How it works
From raw sequencing data
to actionable insight, in minutes
Genome Detective is designed for clarity, speed, and trust. It transforms complex NGS data into clear, interpretable results through a fully automated, cloud-based workflow. From raw reads to validated reports, every step is optimized for speed, accuracy, and transparency — without requiring bioinformatics expertise.
Whether you operate a clinical lab, research group, or public health organization, Genome Detective guides you seamlessly from data upload to decision-ready output.
A platform that grows with your workflow
Step 1: Upload your sequencing data
Simple input, flexible formats
Start by uploading your raw sequencing files (FASTQ or FASTA) directly through the secure web interface or via the API. Genome Detective supports data from all major NGS sequencers and accommodates single samples as well as large batch uploads.
- Upload FASTQ files in seconds
- Supports Illumina, Oxford Nanopore, Thermo Fisher and other common platforms
- Secure, encrypted data transfer
- Batch uploads and API access for automated pipelines
Outcome: Your data is safely ingested and prepared for analysis. No preprocessing required.
Clean data, reliable results
Once uploaded, Genome Detective automatically performs quality control and preprocessing to ensure reliable downstream analysis. Low-quality reads are filtered, adapters and primers removed, and datasets optimized, all without manual intervention.
- Automated quality checks and quality reports
- Read trimming and filtering
- Platform-specific optimization
- Transparent QC metrics available for review
Outcome: High-quality input data, ready for confident pathogen detection and characterization
From unknown reads to identified species
Genome Detective’s core algorithms rapidly detect, classify, and subtype viruses, bacteria, fungi and parasites. Using advanced homology-based methods and proprietary technologies such as AGA (Advanced Genome Aligner), the platform identifies both known and novel pathogens with high sensitivity and specificity.
- Broad-spectrum pathogen detection
- Automated virus typing and lineage assignment for some species
- Identification of recombinant and divergent genomes
- Robust performance on mixed or low-abundance samples, even when diverged from the reference database
Outcome: Accurate identification and classification of pathogens — even when standard tools fall short.
Deep insight beyond identification
For detected pathogens, Genome Detective reconstructs genomes and performs detailed variant and mutation analysis. This enables strain differentiation, evolutionary insight, and functional interpretation.
- Full or partial genome assembly
- Variant calling and minority mutation reporting
- Functional annotation of genomic regions
- Comparative analysis across samples
- Automated virus typing and lineage assignment
- Identification of recombinant and divergent genomes
Outcome: Actionable genomic insight to support clinical applications, research, or surveillance.
Results you can trust, and explain
All findings are translated into clear, structured reports with intuitive visualizations. Results are designed to be interpretable by laboratory professionals, clinicians, and researchers alike.
- Clear summaries and detailed result layers
- Interactive visualizations and tables
- Exportable reports (PDF, CSV, JSON)
- Audit-friendly output for regulated environments
Outcome: Decision-ready results that are easy to review, share, and validate.
Fit seamlessly into your workflow
Genome Detective is built to integrate into existing laboratory, research, and surveillance ecosystems. Results can be shared securely, exported to public databases, or fed into downstream analysis pipelines.
- API access for LIMS and bioinformatics workflows
- Secure data sharing with collaborators
- Support for public databases (e.g. GISAID, NCBI, ENA)
- Scalable from single samples to large surveillance programs
Outcome: A platform that grows with your workflow, from individual analyses to global programs.
Why users trust Genome Detective
Data security and privacy are built into the platform. Genome Detective is designed to meet the expectations of regulated environments without compromising usability.
interpretable results
and compliance
and public health settings