GGG (1354C>G), GTA221GTG (1394A>G), CCC224CCT (1403C>T), GGC225AGC (1404G>A)
114100%6586.7%14 (100%)11 (78.6%)0/0/0/00
Protein mutations:V7A (1444T>C), S10T (1452T>A), T12A (1458A>G 1460C>A)
Codon mutations:GAA2GAG (1430A>G), GTA7GCA (1444T>C), TCA10ACA (1452T>A), ACC12GCA (1458A>G 1460C>A)
155100%41389.6%55 (100%)47 (85.5%)0/0/0/00
Protein mutations:R3K (1474G>A), G4S (1476G>A 1478C>T), R7K (1486G>A), N8G (1488A>G 1489A>G), K11R (1498A>G 1499G>A), T24I (1537C>T), R26K (1543G>A), K41R (1588A>G 1589G>A)
Codon mutations:AGA3AAA (1474G>A), GGC4AGT (1476G>A 1478C>T), AAT5AAC (1481T>C), AGG7AAG (1486G>A), AAC8GGC (1488A>G 1489A>G), AAG11AGA (1498A>G 1499G>A), AAG14AAA (1508G>A), TGT15TGC (1511T>C), TTC16TTT (1514C>T), GGG22GGA (1532G>A), ACA24ATA (1537C>T), AGA26AAA (1543G>A), AGG32AGA (1562G>A), AAG41AGA (1588A>G 1589G>A), GAT48GAC (1610T>C), TGT49TGC (1613T>C), GAG51GAA (1619G>A)
116100%12090.2%16 (100%)15 (93.8%)0/0/0/00
Protein mutations:Y9N (1656T>A)
Codon mutations:AAG4AAA (1643G>A), ATC5ATT (1646C>T), TAC9AAC (1656T>A), GGA11GGG (1664A>G), CCA13CCC (1670A>C), GGG14GGA (1673G>A), AAT15AAC (1676T>C), TTT16TTC (1679T>C)
152100%21862.8%51 (96.2%)33 (62.3%)1/1/0/01
Protein mutations:L1I (1680C>A 1682T>C), S3N (1687G>A), T8S (1701A>T), E12A (1714A>C), S14N (1720G>A), R16G (1725A>G), S17F (1729C>T 1730T>C), G18R (1731G>A), V19E (1735T>A 1736A>G), T23del (1746_1748delACT), P25A (1752C>G), Q26P (1756A>C), P30Q (1768C>A), I31K (1771T>A), K33E (1776A>G), E34G (1780A>G), P37_L38insP (1790_1791insCCC), T39A (1794A>G), R42K (1804G>A 1805G>A), S50* (1828C>A)
Codon mutations:CTT1ATC (1680C>A 1682T>C), AGC3AAC (1687G>A), AGA4AGG (1691A>G), ACA8TCA (1701A>T), CCA10CCG (1709A>G), GAA12GCA (1714A>C), AGC14AAC (1720G>A), AGG16GGG (1725A>G), TCT17TTC (1729C>T 1730T>C), GGG18AGG (1731G>A), GTA19GAG (1735T>A 1736A>G), ACA22ACC (1745A>C), ACT23del (1746_1748delACT), CCC24CCA (1751C>A), CCT25GCT (1752C>G), CAG26CCG (1756A>C), CCG30CAG (1768C>A), ATA31AAA (1771T>A), AAG33GAG (1776A>G), GAA34GGA (1780A>G), TAT36TAC (1787T>C), CCT37_TTA38insCCC (1790_1791insCCC), ACT39GCT (1794A>G), AGG42AAA (1804G>A 1805G>A), TCG50TAG (1828C>A)
1193100%126686.4%193 (100%)162 (83.9%)0/0/0/01
Protein mutations:R19N (4642G>A 4643A>C), H27Y (4665C>T), Y30H (4674T>C), V31I (4677G>A), G33K (4683G>A 4684G>A), R36K (4693G>A 4694G>A), Y44F (4717A>T), P47R (4725C>A 4726C>G 4727T>G), R50K (4735G>A), G60E (4765G>A), D61T (4767G>A 4768A>C 4769T>A), R63E (4773A>G 4774G>A), H73L (4804A>T), T74P (4806A>C), K91Q (4857A>C 4859A>G), K92G (4860A>G 4861A>G), S95R (4871C>A), V98I (4878G>A), E101G (4888A>G 4889A>C), L109I (4911C>A 4913G>A), D117E (4937C>A), L124I (4956T>A), I128K (4969T>A), V129I (4971G>A), E134N (4986G>A 4988A>C), A151T (5037G>A), T155A (5049A>G 5051A>T), I159T (5062T>C), T167Q (5085A>C 5086C>A), T170V (5094A>G 5095C>T), K181R (5128A>G)
Codon mutations:CAA12CAG (4622A>G), AGA19AAC (4642G>A 4643A>C), CAC27TAC (4665C>T), TAT30CAT (4674T>C), GTT31ATT (4677G>A), GGG33AAG (4683G>A 4684G>A), GCT35GCC (4691T>C), AGG36AAA (4693G>A 4694G>A), TAT44TTT (4717A>T), CCT47AGG (4725C>A 4726C>G 4727T>G), AGA50AAA (4735G>A), GGG60GAG (4765G>A), GAT61ACA (4767G>A 4768A>C 4769T>A), AGA63GAA (4773A>G 4774G>A), TTG64TTA (4778G>A), TAT69TAC (4793T>C), GGT71GGG (4799T>G), CAT73CTT (4804A>T), ACA74CCA (4806A>C), TTG81CTG (4827T>C), AAA91CAG (4857A>C 4859A>G), AAG92GGG (4860A>G 4861A>G), AGA93AGG (4865A>G), AGC95AGA (4871C>A), GTA98ATA (4878G>A), GAA101GGC (4888A>G 4889A>C), CTA102CTG (4892A>G), CTA106CTG (4904A>G), ATT107ATC (4907T>C), CTG109ATA (4911C>A 4913G>A), TAC111TAT (4919C>T), GAC113GAT (4925C>T), GAC117GAA (4937C>A), GCT119GCC (4943T>C), AGA121AGG (4949A>G), AAG122AAA (4952G>A), TTA124ATA (4956T>A), CAC127CAT (4967C>T), ATA128AAA (4969T>A), GTT129ATT (4971G>A), GAA134AAC (4986G>A 4988A>C), GTA142GTG (5012A>G), TAC147TAT (5027C>T), GCA151ACA (5037G>A), ACA155GCT (5049A>G 5051A>T), ATA159ACA (5062T>C), CCA161CCG (5069A>G), GTT166GTC (5084T>C), ACG167CAG (5085A>C 5086C>A), CTG169CTA (5093G>A), ACA170GTA (5094A>G 5095C>T), GAG171GAA (5099G>A), GAT172GAC (5102T>C), AAG181AGG (5128A>G), CAC187CAT (5147C>T)
197100%68693.1%97 (100%)89 (91.8%)0/0/0/01
Protein mutations:H15Y (5147C>T), E21D (5167G>T), I37P (5213A>C 5214T>C 5215T>G), G41S (5225G>A), E48N (5246G>A 5248A>C), A55E (5268C>A), V83I (5352G>A), A89V (5371C>T 5372A>G)
Codon mutations:CAA8CAG (5128A>G), CAC15TAC (5147C>T), GAG21GAT (5167G>T), ATT37CCG (5213A>C 5214T>C 5215T>G), GGC41AGC (5225G>A), GGG43GGA (5233G>A), GAA48AAC (5246G>A 5248A>C), ACT49ACC (5251T>C), GCA55GAA (5268C>A), GTG57GTT (5275G>T), GAA58GAG (5278A>G), GCC59GCA (5281C>A), AGA62AGG (5290A>G), ATT63ATA (5293T>A), CTG64TTG (5294C>T), CTG67CTA (5305G>A), TGT76TGC (5333T>C), CGA77CGT (5336A>T), GTT83ATT (5352G>A), AGG87AGA (5366G>A), GCA89GTG (5371C>T 5372A>G), GCC93GCT (5384C>T), TAG97TAA (5396G>A)
187100%52775.4%87 (100%)62 (71.3%)0/0/0/00
Protein mutations:P3L (5384C>T), R7N (5396G>A 5397A>T), E9D (5403G>T), K12N (5412G>C), K19T (5432A>C), A21P (5437G>C), N24R (5447A>G 5448T>A), K29Q (5461A>C), Q35Y (5479C>T 5481A>C), V36W (5482G>T 5483T>G 5484T>G), I39T (5492T>C), A42G (5501C>G), R56P (5543G>C), A58T (5548G>A), H59P (5552A>C), N61S (5558A>G), T64I (5567C>T 5568T>A), A67D (5576C>A), S68F (5579C>T), L69V (5581C>G), S70P (5584T>C), T74I (7930C>T 7931C>A), P77A (7938C>G), D80N (7947G>A), *87S (7969A>C)
Codon mutations:CCA3CTA (5384C>T), AGA7AAT (5396G>A 5397A>T), CTA8TTA (5398C>T), GAG9GAT (5403G>T), AAG12AAC (5412G>C), AGT16AGC (5424T>C), AAA19ACA (5432A>C), GCT21CCT (5437G>C), AAT24AGA (5447A>G 5448T>A), TGC25TGT (5451C>T), AAG29CAG (5461A>C), TGC34TGT (5478C>T), CAA35TAC (5479C>T 5481A>C), GTT36TGG (5482G>T 5483T>G 5484T>G), TGT37TGC (5487T>C), TTC38TTT (5490C>T), ATA39ACA (5492T>C), ACA40ACG (5496A>G), AAA41AAG (5499A>G), GCC42GGC (5501C>G), CGA56CCA (5543G>C), GCT58ACT (5548G>A), CAT59CCT (5552A>C), CAG60CAA (5556G>A), AAC61AGC (5558A>G), ACT64ATA (5567C>T 5568T>A), GCT67GAT (5576C>A), TCT68TTT (5579C>T), CTA69GTA (5581C>G), TCA70CCA (5584T>C), ACC74ATA (7930C>T 7931C>A), CCC77GCC (7938C>G), GAC80AAC (7947G>A), TAG87TCG (7969A>C)
1117100%61074.9%117 (100%)87 (74.4%)0/0/0/01
Protein mutations:E10Q (5543G>C), I13L (5552A>C), R14K (5556G>A), T15A (5558A>G), L18Y (5567C>T 5568T>A), L21I (5576C>A), P28Y (7930C>T 7931C>A), N30K (7938C>G), E47A (7988A>C 7989G>A), H53R (8006A>G), S54E (8008T>G 8009C>A), I59F (8023A>T 8025C>T), G61S (8029G>A), T62S (8032A>T), Y63C (8036A>G 8037T>C), S67P (8047T>C), T82H (8092A>C 8093C>A), L83I (8095C>A), D84N (8098G>A), N86S (8105A>G), T91Q (8119A>C 8120C>A 8121T>G), S92G (8122T>G 8123C>G 8124T>G), G93A (8126G>C 8127G>T), T94E (8128A>G 8129C>A), Q95E (8131C>G), P100S (8146C>T), L103S (8156T>C 8157G>T), V104G (8159T>G), P107H (8168C>A 8169T>C), E111G (8180A>G)
Codon mutations:GAA10CAA (5543G>C), GAG11GAA (5548G>A), ATC13CTC (5552A>C), AGA14AAA (5556G>A), ACA15GCA (5558A>G), CTC18TAC (5567C>T 5568T>A), CTT21ATT (5576C>A), CTC22TTG (5579C>T 5581C>G), TAT23TAC (5584T>C), CCT28TAT (7930C>T 7931C>A), AAC30AAG (7938C>G), GGG33GGA (7947G>A), AGA41CGA (7969A>C), AGA43AGG (7977A>G), GAG47GCA (7988A>C 7989G>A), AGA48AGG (7992A>G), CAG49CAA (7995G>A), CAT53CGT (8006A>G), TCG54GAG (8008T>G 8009C>A), AGT56AGC (8016T>C), ATC59TTT (8023A>T 8025C>T), GGC61AGC (8029G>A), ACT62TCT (8032A>T), TAT63TGC (8036A>G 8037T>C), TCT67CCT (8047T>C), GAG69GAA (8055G>A), CCA76CCG (8076A>G), CCG77CCA (8079G>A), ACT82CAT (8092A>C 8093C>A), CTT83ATT (8095C>A), GAT84AAT (8098G>A), TGT85TGC (8103T>C), AAC86AGC (8105A>G), ACT91CAG (8119A>C 8120C>A 8121T>G), TCT92GGG (8122T>G 8123C>G 8124T>G), GGG93GCT (8126G>C 8127G>T), ACG94GAG (8128A>G 8129C>A), CAG95GAG (8131C>G), CCT100TCT (8146C>T), TTG103TCT (8156T>C 8157G>T), GTG104GGG (8159T>G), CCT107CAC (8168C>A 8169T>C), GAG111GGG (8180A>G)
183100%31458.1%82 (98.8%)46 (55.4%)0/1/0/01
Protein mutations:Q2S (5611C>T 5612A>C), P3N (5614C>A 5615C>A), I4L (5617A>T 5619A>G), P5L (5620C>T 5621C>T), I6A (5623A>G 5624T>C), V7I (5626G>A), A8G (5630C>G 5631A>C), V10A (5636T>C), V13I (5644G>A), I16L (5653A>C), A19T (5662G>A), S24T (5677T>A 5679C>T), V26A (5684T>C), I27Y (5686A>T 5687T>A 5688C>T), I33L (5704A>C 5706A>G), L34V (5707T>G), D40N (5725G>A 5727C>T), I43Y (5734A>T 5735T>A), D44K (5737G>A 5739T>A), L46I (5743C>A), I47S (5747T>G 5748A>C), E60D (5787A>T), I61A (5788A>G 5789T>C), S62E (5791T>G 5792C>A 5793A>G), A63E (5795C>A), V65A (5801T>C 5802G>A), E66A (5804A>C 5805G>A), M67L (5806A>C 5808G>T), V69del (5813_5815delTGG), M71V (5818A>G), H73P (5825A>C 5826C>T), H74F (5827C>T 5828A>T), A75I (5830G>A 5831C>T), W77G (5836T>G), V79I (5842G>A), D80N (5845G>A), D81N (5848G>A)
Codon mutations:CAA2TCA (5611C>T 5612A>C), CCT3AAT (5614C>A 5615C>A), ATA4TTG (5617A>T 5619A>G), CCA5TTA (5620C>T 5621C>T), ATA6GCA (5623A>G 5624T>C), GTA7ATA (5626G>A), GCA8GGC (5630C>G 5631A>C), GTA10GCA (5636T>C), GTA13ATA (5644G>A), ATA16CTA (5653A>C), GCA19ACA (5662G>A), TCC24ACT (5677T>A 5679C>T), GTA26GCA (5684T>C), ATC27TAT (5686A>T 5687T>A 5688C>T), ATA33CTG (5704A>C 5706A>G), TTA34GTA (5707T>G), AGA35AGG (5712A>G), GAC40AAT (5725G>A 5727C>T), ATT43TAT (5734A>T 5735T>A), GAT44AAA (5737G>A 5739T>A), CTA46ATA (5743C>A), ATA47AGC (5747T>G 5748A>C), GAA58GAG (5781A>G), GGA59GGG (5784A>G), GAA60GAT (5787A>T), ATA61GCA (5788A>G 5789T>C), TCA62GAG (5791T>G 5792C>A 5793A>G), GCA63GAA (5795C>A), CTT64TTG (5797C>T 5799T>G), GTG65GCA (5801T>C 5802G>A), GAG66GCA (5804A>C 5805G>A), ATG67CTT (5806A>C 5808G>T), GTG69del (5813_5815delTGG), GAG70GAA (5813_5815delTGG 5817G>A), ATG71GTG (5818A>G), CAC73CCT (5825A>C 5826C>T), CAT74TTT (5827C>T 5828A>T), GCT75ATT (5830G>A 5831C>T), TGG77GGG (5836T>G), GAT78GAC (5841T>C), GTT79ATT (5842G>A), GAT80AAT (5845G>A), GAT81AAT (5848G>A), TAG83TAA (5856G>A)
1857100%461776.9%843 (97.9%)632 (73.4%)4/14/0/01
Protein mutations:K4R (5781A>G), E5G (5784A>G), K6M (5787A>T 5788A>G), Y7Q (5789T>C 5791T>G), Q8R (5792C>A 5793A>G), H9N (5795C>A 5797C>T), L10W (5799T>G), W11Q (5801T>C 5802G>A), R12H (5804A>C 5805G>A 5806A>C), W13L (5808G>T), W15del (5813_5815delTGG), R16K (5817G>A 5818A>G), T19L (5825A>C 5826C>T 5827C>T), M20L (5828A>T 5830G>A), L21F (5831C>T), M24T (5841T>C 5842G>A), M26I (5848G>A), S29N (5856G>A), T31A (5861A>G), K33N (5869A>C), A60S (5948G>T), D62E (5956T>A), T63K (5958C>A), V65A (5964T>C), V87E (6030T>A), N92R (6045A>G 6046T>G), K97E (6059A>G), D99N (6065G>A), E106T (6086G>A 6087A>C 6088G>A), S128T (6153G>C), K130D (6158A>G 6160G>T), T132S (6165C>G), D133N (6167G>A 6169T>C), L134I (6170T>A 6172G>T), L134_K135insA (6172_6173insGCC), K135I (6174A>T 6175G>C), D137G (6180A>G 6181T>C), T140D (6188A>G 6189C>A), N141T (6192A>C), S142I (6195G>T), S143A (6197A>G 6198G>C 6199T>C), S144I (6201G>T), G145N (6203G>A 6204G>A 6205G>T), R146D (6206A>G 6207G>A 6208A>C), M147T (6210T>C 6211G>T), I148L (6212A>C 6214A>G), M149K (6216T>A), K151D (6221A>G 6223A>T), G152P (6224G>C 6225G>C), E153_I154insA (6229_6230insGCA), K155Q (6233A>C), I161T (6252T>C 6253C>A), S162T (6255G>C), T163A (6257A>G), S164E (6260A>G 6261G>A 6262C>A), G167D (6270G>A), V169Q (6275G>C 6276T>A), Q170L (6279A>T), E172V (6285A>T), Y173Q (6287T>C 6289T>G), F175L (6293T>C), I182V (6314A>G), P183Q (6318C>A), D185N (6323G>A 6325T>C), N186K (6328T>G), D187_T188insD (6331_6332insGAC), T188N (6333C>A), T189R (6336C>G 6337C>A), S190T (6339G>C 6340C>A), K192R (6345A>G 6346G>A), T194I (6351C>T), S195N (6354G>A), N197D (6359A>G 6361C>T), V200T (6368G>A 6369T>C), F210W (6399T>G 6400T>G), E211D (6403G>T), F223Y (6438T>A), N230E (6458A>G 6460T>G), T232N (6465C>A 6466G>T), N234T (6471A>C 6472T>A), P238S (6482C>T), T240K (6489C>A 6490A>G), R252K (6525G>A 6526G>A), E268G (6573A>G), V270I (6578G>A), V275Q (6593G>C 6594T>A 6595C>A), F277I (6599T>A), T278S (6602A>T 6604G>A), Q287H (6631G>C), T290E (6638A>G 6639C>A), E293Q (6647G>C 6649A>G), R308S (6692C>T 6693G>C), I309L (6695A>T 6697C>A), Q310_R311del (6698_6703delCAGAGA), A316V (6717C>T), V318Y (6722G>T 6723T>A), I320T (6729T>C), K322E (6734A>G), I323_G324insI (6739_6740insATA), N325D (6743A>G 6745T>C), M326I (6748G>C), Q328K (6752C>A 6754A>G), I333V (6767A>G), R335G (6773A>G), A336T (6776G>A), K337Q (6779A>C), N339R (6786A>G 6787T>G), K343A (6797A>G 6798A>C), Q344K (6800C>A), I345V (6803A>G), A346K (6806G>A 6807C>A 6808T>G), S347A (6809A>G 6810G>C 6811C>A), R350G (6818A>G 6820A>G), E351S (6821G>T 6822A>C 6823A>T), Q352Y (6824C>T 6826A>T), G354del (6830_6832delGGA), N355P (6833A>C 6834A>C), K357A (6839A>G 6840A>C), I360K (6849T>A 6850C>A), K362N (6856G>C), Q363S (6857C>T 6858A>C), P369L (6876C>T), V372T (6884G>A 6885T>C), T373R (6888C>G), S375N (6894G>A), G379M (6905G>A 6906G>T 6907A>G), S387T (6929T>A), T388D (6932A>G 6933C>A 6934A>T), Q389E (6935C>G), S393D (6947A>G 6948G>A 6949T>C), W395K (6953T>A 6954G>A 6955G>A), S398_N406del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), N407D (6989A>G), E409G (6996A>G), G410F (6998G>T 6999G>T 7000A>C), S411N (7002G>A), D412G (7005A>G), I424V (7040A>G 7042A>G), K429E (7055A>G), K432R (7064A>C 7065A>G), P437N (7079C>A 7080C>A), S440A (7088A>G 7089G>C 7090T>A), Q442T (7094C>A 7095A>C), R444T (7101G>C 7102A>C), S446N (7106T>A 7107C>A 7108A>C), N460L (7148A>C 7149A>T 7150T>G), S461N (7152G>A 7153C>T), N463T (7158A>C), E464del (7160G>A 7162_7164delGTC), S465N (7162_7164delGTC 7165C>T), D474N (7190G>A), R476K (7197G>A 7198G>A), K490E (7238A>G), R504Q (7280A>C 7281G>A), Q507K (7289C>A), K510R (7299A>G), I515L (7313A>C), M535I (7375G>A), N553S (7428A>G), I580V (7508A>G), I595L (7553A>C), A607N (7589G>A 7590C>A), A612S (7604G>T), Q621E (7631C>G), N624G (7640A>G 7641A>G 7642T>G), H625N (7643C>A), T626M (7647C>T), D632E (7666C>A), R633K (7668G>A), I635V (7673A>G), N636S (7677A>G), T639S (7685A>T), S640K (7689G>A 7690C>A), L641E (7691T>G 7692T>A), H643Y (7697C>T), S644R (7700T>A 7701C>G 7702C>G), E648D (7714A>C), E662A (7755A>C), N674D (7790A>G), T676S (7796A>T), N677Q (7799A>C 7801T>A), L684I (7820T>A), V693I (7847G>A), A700T (7868G>A), Q710K (7898C>A), L721I (7931C>A), T723S (7938C>G), G726E (7947G>A), E736G (7977A>G), R740Q (7988A>C 7989G>A), D741G (7992A>G), R742K (7995G>A), I746V (8006A>G 8008T>G), V749A (8016T>C), S752F (8025C>T), I756A (8036A>G 8037T>C), S762N (8055G>A), H769R (8076A>G), R770H (8079G>A), L774F (8092A>C), L775I (8093C>A 8095C>A), V778A (8103T>C), T779A (8105A>G), E783D (8119A>C), L784R (8120C>A 8121T>G 8122T>G), L785G (8123C>G 8124T>G), G786L (8126G>C 8127G>T 8128A>G), W796L (8156T>C 8157G>T), W797G (8159T>G), L800T (8168C>A 8169T>C), S804G (8180A>G), V812I (8204G>A), G825W (8243G>T), V832A (8265T>C 8266A>T), V833L (8267G>T 8269A>G), G835R (8273G>A), C837G (8279T>G), R841L (8292G>T), H842N (8294C>A), I854A (8330A>G 8331T>C)
Codon mutations:AAG4AGG (5781A>G), GAG5GGG (5784A>G), AAA6ATG (5787A>T 5788A>G), TAT7CAG (5789T>C 5791T>G), CAG8AGG (5792C>A 5793A>G), CAC9AAT (5795C>A 5797C>T), TTG10TGG (5799T>G), TGG11CAG (5801T>C 5802G>A), AGA12CAC (5804A>C 5805G>A 5806A>C), TGG13TTG (5808G>T), TGG15del (5813_5815delTGG), AGA16AAG (5817G>A 5818A>G), ACC19CTT (5825A>C 5826C>T 5827C>T), ATG20TTA (5828A>T 5830G>A), CTC21TTC (5831C>T), CTT22CTG (5836T>G), ATG24ACA (5841T>C 5842G>A), TTG25TTA (5845G>A), ATG26ATA (5848G>A), AGT29AAT (5856G>A), ACA31GCA (5861A>G), AAA33AAC (5869A>C), TTG34TTA (5872G>A), GTC36GTT (5878C>T), AAG46AAA (5908G>A), ACC50ACT (5920C>T), TTT53TTC (5929T>C), GCA60TCA (5948G>T), GAT62GAA (5956T>A), ACA63AAA (5958C>A), GTA65GCA (5964T>C), GTT68GTC (5974T>C), GCC70GCT (5980C>T), GCC73GCT (5989C>T), GAC78GAT (6004C>T), AAC80AAT (6010C>T), GTA85GTT (6025A>T), TTG86CTG (6026T>C), GTA87GAA (6030T>A), GTG89GTA (6037G>A), AAT92AGG (6045A>G 6046T>G), AAC94AAT (6052C>T), AAA97GAA (6059A>G), GAC99AAC (6065G>A), CAG103CAA (6079G>A), GAG106ACA (6086G>A 6087A>C 6088G>A), GTA120GTG (6130A>G), AAA121AAG (6133A>G), AGT128ACT (6153G>C), AAG130GAT (6158A>G 6160G>T), TGC131TGT (6163C>T), ACT132AGT (6165C>G), GAT133AAC (6167G>A 6169T>C), TTG134ATT (6170T>A 6172G>T), TTG134_AAG135insGCC (6172_6173insGCC), AAG135ATC (6174A>T 6175G>C), GAT137GGC (6180A>G 6181T>C), ACT138ACC (6184T>C), ACC140GAC (6188A>G 6189C>A), AAT141ACT (6192A>C), AGT142ATT (6195G>T), AGT143GCC (6197A>G 6198G>C 6199T>C), AGC144ATC (6201G>T), GGG145AAT (6203G>A 6204G>A 6205G>T), AGA146GAC (6206A>G 6207G>A 6208A>C), ATG147ACT (6210T>C 6211G>T), ATA148CTG (6212A>C 6214A>G), ATG149AAG (6216T>A), GAG150GAA (6220G>A), AAA151GAT (6221A>G 6223A>T), GGA152CCA (6224G>C 6225G>C), GAG153_ATA154insGCA (6229_6230insGCA), AAA155CAA (6233A>C), TGC157TGT (6241C>T), ATC161ACA (6252T>C 6253C>A), AGC162ACC (6255G>C), ACA163GCA (6257A>G), AGC164GAA (6260A>G 6261G>A 6262C>A), GGT167GAT (6270G>A), GTG169CAG (6275G>C 6276T>A), CAG170CTG (6279A>T), GAA172GTA (6285A>T), TAT173CAG (6287T>C 6289T>G), TTT175CTT (6293T>C), ATA182GTA (6314A>G), CCA183CAA (6318C>A), ATA184ATC (6322A>C), GAT185AAC (6323G>A 6325T>C), AAT186AAG (6328T>G), GAT187_ACT188insGAC (6331_6332insGAC), ACT188AAT (6333C>A), ACC189AGA (6336C>G 6337C>A), AGC190ACA (6339G>C 6340C>A), TAT191TAC (6343T>C), AAG192AGA (6345A>G 6346G>A), TTG193CTA (6347T>C 6349G>A), ACA194ATA (6351C>T), AGT195AAT (6354G>A), AAC197GAT (6359A>G 6361C>T), GTC200ACC (6368G>A 6369T>C), GCC204GCT (6382C>T), TCC209TCT (6397C>T), TTT210TGG (6399T>G 6400T>G), GAG211GAT (6403G>T), GCC219GCT (6427C>T), CCG220CCA (6430G>A), TTT223TAT (6438T>A), AAA227AAG (6451A>G), AAT230GAG (6458A>G 6460T>G), AAG231AAA (6463G>A), ACG232AAT (6465C>A 6466G>T), AAT234ACA (6471A>C 6472T>A), GGA235GGG (6475A>G), GGA237GGG (6481A>G), CCA238TCA (6482C>T), TGT239TGC (6487T>C), ACA240AAG (6489C>A 6490A>G), AGC243AGT (6499C>T), AGG252AAA (6525G>A 6526G>A), GTA254GTG (6532A>G), TCA256TCC (6538A>C), CTG259TTG (6545C>T), CTG260TTG (6548C>T), AGT264AGC (6562T>C), GAA268GGA (6573A>G), GTA270ATA (6578G>A), ATT272ATC (6586T>C), GTC275CAA (6593G>C 6594T>A 6595C>A), TTC277ATC (6599T>A), ACG278TCA (6602A>T 6604G>A), GAC279GAT (6607C>T), GCT281GCA (6613T>A), GTA286GTG (6628A>G), CAG287CAC (6631G>C), CTG288CTT (6634G>T), AAC289AAT (6637C>T), ACA290GAA (6638A>G 6639C>A), GAA293CAG (6647G>C 6649A>G), ATC307ATA (6691C>A), CGT308TCT (6692C>T 6693G>C), ATC309TTA (6695A>T 6697C>A), CAG310_AGA311del (6698_6703delCAGAGA), GGG314GGA (6712G>A), AGA315CGA (6713A>C), GCA316GTA (6717C>T), GTT318TAT (6722G>T 6723T>A), ATA320ACA (6729T>C), AAA322GAA (6734A>G), ATA323_GGA324insATA (6739_6740insATA), AAT325GAC (6743A>G 6745T>C), ATG326ATC (6748G>C), CAA328AAG (6752C>A 6754A>G), ATT333GTT (6767A>G), AGA335GGA (6773A>G), GCA336ACA (6776G>A), AAA337CAA (6779A>C), AAT339AGG (6786A>G 6787T>G), ACT341ACG (6793T>G), AAA343GCA (6797A>G 6798A>C), CAG344AAG (6800C>A), ATA345GTA (6803A>G), GCT346AAG (6806G>A 6807C>A 6808T>G), AGC347GCA (6809A>G 6810G>C 6811C>A), AAA348AAG (6814A>G), AGA350GGG (6818A>G 6820A>G), GAA351TCT (6821G>T 6822A>C 6823A>T), CAA352TAT (6824C>T 6826A>T), TTT353TTC (6829T>C), GGA354del (6830_6832delGGA), AAT355CCT (6833A>C 6834A>C), AAA357GCA (6839A>G 6840A>C), ATC360AAA (6849T>A 6850C>A), AAG362AAC (6856G>C), CAA363TCA (6857C>T 6858A>C), CCA369CTA (6876C>T), GTA372ACA (6884G>A 6885T>C), ACG373AGG (6888C>G), CAC374CAT (6892C>T), AGT375AAT (6894G>A), GGA379ATG (6905G>A 6906G>T 6907A>G), GGG380GGA (6910G>A), TCA387ACA (6929T>A), ACA388GAT (6932A>G 6933C>A 6934A>T), CAA389GAA (6935C>G), AGT393GAC (6947A>G 6948G>A 6949T>C), ACT394ACA (6952T>A), TGG395AAA (6953T>A 6954G>A 6955G>A), TTT396TTC (6958T>C), AGT398_AAT406del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), AAC407GAC (6989A>G), ACT408ACA (6994T>A), GAA409GGA (6996A>G), GGA410TTC (6998G>T 6999G>T 7000A>C), AGT411AAT (7002G>A), GAC412GGC (7005A>G), ACA413ACT (7009A>T), ACC415ACT (7015C>T), TGC418TGT (7024C>T), AGA419CGA (7025A>C), ATA424GTG (7040A>G 7042A>G), AAA429GAA (7055A>G), GTA430GTG (7060A>G), AAA432CGA (7064A>C 7065A>G), CCT437AAT (7079C>A 7080C>A), ATC439ATT (7087C>T), AGT440GCA (7088A>G 7089G>C 7090T>A), CAA442ACA (7094C>A 7095A>C), ATT443ATC (7099T>C), AGA444ACC (7101G>C 7102A>C), TCA446AAC (7106T>A 7107C>A 7108A>C), GGG451GGT (7123G>T), TTA454TTG (7132A>G), AAT460CTG (7148A>C 7149A>T 7150T>G), AGC461AAT (7152G>A 7153C>T), AAC462AAT (7156C>T), AAT463ACT (7158A>C), GAG464del (7160G>A 7162_7164delGTC), TCC465AAT (7162_7164delGTC 7165C>T), GGA471GGG (7183A>G), GAT474AAT (7190G>A), AGG476AAA (7197G>A 7198G>A), AAA490GAA (7238A>G), TTA494CTA (7250T>C), AAG502AAA (7276G>A), AGA504CAA (7280A>C 7281G>A), CAG507AAG (7289C>A), AAA510AGA (7299A>G), ATA515CTA (7313A>C), TTG518CTG (7322T>C), GCA526GCT (7348A>T), GCA532GCG (7366A>G), GCC533GCG (7369C>G), ATG535ATA (7375G>A), GGT547GGA (7411T>A), CAG550CAA (7420G>A), AAC553AGC (7428A>G), TTG555CTG (7433T>C), GAG560GAA (7450G>A), CAA567CAG (7471A>G), ATC573ATT (7489C>T), AAG574AAA (7492G>A), ATC580GTC (7508A>G), CTG593CTA (7549G>A), ATT595CTT (7553A>C), GGT597GGC (7561T>C), ATT603ATC (7579T>C), GCT607AAT (7589G>A 7590C>A), CCT609CCC (7597T>C), AAT611AAC (7603T>C), GCT612TCT (7604G>T), CTG619CTT (7627G>T), GAA620GAG (7630A>G), CAG621GAG (7631C>G), AAT624GGG (7640A>G 7641A>G 7642T>G), CAC625AAC (7643C>A), ACG626ATG (7647C>T), GAC632GAA (7666C>A), AGA633AAA (7668G>A), GAA634GAG (7672A>G), ATT635GTT (7673A>G), AAC636AGC (7677A>G), ACA639TCA (7685A>T), AGC640AAA (7689G>A 7690C>A), TTA641GAA (7691T>G 7692T>A), CAC643TAC (7697C>T), TCC644AGG (7700T>A 7701C>G 7702C>G), GAA648GAC (7714A>C), CAA650CAG (7720A>G), CAA653CAG (7729A>G), TTG661TTA (7753G>A), GAA662GCA (7755A>C), TTA663TTG (7759A>G), GAT664GAC (7762T>C), TTG669CTG (7775T>C), AAC674GAC (7790A>G), ACA676TCA (7796A>T), AAT677CAA (7799A>C 7801T>A), TTA684ATA (7820T>A), GTA693ATA (7847G>A), GGT694GGC (7852T>C), GCT700ACT (7868G>A), GTA701GTG (7873A>G), GTG705GTA (7885G>A), CAG710AAG (7898C>A), TAT712TAC (7906T>C), CCA714CCT (7912A>T), TTA715TTG (7915A>G), TCG716TCA (7918G>A), CAC720CAT (7930C>T), CTC721ATC (7931C>A), ACC723AGC (7938C>G), GGA726GAA (7947G>A), ATA733ATC (7969A>C), GAA736GGA (7977A>G), AGA740CAA (7988A>C 7989G>A), GAC741GGC (7992A>G), AGA742AAA (7995G>A), ATT746GTG (8006A>G 8008T>G), CGA747AGA (8009C>A), GTG749GCG (8016T>C), GGA751GGT (8023A>T), TCC752TTC (8025C>T), TTG753TTA (8029G>A), GCA754GCT (8032A>T), ATC756GCC (8036A>G 8037T>C), GAT759GAC (8047T>C), AGC762AAC (8055G>A), CAC769CGC (8076A>G), CGC770CAC (8079G>A), TTA774TTC (8092A>C), CTC775ATA (8093C>A 8095C>A), TTG776TTA (8098G>A), GTA778GCA (8103T>C), ACG779GCG (8105A>G), GAA783GAC (8119A>C), CTT784AGG (8120C>A 8121T>G 8122T>G), CTG785GGG (8123C>G 8124T>G), GGA786CTG (8126G>C 8127G>T 8128A>G), CGC787AGG (8129C>A 8131C>G), GCC792GCT (8146C>T), TGG796CTG (8156T>C 8157G>T), TGG797GGG (8159T>G), CTA800ACA (8168C>A 8169T>C), AGT804GGT (8180A>G), AGT810AGC (8200T>C), GTT812ATT (8204G>A), CTC815CTT (8215C>T), GCC819GCA (8227C>A), GGG825TGG (8243G>T), AGG828AGA (8254G>A), GTA832GCT (8265T>C 8266A>T), GTA833TTG (8267G>T 8269A>G), GGA835AGA (8273G>A), TGT837GGT (8279T>G), CGC841CTC (8292G>T), CAC842AAC (8294C>A), ATT854GCT (8330A>G 8331T>C), CTA856TTA (8336C>T)
128100%9040.9%27 (96.4%)11 (39.3%)0/1/0/00
Protein mutations:K4R (5781A>G), E5G (5784A>G), K6M (5787A>T 5788A>G), Y7Q (5789T>C 5791T>G), Q8R (5792C>A 5793A>G), H9N (5795C>A 5797C>T), L10W (5799T>G), W11Q (5801T>C 5802G>A), R12H (5804A>C 5805G>A 5806A>C), W13L (5808G>T), W15del (5813_5815delTGG), R16K (5817G>A 5818A>G), T19L (5825A>C 5826C>T 5827C>T), M20L (5828A>T 5830G>A), L21F (5831C>T), M24T (5841T>C 5842G>A), M26I (5848G>A)
Codon mutations:AAG4AGG (5781A>G), GAG5GGG (5784A>G), AAA6ATG (5787A>T 5788A>G), TAT7CAG (5789T>C 5791T>G), CAG8AGG (5792C>A 5793A>G), CAC9AAT (5795C>A 5797C>T), TTG10TGG (5799T>G), TGG11CAG (5801T>C 5802G>A), AGA12CAC (5804A>C 5805G>A 5806A>C), TGG13TTG (5808G>T), TGG15del (5813_5815delTGG), AGA16AAG (5817G>A 5818A>G), ACC19CTT (5825A>C 5826C>T 5827C>T), ATG20TTA (5828A>T 5830G>A), CTC21TTC (5831C>T), CTT22CTG (5836T>G), ATG24ACA (5841T>C 5842G>A), TTG25TTA (5845G>A), ATG26ATA (5848G>A)
1483100%249574.9%470 (96.5%)339 (69.6%)4/13/0/00
Protein mutations:S1N (5856G>A), T3A (5861A>G), K5N (5869A>C), A32S (5948G>T), D34E (5956T>A), T35K (5958C>A), V37A (5964T>C), V59E (6030T>A), N64R (6045A>G 6046T>G), K69E (6059A>G), D71N (6065G>A), E78T (6086G>A 6087A>C 6088G>A), S100T (6153G>C), K102D (6158A>G 6160G>T), T104S (6165C>G), D105N (6167G>A 6169T>C), L106I (6170T>A 6172G>T), L106_K107insA (6172_6173insGCC), K107I (6174A>T 6175G>C), D109G (6180A>G 6181T>C), T112D (6188A>G 6189C>A), N113T (6192A>C), S114I (6195G>T), S115A (6197A>G 6198G>C 6199T>C), S116I (6201G>T), G117N (6203G>A 6204G>A 6205G>T), R118D (6206A>G 6207G>A 6208A>C), M119T (6210T>C 6211G>T), I120L (6212A>C 6214A>G), M121K (6216T>A), K123D (6221A>G 6223A>T), G124P (6224G>C 6225G>C), E125_I126insA (6229_6230insGCA), K127Q (6233A>C), I133T (6252T>C 6253C>A), S134T (6255G>C), T135A (6257A>G), S136E (6260A>G 6261G>A 6262C>A), G139D (6270G>A), V141Q (6275G>C 6276T>A), Q142L (6279A>T), E144V (6285A>T), Y145Q (6287T>C 6289T>G), F147L (6293T>C), I154V (6314A>G), P155Q (6318C>A), D157N (6323G>A 6325T>C), N158K (6328T>G), D159_T160insD (6331_6332insGAC), T160N (6333C>A), T161R (6336C>G 6337C>A), S162T (6339G>C 6340C>A), K164R (6345A>G 6346G>A), T166I (6351C>T), S167N (6354G>A), N169D (6359A>G 6361C>T), V172T (6368G>A 6369T>C), F182W (6399T>G 6400T>G), E183D (6403G>T), F195Y (6438T>A), N202E (6458A>G 6460T>G), T204N (6465C>A 6466G>T), N206T (6471A>C 6472T>A), P210S (6482C>T), T212K (6489C>A 6490A>G), R224K (6525G>A 6526G>A), E240G (6573A>G), V242I (6578G>A), V247Q (6593G>C 6594T>A 6595C>A), F249I (6599T>A), T250S (6602A>T 6604G>A), Q259H (6631G>C), T262E (6638A>G 6639C>A), E265Q (6647G>C 6649A>G), R280S (6692C>T 6693G>C), I281L (6695A>T 6697C>A), Q282_R283del (6698_6703delCAGAGA), A288V (6717C>T), V290Y (6722G>T 6723T>A), I292T (6729T>C), K294E (6734A>G), I295_G296insI (6739_6740insATA), N297D (6743A>G 6745T>C), M298I (6748G>C), Q300K (6752C>A 6754A>G), I305V (6767A>G), R307G (6773A>G), A308T (6776G>A), K309Q (6779A>C), N311R (6786A>G 6787T>G), K315A (6797A>G 6798A>C), Q316K (6800C>A), I317V (6803A>G), A318K (6806G>A 6807C>A 6808T>G), S319A (6809A>G 6810G>C 6811C>A), R322G (6818A>G 6820A>G), E323S (6821G>T 6822A>C 6823A>T), Q324Y (6824C>T 6826A>T), G326del (6830_6832delGGA), N327P (6833A>C 6834A>C), K329A (6839A>G 6840A>C), I332K (6849T>A 6850C>A), K334N (6856G>C), Q335S (6857C>T 6858A>C), P341L (6876C>T), V344T (6884G>A 6885T>C), T345R (6888C>G), S347N (6894G>A), G351M (6905G>A 6906G>T 6907A>G), S359T (6929T>A), T360D (6932A>G 6933C>A 6934A>T), Q361E (6935C>G), S365D (6947A>G 6948G>A 6949T>C), W367K (6953T>A 6954G>A 6955G>A), S370_N378del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), N379D (6989A>G), E381G (6996A>G), G382F (6998G>T 6999G>T 7000A>C), S383N (7002G>A), D384G (7005A>G), I396V (7040A>G 7042A>G), K401E (7055A>G), K404R (7064A>C 7065A>G), P409N (7079C>A 7080C>A), S412A (7088A>G 7089G>C 7090T>A), Q414T (7094C>A 7095A>C), R416T (7101G>C 7102A>C), S418N (7106T>A 7107C>A 7108A>C), N432L (7148A>C 7149A>T 7150T>G), S433N (7152G>A 7153C>T), N435T (7158A>C), E436del (7160G>A 7162_7164delGTC), S437N (7162_7164delGTC 7165C>T), D446N (7190G>A), R448K (7197G>A 7198G>A), K462E (7238A>G), R476Q (7280A>C 7281G>A), Q479K (7289C>A), K482R (7299A>G)
Codon mutations:AGT1AAT (5856G>A), ACA3GCA (5861A>G), AAA5AAC (5869A>C), TTG6TTA (5872G>A), GTC8GTT (5878C>T), AAG18AAA (5908G>A), ACC22ACT (5920C>T), TTT25TTC (5929T>C), GCA32TCA (5948G>T), GAT34GAA (5956T>A), ACA35AAA (5958C>A), GTA37GCA (5964T>C), GTT40GTC (5974T>C), GCC42GCT (5980C>T), GCC45GCT (5989C>T), GAC50GAT (6004C>T), AAC52AAT (6010C>T), GTA57GTT (6025A>T), TTG58CTG (6026T>C), GTA59GAA (6030T>A), GTG61GTA (6037G>A), AAT64AGG (6045A>G 6046T>G), AAC66AAT (6052C>T), AAA69GAA (6059A>G), GAC71AAC (6065G>A), CAG75CAA (6079G>A), GAG78ACA (6086G>A 6087A>C 6088G>A), GTA92GTG (6130A>G), AAA93AAG (6133A>G), AGT100ACT (6153G>C), AAG102GAT (6158A>G 6160G>T), TGC103TGT (6163C>T), ACT104AGT (6165C>G), GAT105AAC (6167G>A 6169T>C), TTG106ATT (6170T>A 6172G>T), TTG106_AAG107insGCC (6172_6173insGCC), AAG107ATC (6174A>T 6175G>C), GAT109GGC (6180A>G 6181T>C), ACT110ACC (6184T>C), ACC112GAC (6188A>G 6189C>A), AAT113ACT (6192A>C), AGT114ATT (6195G>T), AGT115GCC (6197A>G 6198G>C 6199T>C), AGC116ATC (6201G>T), GGG117AAT (6203G>A 6204G>A 6205G>T), AGA118GAC (6206A>G 6207G>A 6208A>C), ATG119ACT (6210T>C 6211G>T), ATA120CTG (6212A>C 6214A>G), ATG121AAG (6216T>A), GAG122GAA (6220G>A), AAA123GAT (6221A>G 6223A>T), GGA124CCA (6224G>C 6225G>C), GAG125_ATA126insGCA (6229_6230insGCA), AAA127CAA (6233A>C), TGC129TGT (6241C>T), ATC133ACA (6252T>C 6253C>A), AGC134ACC (6255G>C), ACA135GCA (6257A>G), AGC136GAA (6260A>G 6261G>A 6262C>A), GGT139GAT (6270G>A), GTG141CAG (6275G>C 6276T>A), CAG142CTG (6279A>T), GAA144GTA (6285A>T), TAT145CAG (6287T>C 6289T>G), TTT147CTT (6293T>C), ATA154GTA (6314A>G), CCA155CAA (6318C>A), ATA156ATC (6322A>C), GAT157AAC (6323G>A 6325T>C), AAT158AAG (6328T>G), GAT159_ACT160insGAC (6331_6332insGAC), ACT160AAT (6333C>A), ACC161AGA (6336C>G 6337C>A), AGC162ACA (6339G>C 6340C>A), TAT163TAC (6343T>C), AAG164AGA (6345A>G 6346G>A), TTG165CTA (6347T>C 6349G>A), ACA166ATA (6351C>T), AGT167AAT (6354G>A), AAC169GAT (6359A>G 6361C>T), GTC172ACC (6368G>A 6369T>C), GCC176GCT (6382C>T), TCC181TCT (6397C>T), TTT182TGG (6399T>G 6400T>G), GAG183GAT (6403G>T), GCC191GCT (6427C>T), CCG192CCA (6430G>A), TTT195TAT (6438T>A), AAA199AAG (6451A>G), AAT202GAG (6458A>G 6460T>G), AAG203AAA (6463G>A), ACG204AAT (6465C>A 6466G>T), AAT206ACA (6471A>C 6472T>A), GGA207GGG (6475A>G), GGA209GGG (6481A>G), CCA210TCA (6482C>T), TGT211TGC (6487T>C), ACA212AAG (6489C>A 6490A>G), AGC215AGT (6499C>T), AGG224AAA (6525G>A 6526G>A), GTA226GTG (6532A>G), TCA228TCC (6538A>C), CTG231TTG (6545C>T), CTG232TTG (6548C>T), AGT236AGC (6562T>C), GAA240GGA (6573A>G), GTA242ATA (6578G>A), ATT244ATC (6586T>C), GTC247CAA (6593G>C 6594T>A 6595C>A), TTC249ATC (6599T>A), ACG250TCA (6602A>T 6604G>A), GAC251GAT (6607C>T), GCT253GCA (6613T>A), GTA258GTG (6628A>G), CAG259CAC (6631G>C), CTG260CTT (6634G>T), AAC261AAT (6637C>T), ACA262GAA (6638A>G 6639C>A), GAA265CAG (6647G>C 6649A>G), ATC279ATA (6691C>A), CGT280TCT (6692C>T 6693G>C), ATC281TTA (6695A>T 6697C>A), CAG282_AGA283del (6698_6703delCAGAGA), GGG286GGA (6712G>A), AGA287CGA (6713A>C), GCA288GTA (6717C>T), GTT290TAT (6722G>T 6723T>A), ATA292ACA (6729T>C), AAA294GAA (6734A>G), ATA295_GGA296insATA (6739_6740insATA), AAT297GAC (6743A>G 6745T>C), ATG298ATC (6748G>C), CAA300AAG (6752C>A 6754A>G), ATT305GTT (6767A>G), AGA307GGA (6773A>G), GCA308ACA (6776G>A), AAA309CAA (6779A>C), AAT311AGG (6786A>G 6787T>G), ACT313ACG (6793T>G), AAA315GCA (6797A>G 6798A>C), CAG316AAG (6800C>A), ATA317GTA (6803A>G), GCT318AAG (6806G>A 6807C>A 6808T>G), AGC319GCA (6809A>G 6810G>C 6811C>A), AAA320AAG (6814A>G), AGA322GGG (6818A>G 6820A>G), GAA323TCT (6821G>T 6822A>C 6823A>T), CAA324TAT (6824C>T 6826A>T), TTT325TTC (6829T>C), GGA326del (6830_6832delGGA), AAT327CCT (6833A>C 6834A>C), AAA329GCA (6839A>G 6840A>C), ATC332AAA (6849T>A 6850C>A), AAG334AAC (6856G>C), CAA335TCA (6857C>T 6858A>C), CCA341CTA (6876C>T), GTA344ACA (6884G>A 6885T>C), ACG345AGG (6888C>G), CAC346CAT (6892C>T), AGT347AAT (6894G>A), GGA351ATG (6905G>A 6906G>T 6907A>G), GGG352GGA (6910G>A), TCA359ACA (6929T>A), ACA360GAT (6932A>G 6933C>A 6934A>T), CAA361GAA (6935C>G), AGT365GAC (6947A>G 6948G>A 6949T>C), ACT366ACA (6952T>A), TGG367AAA (6953T>A 6954G>A 6955G>A), TTT368TTC (6958T>C), AGT370_AAT378del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), AAC379GAC (6989A>G), ACT380ACA (6994T>A), GAA381GGA (6996A>G), GGA382TTC (6998G>T 6999G>T 7000A>C), AGT383AAT (7002G>A), GAC384GGC (7005A>G), ACA385ACT (7009A>T), ACC387ACT (7015C>T), TGC390TGT (7024C>T), AGA391CGA (7025A>C), ATA396GTG (7040A>G 7042A>G), AAA401GAA (7055A>G), GTA402GTG (7060A>G), AAA404CGA (7064A>C 7065A>G), CCT409AAT (7079C>A 7080C>A), ATC411ATT (7087C>T), AGT412GCA (7088A>G 7089G>C 7090T>A), CAA414ACA (7094C>A 7095A>C), ATT415ATC (7099T>C), AGA416ACC (7101G>C 7102A>C), TCA418AAC (7106T>A 7107C>A 7108A>C), GGG423GGT (7123G>T), TTA426TTG (7132A>G), AAT432CTG (7148A>C 7149A>T 7150T>G), AGC433AAT (7152G>A 7153C>T), AAC434AAT (7156C>T), AAT435ACT (7158A>C), GAG436del (7160G>A 7162_7164delGTC), TCC437AAT (7162_7164delGTC 7165C>T), GGA443GGG (7183A>G), GAT446AAT (7190G>A), AGG448AAA (7197G>A 7198G>A), AAA462GAA (7238A>G), TTA466CTA (7250T>C), AAG474AAA (7276G>A), AGA476CAA (7280A>C 7281G>A), CAG479AAG (7289C>A), AAA482AGA (7299A>G)
1345100%203182.9%345 (100%)281 (81.4%)0/0/0/00
Protein mutations:I4L (7313A>C), M24I (7375G>A), N42S (7428A>G), I69V (7508A>G), I84L (7553A>C), A96N (7589G>A 7590C>A), A101S (7604G>T), Q110E (7631C>G), N113G (7640A>G 7641A>G 7642T>G), H114N (7643C>A), T115M (7647C>T), D121E (7666C>A), R122K (7668G>A), I124V (7673A>G), N125S (7677A>G), T128S (7685A>T), S129K (7689G>A 7690C>A), L130E (7691T>G 7692T>A), H132Y (7697C>T), S133R (7700T>A 7701C>G 7702C>G), E137D (7714A>C), E151A (7755A>C), N163D (7790A>G), T165S (7796A>T), N166Q (7799A>C 7801T>A), L173I (7820T>A), V182I (7847G>A), A189T (7868G>A), Q199K (7898C>A), L210I (7931C>A), T212S (7938C>G), G215E (7947G>A), E225G (7977A>G), R229Q (7988A>C 7989G>A), D230G (7992A>G), R231K (7995G>A), I235V (8006A>G 8008T>G), V238A (8016T>C), S241F (8025C>T), I245A (8036A>G 8037T>C), S251N (8055G>A), H258R (8076A>G), R259H (8079G>A), L263F (8092A>C), L264I (8093C>A 8095C>A), V267A (8103T>C), T268A (8105A>G), E272D (8119A>C), L273R (8120C>A 8121T>G 8122T>G), L274G (8123C>G 8124T>G), G275L (8126G>C 8127G>T 8128A>G), W285L (8156T>C 8157G>T), W286G (8159T>G), L289T (8168C>A 8169T>C), S293G (8180A>G), V301I (8204G>A), G314W (8243G>T), V321A (8265T>C 8266A>T), V322L (8267G>T 8269A>G), G324R (8273G>A), C326G (8279T>G), R330L (8292G>T), H331N (8294C>A), I343A (8330A>G 8331T>C)
Codon mutations:ATA4CTA (7313A>C), TTG7CTG (7322T>C), GCA15GCT (7348A>T), GCA21GCG (7366A>G), GCC22GCG (7369C>G), ATG24ATA (7375G>A), GGT36GGA (7411T>A), CAG39CAA (7420G>A), AAC42AGC (7428A>G), TTG44CTG (7433T>C), GAG49GAA (7450G>A), CAA56CAG (7471A>G), ATC62ATT (7489C>T), AAG63AAA (7492G>A), ATC69GTC (7508A>G), CTG82CTA (7549G>A), ATT84CTT (7553A>C), GGT86GGC (7561T>C), ATT92ATC (7579T>C), GCT96AAT (7589G>A 7590C>A), CCT98CCC (7597T>C), AAT100AAC (7603T>C), GCT101TCT (7604G>T), CTG108CTT (7627G>T), GAA109GAG (7630A>G), CAG110GAG (7631C>G), AAT113GGG (7640A>G 7641A>G 7642T>G), CAC114AAC (7643C>A), ACG115ATG (7647C>T), GAC121GAA (7666C>A), AGA122AAA (7668G>A), GAA123GAG (7672A>G), ATT124GTT (7673A>G), AAC125AGC (7677A>G), ACA128TCA (7685A>T), AGC129AAA (7689G>A 7690C>A), TTA130GAA (7691T>G 7692T>A), CAC132TAC (7697C>T), TCC133AGG (7700T>A 7701C>G 7702C>G), GAA137GAC (7714A>C), CAA139CAG (7720A>G), CAA142CAG (7729A>G), TTG150TTA (7753G>A), GAA151GCA (7755A>C), TTA152TTG (7759A>G), GAT153GAC (7762T>C), TTG158CTG (7775T>C), AAC163GAC (7790A>G), ACA165TCA (7796A>T), AAT166CAA (7799A>C 7801T>A), TTA173ATA (7820T>A), GTA182ATA (7847G>A), GGT183GGC (7852T>C), GCT189ACT (7868G>A), GTA190GTG (7873A>G), GTG194GTA (7885G>A), CAG199AAG (7898C>A), TAT201TAC (7906T>C), CCA203CCT (7912A>T), TTA204TTG (7915A>G), TCG205TCA (7918G>A), CAC209CAT (7930C>T), CTC210ATC (7931C>A), ACC212AGC (7938C>G), GGA215GAA (7947G>A), ATA222ATC (7969A>C), GAA225GGA (7977A>G), AGA229CAA (7988A>C 7989G>A), GAC230GGC (7992A>G), AGA231AAA (7995G>A), ATT235GTG (8006A>G 8008T>G), CGA236AGA (8009C>A), GTG238GCG (8016T>C), GGA240GGT (8023A>T), TCC241TTC (8025C>T), TTG242TTA (8029G>A), GCA243GCT (8032A>T), ATC245GCC (8036A>G 8037T>C), GAT248GAC (8047T>C), AGC251AAC (8055G>A), CAC258CGC (8076A>G), CGC259CAC (8079G>A), TTA263TTC (8092A>C), CTC264ATA (8093C>A 8095C>A), TTG265TTA (8098G>A), GTA267GCA (8103T>C), ACG268GCG (8105A>G), GAA272GAC (8119A>C), CTT273AGG (8120C>A 8121T>G 8122T>G), CTG274GGG (8123C>G 8124T>G), GGA275CTG (8126G>C 8127G>T 8128A>G), CGC276AGG (8129C>A 8131C>G), GCC281GCT (8146C>T), TGG285CTG (8156T>C 8157G>T), TGG286GGG (8159T>G), CTA289ACA (8168C>A 8169T>C), AGT293GGT (8180A>G), AGT299AGC (8200T>C), GTT301ATT (8204G>A), CTC304CTT (8215C>T), GCC308GCA (8227C>A), GGG314TGG (8243G>T), AGG317AGA (8254G>A), GTA321GCT (8265T>C 8266A>T), GTA322TTG (8267G>T 8269A>G), GGA324AGA (8273G>A), TGT326GGT (8279T>G), CGC330CTC (8292G>T), CAC331AAC (8294C>A), ATT343GCT (8330A>G 8331T>C), CTA345TTA (8336C>T)
1190100%97577.3%180 (94.7%)143 (75.3%)0/10/0/01
Protein mutations:K19R (7433T>C), F21L (7428A>G), E40D (7369C>G), K56R (7322T>C), I59S (7313A>C), F64L (7299A>G), C67F (7289C>A), L70C (7280A>C 7281G>A), N80S (7250T>C), F84S (7238A>G), L98F (7197G>A), S100F (7190G>A), D109del (7162_7164delGTC), S110L (7160G>A), L111V (7156C>T 7158A>C), L113F (7150T>G 7152G>A), L114R (7148A>C 7149A>T), S122R (7123G>T), D127E (7108A>C), E128L (7106T>A 7107C>A), H129Q (7102A>C), L130V (7099T>C 7101G>C), C132V (7094C>A 7095A>C), L134A (7087C>T 7088A>G 7089G>C), G137L (7079C>A 7080C>A), F142R (7064A>C 7065A>G), F145S (7055A>G), I150T (7040A>G), L155R (7024C>T 7025A>C), S162P (7005A>G), P164N (6998G>T 6999G>T), S165P (6994T>A 6996A>G), L167S (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT 6989A>G), F168_L176del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), Q179F (6952T>A 6953T>A 6954G>A), L181S (6947A>G 6948G>A), C185S (6934A>T 6935C>G), V186S (6932A>G 6933C>A), E187V (6929T>A)
Codon mutations:AGT6AGC (7471A>G), GCC13GCT (7450G>A), AAA19AGA (7433T>C), TTC21CTC (7428A>G), TGC23TGT (7420G>A), ATA26ATT (7411T>A), GTC38GTT (7375G>A), GAG40GAC (7369C>G), GCT41GCC (7366A>G), CCT47CCA (7348A>T), AAA56AGA (7322T>C), ATT59AGT (7313A>C), TTT64CTT (7299A>G), TGC67TTC (7289C>A), CTT70TGT (7280A>C 7281G>A), CTC71CTT (7276G>A), AAT80AGT (7250T>C), TTT84TCT (7238A>G), TCC97TCT (7198G>A), CTC98TTC (7197G>A), TCT100TTT (7190G>A), CCT102CCC (7183A>G), TCG108TCA (7165C>T), GAC109del (7162_7164delGTC), TCA110TTA (7160G>A), TTG111GTA (7156C>T 7158A>C), TTG112TTA (7153C>T), CTA113TTC (7150T>G 7152G>A), TTA114AGA (7148A>C 7149A>T), GTT119GTC (7132A>G), AGC122AGA (7123G>T), GAT127GAG (7108A>C), GAA128TTA (7106T>A 7107C>A), CAT129CAG (7102A>C), CTA130GTG (7099T>C 7101G>C), TGT132GTT (7094C>A 7095A>C), CCA133CCT (7090T>A), CTG134GCA (7087C>T 7088A>G 7089G>C), GGG137TTG (7079C>A 7080C>A), TTT142CGT (7064A>C 7065A>G), CCT143CCC (7060A>G), TTC145TCC (7055A>G), TTT149TTC (7042A>G), ATA150ACA (7040A>G), CTG155CGA (7024C>T 7025A>C), AGG158AGA (7015C>T), ATT160ATA (7009A>T), TCA162CCA (7005A>G), CTT163TTG (7000A>C 7002G>A), CCT164AAT (6998G>T 6999G>T), TCA165CCT (6994T>A 6996A>G), TTA167TCA (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT 6989A>G), TTT168_CTA176del (6962_6988delAGTACTTGGAGTACTGAAGGGTCAAAT), TTA177TTG (6958T>C), AAC178AAT (6955G>A), CAA179TTT (6952T>A 6953T>A 6954G>A), GTA180GTG (6949T>C), CTA181TCA (6947A>G 6948G>A), TGT185TCA (6934A>T 6935C>G), GTT186TCT (6932A>G 6933C>A), GAA187GTA (6929T>A)
119091.8%110279.9%190 (100%)142 (74.7%)0/0/0/00
Protein mutations:V10I (8370G>A 8372G>A), I11V (8373A>G), T15A (8385A>G), V16I (8388G>A), M20L (8400A>C), A23T (8409G>A 8411T>C), E24P (8412G>C 8413A>C 8414G>T), D28E (8426T>G), R29G (8427A>G), A33V (8440C>T 8441A>G), R35Q (8446G>A), K39R (8458A>G), H40R (8461A>G 8462T>G), A49R (8487G>A 8488C>G), T51N (8494C>A 8495C>T), A53P (8499G>C), A54D (8503C>A 8504T>C), C55L (8506G>T 8507T>G), E64D (8534G>C), T71R (8554C>G), A83G (8590C>G), H102Y (8646C>T), Q104K (8652C>A 8654A>G), R105K (8656G>A), D108E (8666T>G), I114V (8682A>G), *124W (8713A>G), V133I (8739G>A), F139M (8757T>A 8759T>G), Y143F (8770A>T), E149D (8789G>C), D151E (8795T>G), K152E (8796A>G), I153V (8799A>G), E155K (8805G>A), K158E (8814A>G), T162N (8827C>A), S163C (8829A>T), V168M (8844G>A), L170Q (8851T>A 8852G>A), D174E (8864T>G), P176E (8868C>G 8869C>A 8870G>A), E177D (8873G>C), R178K (8875G>A), E182K (8886G>A), R184E (8892A>G 8893G>A), S187G (8901A>G)
Codon mutations:GTG10ATA (8370G>A 8372G>A), ATT11GTT (8373A>G), ACT15GCT (8385A>G), GTA16ATA (8388G>A), ATG20CTG (8400A>C), GCT23ACC (8409G>A 8411T>C), GAG24CCT (8412G>C 8413A>C 8414G>T), GAT28GAG (8426T>G), AGG29GGG (8427A>G), GCA33GTG (8440C>T 8441A>G), CGA35CAA (8446G>A), CTG37TTA (8451C>T 8453G>A), AAA39AGA (8458A>G), CAT40CGG (8461A>G 8462T>G), GGA41GGG (8465A>G), ATC43ATT (8471C>T), AGT45AGC (8477T>C), ACA48ACT (8486A>T), GCA49AGA (8487G>A 8488C>G), ACC51AAT (8494C>A 8495C>T), GCT53CCT (8499G>C), GCT54GAC (8503C>A 8504T>C), TGT55TTG (8506G>T 8507T>G), CTA58CTG (8516A>G), GAG63GAA (8531G>A), GAG64GAC (8534G>C), GAG65GAA (8537G>A), GTG66GTA (8540G>A), GGT67GGC (8543T>C), ACA71AGA (8554C>G), ACT80ACC (8582T>C), TAC81TAT (8585C>T), GCA83GGA (8590C>G), CTT87CTC (8603T>C), AGC88AGT (8606C>T), CTA100TTA (8640C>T), CAC102TAC (8646C>T), CAA104AAG (8652C>A 8654A>G), AGA105AAA (8656G>A), GAT108GAG (8666T>G), ATC114GTC (8682A>G), TAG124TGG (8713A>G), GTC133ATC (8739G>A), TTT139ATG (8757T>A 8759T>G), GGA140GGG (8762A>G), TAC143TTC (8770A>T), GAG149GAC (8789G>C), GAT151GAG (8795T>G), AAG152GAG (8796A>G), ATA153GTA (8799A>G), GAG155AAG (8805G>A), AAA158GAA (8814A>G), ACC162AAC (8827C>A), AGC163TGC (8829A>T), TTA165CTA (8835T>C), GTG168ATG (8844G>A), CTG170CAA (8851T>A 8852G>A), GGG172GGA (8858G>A), GAT174GAG (8864T>G), GAC175GAT (8867C>T), CCG176GAA (8868C>G 8869C>A 8870G>A), GAG177GAC (8873G>C), AGA178AAA (8875G>A), TTA181CTG (8883T>C 8885A>G), GAG182AAG (8886G>A), AGG184GAG (8892A>G 8893G>A), AGC187GGC (8901A>G), CTA189TTG (8907C>T 8909A>G)
*: Inserts / Deletes / Misaligned / Frameshifts

Analysis details

This analysis was performed with panviral2.43